516 research outputs found

    The Waterfall of Tiers: A Relocation Cost-Based Theory of Municipal Insolvency and a Proposal for a New Municipal Bankruptcy Regime

    Get PDF
    The \u27non-liquidation assumption\u27 presumes that municipal bankruptcy law exists to provide municipalities a \u27breathing spell\u27 from creditors and disallows the liquidation of municipalities. This assumption rests on the notion that chapter 9 exists solely to help municipalities continue to provide essential public services. This approach runs counter to the prevailing theory of corporate bankruptcy\u27that bankruptcy exists to resolve collection action problems among creditors and maximize social welfare. This Article rejects the \u27non-liquidation assumption\u27 and applies a modified theory of municipal bankruptcy based on corporate bankruptcy theory. This Article further proposes a waterfall bidding alternative municipal bankruptcy regime that looks to promote an efficient market-based allocation of resources

    Data-rich reporting and standards setting following rules-based marking

    Get PDF
    There has been a lot of movement in recent years towards computer-based assessment, or e-assessment. This has tended towards the conversion of paper test models for use on-screen, mimicking existing test construction and question writing processes and data collection models

    Communicating across the pond: Evaluating perceptions of dialectal divergence among American student sojourners in England

    Get PDF
    Although at first glance the differences between British English and American English seem trivial, “apartment” vs. “flat” or “color” vs. “colour, these dialectal divergences immediately create an othering effect. Subtle changes are representative of the deeper implications of this issue; altered language impacts perceptions about the validity and correctness of a written work. My research seeks to understand how the differences between British English and American English impact American student sojourners during an abroad experience in England. Examining how American sojourners perceive dialectal differences and adapt their written rhetoric to match that of a British audience offers valuable insight into the audience awareness of American students. Using a phenomenological research approach, I conducted 13 semi-structured interviews to study audience awareness. Through concept coding, three main themes emerged: sociolinguistic prestige, language globalization and media influence, and visual language variation. Each theme speaks to how American sojourners perceive and approach written language differences during an abroad experience. In a time when language is increasingly divisive and difference is regarded with suspicion, it is critical to consider how language alters perceptions. My research approaches difference with a mindset that respects dialectal divergences and works to form global connections

    The Effects of Cultural Competency Training on Providers Knowledge, Skills and Attitudes Towards the Latino Population

    Get PDF
    Background: Providers in the United States (U.S.) healthcare system need to understand the cultural values, beliefs, and traditions of the growing Latino population. As a result, academic institutions are incorporating cultural competency training in their curricula. However, a noticeable knowledge gap exists for those currently practicing in the healthcare arena, impacting patient and provider satisfaction and healthcare outcomes. Purpose: The purpose of the study was to obtain a baseline assessment of the cultural competence of a select group of Advanced Practice Providers (APPs) caring for the Latino population at the University of Kentucky and provide a targeted educational intervention, followed by a post-intervention assessment utilizing the same evidence-based tool. Conceptual Framework: Schim and Miller’s Cultural Competence Model (CCM) was utilized as the framework for this study. Methodology: This study used a one-group pre-test post-test design to examine the effect of a cultural competency educational module for APPs on their knowledge related to cultural diversity, awareness, and sensitivity. Results: Thirteen participants completed the pre-survey and 11 completed the post-survey. Seven participants completed both the pre and post-surveys. There was no change in the pre and post self-reported overall cultural competency assessment scores in relation to the educational intervention, which was expected with a small sample size. However, it is important to note that the cultural competence behavior (CCB) scores were higher after the educational intervention. Conclusion: The implementation of cultural competency training for Advanced Practice Providers did result in increased CCB scores. However, this study needs to be replicated with a larger, more inclusive sample size

    Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney.

    Get PDF
    Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects. In addition to its role in the CNS, an increasing number of publications have suggested that GABA might also play a role in the regulation of renal function. All three enzymes associated with GABA metabolism; glutamic acid decarboxylase, GABA ?-oxoglutarate transaminase (GABA-T) and succinic semialdehyde dehydrogenase (SSADH) have been localised to the kidney providing the necessary machinery for localised GABA synthesis and metabolism. Moreover GABA receptors have been localised to both tubular and vascular structures in the kidney, and GABA is excreted in urine (~3 ?M) in humans. Despite the collective evidence describing the presence of a GABA system in the kidney, the precise function of such a system requires further clarification. Here we provide an overview of the current renal GABA literature and provide novel data that indicates GABA can act at contractile pericyte cells located along vasa recta capillaries in the renal medulla to potentially regulate medullary blood flow

    Emerging key roles for P2X receptors in the kidney

    Get PDF
    P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature describing a regulatory role of P2 receptors (P2R) in the kidney, there are significantly less data on the regulatory role of P2X receptors (P2XR) compared with that described for metabotropic P2Y. Much of the historical literature describing a role for P2XR in the kidney has focused heavily on the role of P2X1R in the autoregulation of renal blood flow. More recently, however, there has been a plethora of manuscripts providing compelling evidence for additional roles for P2XR in both kidney health and disease. This review summarizes the current evidence for the involvement of P2XR in the regulation of renal tubular and vascular function, and highlights the novel data describing their putative roles in regulating physiological and pathophysiological processes in the kidney

    Sympathetic nerve-derived ATP regulates renal medullary vasa recta diameter via pericyte cells: a role for regulating medullary blood flow?

    Get PDF
    Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa recta via renal pericytes, acting at a variety of membrane bound P2 receptors on descending vasa recta (DVR), and therefore may be able to regulate medullary blood flow (MBF). Regulation of MBF is essential for appropriate urine concentration and providing essential oxygen and nutrients to this region of high, and variable, metabolic demand. Various sources of endogenous ATP have been proposed, including from epithelial, endothelial, and red blood cells in response to stimuli such as mechanical stimulation, local acidosis, hypoxia, and exposure to various hormones. Extensive sympathetic innervation of the nephron has previously been shown, however the innervation reported has focused around the proximal and distal tubules, and ascending loop of Henle. We hypothesize that sympathetic nerves are an additional source of ATP acting at renal pericytes and therefore regulate MBF. Using a rat live kidney slice model in combination with video imaging and confocal microscopy techniques we firstly show sympathetic nerves in close proximity to vasa recta pericytes in both the outer and inner medulla. Secondly, we demonstrate pharmacological stimulation of sympathetic nerves in situ (by tyramine) evokes pericyte-mediated vasoconstriction of vasa recta capillaries; inhibited by the application of the P2 receptor antagonist suramin. Lastly, tyramine-evoked vasoconstriction of vasa recta by pericytes is significantly less than ATP-evoked vasoconstriction. Sympathetic innervation may provide an additional level of functional regulation in the renal medulla that is highly localized. It now needs to be determined under which physiological/pathophysiological circumstances that sympathetic innervation of renal pericytes is important
    • …
    corecore