A scalable data taking system at a test beam for LHC

We propose the installation of a data taking system at a test beam for the simultaneous test of LHC detectors, trigger and readout electronics, together with the development of the supporting architecture in a multiprocessor environment. A strong emphasis is put on a highly modular design, such that new hardware and software developments can be conveniently introduced for training and evaluation. One of the main thrusts of the project will be the modelling and system integration of different readout architectures, which are meant to provide a valuable training ground for new techniques. To address these aspects in a realistic manner, we propose to collaborate with two detector R+D projects

Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kB.

BACKGROUND: Endothelial MAdCAM-1 (mucosal addressin cell adhesion molecule-1) expression is associated with the oxidant-dependent induction and progress of inflammatory bowel disease (IBD). Melatonin, a relatively safe, potent antioxidant, has shown efficacy in several chronic injury models may limit MAdCAM-1 expression and therefore have a therapeutic use in IBD. METHODS: We examined how different doses of melatonin reduced endothelial MAdCAM-1 induced by TNF-a in an in vitro model of lymphatic endothelium. Endothelial monolayers were pretreated with melatonin prior to, and during an exposure, to TNF-a (1 ng/ml, 24 h), and MAdCAM-1 expression measured by immunoblotting. RESULTS: MAdCAM-1 was induced by TNF-a. Melatonin at concentrations over 100 μm (10(-4) M) significantly attenuated MAdCAM-1 expression and was maximal at 1 mM. CONCLUSIONS: Our data indicate that melatonin may exert therapeutic activity in IBD through its ability to inhibit NF-kB dependent induction of MAdCAM-1

The ATLAS Level-1 Calorimeter Trigger

The ATLAS Level-1 Calorimeter Trigger uses reduced-granularity information from all the ATLAS calorimeters to search for high transverse-energy electrons, photons, tau leptons and jets, as well as high missing and total transverse energy. The calorimeter trigger electronics has a fixed latency of about 1 microsecond, using programmable custom-built digital electronics. This paper describes the Calorimeter Trigger hardware, as installed in the ATLAS electronics cavern

A study of multi-jet events at the CERN I3p collider and a search for double patton scattering UA2 Collaboration Bern-Cambridge-CERN-Dortmund-Heidelberg-Melbourne-Milano-Orsay (LAL)-Pavia- Perugia-Pisa-Saclay (CEN)

A study of events containing at least four high transverse momentum jets and a search for double parton scattering (DPS) have been performed using data collected with the UA2 detector at the CERN lbp Collider (x/s= 630 GeV). The results are in good agreement with leading order QCD calculations. A value of at~Ps < 0.82 nb at 95% confidence level (CL) is obtained for the DPS cross section