The Jewish 'ghetto': formation and spatial structure

Research into patterns of immigrant settlement has consistently indicated that certain areas of cities are prone to settlement by immigrant groups. This paper proposes that immigrant settlement of such areas may have a particular spacial pattern. Taking the case of the settlement of Leeds, England by Jewish immigrants in the latter six decades of the nineteenth century, we describe the formation of the immigrant Jewish settlement in the area called Leylands.The paper shows first, that Leylands was spacially segregated in comparison with the city overall; and second, that the pattern of settlement was one of intensification of particular streets through time, whereby initially the main, relatively integrated streets were settled, with occupancy moving as time went on to more segregated streets.Analysis of social class defined by occupation suggests that the whole population of Leylands was much poorer than that of Leeds overall. This paper suggests that since the poverty difference was present and possibly more pronounced for the majority, non-Jewish population, that the socio-economic form of the area settlement in Leeds was more likely to have been related to its spacial sgregation than to the social and economic segregation of the immigrant group. It is suggested that the particular characteristics special to certain immigrant groups allowed the Jews of Leylands to overcome their spacial segregation by employing strong social networks on the one hand and through economic mutual help on the other

Development of a surface isolation estimation technique suitable for application of polar orbiting satellite data

A technique is developed for the estimation of total daily insolation on the basis of data derivable from operational polar-orbiting satellites. Although surface insolation and meteorological observations are used in the development, the algorithm is constrained in application by the infrequent daytime polar-orbiter coverage

Near-real-time TOMS, telecommunications and meteorological support for the 1987 Airborne Antarctic Ozone Experiment

The goal of the 1987 Airborne Antarctic Ozone Experiment was to improve the understanding of the mechanisms involved in the formation of the Antarctic ozone hole. Total ozone data taken by the Nimbus-7 Total Ozone Mapping Spectrometer (TOMS) played a central role in the successful outcome of the experiment. During the experiment, the near-real-time TOMS total ozone observations were supplied within hours of real time to the operations center in Punta Arenas, Chile. The final report summarizes the role which Research and Data Systems (RDS) Corporation played in the support of the experiment. The RDS provided telecommunications to support the science and operations efforts for the Airborne Antarctic Ozone Experiment, and supplied near real-time weather information to ensure flight and crew safety; designed and installed the telecommunications network to link NASA-GSFC, the United Kingdom Meteorological Office (UKMO), Palmer Station, the European Center for Medium-Range Weather Forecasts (ECMWF) to the operation at Punta Arenas; engineered and installed stations and other stand-alone systems to collect data from designated low-orbiting polar satellites and beacons; provided analyses of Nimbus-7 TOMS data and backup data products to Punta Arenas; and provided synoptic meteorological data analysis and reduction

The architectural adaptation of urban economic life: Location, use and form of the commercial-residential building in Cardiff

Revisiting Jane Jacob's notion of locality knowledge, this paper argues that combining commercial space and dwelling fosters social, economic and architectural processes that come about by factors of local urban economies. The mixing of uses merges the relation of 'what one does' and 'where one lives' in a particular building whereby urban and architectural scale effects come into place. Comparisons of commercial-residential buildings in two local districts of contrasting morphologies in the city of Cardiff are studied in the context of their urban-architectural design scales. From an urban scale analysis, attention is given to the distribution of commercial-residential buildings in relation to spatial centrality; from an architectural perspective, it examines the way residential building adapts commercial additions, defining how different functions associate distinctive adaptable typologies depending on the building's urban location. By using syntactical and morphological approaches, the paper combines Depth Distance analysis with patterns of use and building form, drawing two reportable findings: The identification of corner shops located within one turn of direction from main high streets within gridiron urban forms, while activities combining retail or local office businesses with residential functions are located in corner blocks along streets within radial urban morphologies. These spatial attributes of location combine the adaptability of local property markets to mixed use with advantages in accessibility to produce an urban building that can flexibly accommodate innovation that is both a reflection of new skills and knowledge contributing to a local diversity

Pepducins as a potential treatment strategy for asthma and COPD.

Current therapies to treat asthma and other airway diseases primarily include anti-inflammatory agents and bronchodilators. Anti-inflammatory agents target trafficking and resident immunocytes and structural cells, while bronchodilators act to prevent or reverse shortening of airway smooth muscle (ASM), the pivotal tissue regulating bronchomotor tone. Advances in our understanding of the biology of G protein-coupled receptors (GPCRs) and biased agonism offers unique opportunities to modulate GPCR function that include the use of pepducins and allosteric modulators. Recent evidence suggests that small molecule inhibitors of Gα q as well as pepducins targeting G q -coupled receptors can broadly inhibit contractile agonist-induced ASM function. Given these advances, new therapeutic approaches can be leveraged to diminish the global rise in morbidity and mortality associated with asthma and chronic obstructive pulmonary disease

Investigation of Lunar Surface Chemical Contamination by LEM Descent Engine and Associated Equipment

Lunar surface and atmospheric contamination study caused by LEM rocket exhaust and inorganic, organic, and microbiological contaminant