190 research outputs found
The Stability of an Isotropic Cosmological Singularity in Higher-Order Gravity
We study the stability of the isotropic vacuum Friedmann universe in gravity
theories with higher-order curvature terms of the form
added to the Einstein-Hilbert Lagrangian of general relativity on approach to
an initial cosmological singularity. Earlier, we had shown that, when ,
a special isotropic vacuum solution exists which behaves like the
radiation-dominated Friedmann universe and is stable to anisotropic and small
inhomogeneous perturbations of scalar, vector and tensor type. This is
completely different to the situation that holds in general relativity, where
an isotropic initial cosmological singularity is unstable in vacuum and under a
wide range of non-vacuum conditions. We show that when , although a
special isotropic vacuum solution found by Clifton and Barrow always exists, it
is no longer stable when the initial singularity is approached. We find the
particular stability conditions under the influence of tensor, vector, and
scalar perturbations for general for both solution branches. On approach to
the initial singularity, the isotropic vacuum solution with scale factor
is found to be stable to tensor perturbations for and stable to vector perturbations for , but is
unstable as otherwise. The solution with scale factor
is not relevant to the case of an initial singularity for
and is unstable as for all for each type of perturbation.Comment: 25 page
Symmetric hyperbolic systems for Bianchi equations
We obtain a family of first-order symmetric hyperbolic systems for the
Bianchi equations. They have only physical characteristics: the light cone and
timelike hypersurfaces. In the proof of the hyperbolicity, new positivity
properties of the Bel tensor are used.Comment: latex, 7 pages, accepted for publication in Class. Quantum Gra
Human bronchial fibroblasts express the 5-lipoxygenase pathway
BACKGROUND: Fibroblasts are implicated in sub-epithelial fibrosis in remodeled asthmatic airways and contribute to airway inflammation by releasing cytokines and other mediators. Fibroblast activity is influenced by members of the leukotriene family of bronchoconstrictor and inflammatory mediators, but it is not known whether human bronchial fibroblasts can synthesize leukotrienes. METHODS: The expression of leukotriene biosynthetic enzymes and receptors was investigated in primary fibroblasts from the bronchi of normal and asthmatic adult subjects using RT-PCR, Western blotting, immunocytochemistry and flow cytometry. RESULTS: These techniques revealed that human bronchial fibroblasts from both subject groups constitutively express 5-lipoxygenase, its activating protein FLAP, the terminal enzymes leukotriene A(4 )hydrolase and leukotriene C(4 )synthase, and receptors for leukotriene B(4 )(BLT1) and cysteinyl-leukotrienes (CysLT(1)). Human bronchial fibroblasts generated immunoreactive leukotriene B(4 )and cysteinyl-leukotrienes spontaneously and in increased amounts after calcium-dependent activation. Flow cytometry showed that human bronchial fibroblasts transformed to a myofibroblast-like phenotype by culture with transforming growth factor-β(1 )expressed 320–400% more immunofluorescence for leukotriene C(4 )synthase and CysLT(1 )receptors, with 60–80% reductions in leukotriene A(4 )hydrolase and BLT1 receptors. CONCLUSION: These results indicate that human bronchial fibroblasts may not only respond to exogenous leukotrienes but also generate leukotrienes implicated in narrowing, inflammation and remodeling of the asthmatic airway
The Journal of the Friends' Historical Society vol. 2 No. 3
1. Notices.
2. Notes and Queries.
3. The First Publishers of Truth III.
4. Edmund Peckover, ex-soldier and Quaker.
5. County Tipperary Friends' Records II.
6. Bevan and Naish Library, Birmingham.
7. Decline Literature II.
8. The Price of Candles.
9. Friends on the Atlantic I.
10. Extracts from the Bishop of Chester's Visitation, 1665 I.
11. Meetings in Yorkshire, 1668 III.
12. The Will of Margaret Fox.
13. William Keynell, of Dorsetshire.
14. William Miller at the King's Gardens I.
15. Springett Penn to James Logan.
16. Occurrences for the Progress of Truth I.
17. Friends' in Current Literature.
18. Friends' Reference Library, Devonshire House.
19. Sixth List of Members.
20. Editors' Notes
Twistor geometry of a pair of second order ODEs
We discuss the twistor correspondence between path geometries in three
dimensions with vanishing Wilczynski invariants and anti-self-dual conformal
structures of signature . We show how to reconstruct a system of ODEs
with vanishing invariants for a given conformal structure, highlighting the
Ricci-flat case in particular. Using this framework, we give a new derivation
of the Wilczynski invariants for a system of ODEs whose solution space is
endowed with a conformal structure. We explain how to reconstruct the conformal
structure directly from the integral curves, and present new examples of
systems of ODEs with point symmetry algebra of dimension four and greater which
give rise to anti--self--dual structures with conformal symmetry algebra of the
same dimension. Some of these examples are analogues of plane wave
space--times in General Relativity. Finally we discuss a variational principle
for twistor curves arising from the Finsler structures with scalar flag
curvature.Comment: Final version to appear in the Communications in Mathematical
Physics. The procedure of recovering a system of torsion-fee ODEs from the
heavenly equation has been clarified. The proof of Prop 7.1 has been
expanded. Dedicated to Mike Eastwood on the occasion of his 60th birthda
Complex-Distance Potential Theory and Hyperbolic Equations
An extension of potential theory in R^n is obtained by continuing the
Euclidean distance function holomorphically to C^n. The resulting Newtonian
potential is generated by an extended source distribution D(z) in C^n whose
restriction to R^n is the delta function. This provides a natural model for
extended particles in physics. In C^n, interpreted as complex spacetime, D(z)
acts as a propagator generating solutions of the wave equation from their
initial values. This gives a new connection between elliptic and hyperbolic
equations that does not assume analyticity of the Cauchy data. Generalized to
Clifford analysis, it induces a similar connection between solutions of
elliptic and hyperbolic Dirac equations. There is a natural application to the
time-dependent, inhomogeneous Dirac and Maxwell equations, and the
`electromagnetic wavelets' introduced previously are an example.Comment: 25 pages, submited to Proceedings of 5th Intern. Conf. on Clifford
Algebras, Ixtapa, June 24 - July 4, 199
Lorentzian spin foam amplitudes: graphical calculus and asymptotics
The amplitude for the 4-simplex in a spin foam model for quantum gravity is
defined using a graphical calculus for the unitary representations of the
Lorentz group. The asymptotics of this amplitude are studied in the limit when
the representation parameters are large, for various cases of boundary data. It
is shown that for boundary data corresponding to a Lorentzian simplex, the
asymptotic formula has two terms, with phase plus or minus the Lorentzian
signature Regge action for the 4-simplex geometry, multiplied by an Immirzi
parameter. Other cases of boundary data are also considered, including a
surprising contribution from Euclidean signature metrics.Comment: 30 pages. v2: references now appear. v3: presentation greatly
improved (particularly diagrammatic calculus). Definition of "Regge state"
now the same as in previous work; signs change in final formula as a result.
v4: two references adde
Scattering Amplitudes and BCFW Recursion in Twistor Space
Twistor ideas have led to a number of recent advances in our understanding of
scattering amplitudes. Much of this work has been indirect, determining the
twistor space support of scattering amplitudes by examining the amplitudes in
momentum space. In this paper, we construct the actual twistor scattering
amplitudes themselves. We show that the recursion relations of Britto, Cachazo,
Feng and Witten have a natural twistor formulation that, together with the
three-point seed amplitudes, allows us to recursively construct general tree
amplitudes in twistor space. We obtain explicit formulae for -particle MHV
and NMHV super-amplitudes, their CPT conjugates (whose representations are
distinct in our chiral framework), and the eight particle N^2MHV
super-amplitude. We also give simple closed form formulae for the N=8
supergravity recursion and the MHV and conjugate MHV amplitudes. This gives a
formulation of scattering amplitudes in maximally supersymmetric theories in
which superconformal symmetry and its breaking is manifest. For N^kMHV, the
amplitudes are given by 2n-4 integrals in the form of Hilbert transforms of a
product of purely geometric, superconformally invariant twistor delta
functions, dressed by certain sign operators. These sign operators subtly
violate conformal invariance, even for tree-level amplitudes in N=4 super
Yang-Mills, and we trace their origin to a topological property of split
signature space-time. We develop the twistor transform to relate our work to
the ambidextrous twistor diagram approach of Hodges and of Arkani-Hamed,
Cachazo, Cheung and Kaplan.Comment: v2: minor corrections + extra refs. v3: further minor corrections,
extra discussion of signature issues + more ref
Structure and stability of the Lukash plane-wave spacetime
We study the vacuum, plane-wave Bianchi spacetimes described by
the Lukash metric. Combining covariant with orthonormal frame techniques, we
describe these models in terms of their irreducible kinematical and geometrical
quantities. This covariant description is used to study analytically the
response of the Lukash spacetime to linear perturbations. We find that the
stability of the vacuum solution depends crucially on the background shear
anisotropy. The stronger the deviation from the Hubble expansion, the more
likely the overall linear instability of the model. Our analysis addresses
rotational, shear and Weyl curvature perturbations and identifies conditions
sufficient for the linear growth of these distortions.Comment: Revised version, references added. To appear in Class. Quantum Gra
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