944 research outputs found

    Population-based Algorithm Portfolios with automated constituent algorithms selection

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    AbstractPopulation-based Algorithm Portfolios (PAP) is an appealing framework for integrating different Evolutionary Algorithms (EAs) to solve challenging numerical optimization problems. Particularly, PAP has shown significant advantages to single EAs when a number of problems need to be solved simultaneously. Previous investigation on PAP reveals that choosing appropriate constituent algorithms is crucial to the success of PAP. However, no method has been developed for this purpose. In this paper, an extended version of PAP, namely PAP based on Estimated Performance Matrix (EPM-PAP) is proposed. EPM-PAP is equipped with a novel constituent algorithms selection module, which is based on the EPM of each candidate EAs. Empirical studies demonstrate that the EPM-based selection method can successfully identify appropriate constituent EAs, and thus EPM-PAP outperformed all single EAs considered in this work

    Solitary adrenal metastasis from invasive ductal breast cancer: an uncommon finding

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    <p>Abstract</p> <p>Background</p> <p>Invasive ductal carcinoma (IDC) of the breast usually metastasizes to the lungs, liver, bones and brain. Solitary adrenal metastasis is extremely rare. Due to the rarity of this condition, the optimal treatment is unclear. We report the first case of IDC of the breast metastasizing solely to the adrenal gland after a modified radical mastectomy but having a long-term disease-free survival while treated merely by a left adrenalectomy.</p> <p>Case presentation</p> <p>A 64-year-old woman was found a left adrenal mass on a follow- up visit two years after taking a right modified radical mastectomy for the breast cancer. She was subsequently given a left adrenalectomy. Postoperative histopathology findings were compatible with invasive ductal carcinoma (IDC) of the breast. Due to the patient's refusal, no further treatments were offered after the adrenalectomy. The patient now is still alive and has no sign of relapse. Survival time after taking the right modified radical mastectomy and the left adrenalectomy is more than five years and three years, respectively.</p> <p>Conclusion</p> <p>This is the first case of a patient with solitary, metachronous adrenal metastasis from IDC of the breast to be reported. For patients in this condition, complete removal of metastasized organ may translate into survival benefit.</p

    Gamma rays and neutrinos from dark matter annihilation in galaxy clusters

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    The γ\gamma-ray and neutrino emissions from dark matter (DM) annihilation in galaxy clusters are studied. After about one year operation of Fermi-LAT, several nearby clusters are reported with stringent upper limits of GeV γ\gamma-ray emission. We use the Fermi-LAT upper limits of these clusters to constrain the DM model parameters. We find that the DM model distributed with substructures predicted in cold DM (CDM) scenario is strongly constrained by Fermi-LAT γ\gamma-ray data. Especially for the leptonic annihilation scenario which may account for the e±e^{\pm} excesses discovered by PAMELA/Fermi-LAT/HESS, the constraint on the minimum mass of substructures is of the level 102−10310^2-10^3 M⊙_{\odot}, which is much larger than that expected in CDM picture, but is consistent with a warm DM scenario. We further investigate the sensitivity of neutrino detections of the clusters by IceCube. It is found that neutrino detection is much more difficult than γ\gamma-rays. Only for very heavy DM (∼10\sim 10 TeV) together with a considerable branching ratio to line neutrinos the neutrino sensitivity is comparable with that of γ\gamma-rays.Comment: 21 pages, 8 figures and 1 table; extended discussion about the uncertainties of concentration and subhalo models, figures replotted for better read; references updated; accepted for publication by Phys. Rev.

    Synthesis, Structural Characterization, and Catalytic Property of A Zn(II) Complex with 5-Bromosalicylaldehyde Ligand

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    The study on catalytic activity of complex materials has been one of the hot spots in coordination  chemistry. In order to extensively study the catalytic activity of complexes, a new six-coordination Zn(II) complex material, [ZnL2(H2O)2] (C1) (HL = 5-bromosalicylaldehyde), has been prepared with 5-bromosalicylaldehyde, NaOH, and Zn(CH3COO)2·2H2O as raw materials. The structure of C1 was determined by elemental analysis, IR spectra, and single crystal X-ray diffraction. The Zn(II) complex shows a moderate catalytic activity for A3 coupling reaction of benzaldehyde, piperidine, and phenylacetylene with the benzaldehyde conversion reached 54.6 %. Furthermore, the Zn(II) complex catalyst exhibited 54.8 %, 53.8 %, and 54.4 % conversions of benzaldehyde in the second, third, and fourth cycles, respectively.  In addition, the Zn(II) complex features a selectivity of 100 % to the     product of propargylamine for the A3 coupling reaction. Copyright © 2017 BCREC Group. All rights reserved Received: 25th December 2016; Revised: 10th March 2017; Accepted: 10th March 2017; Available online: 273th October 2017; Published regularly: December 2017 How to Cite: Tai, X.S., Li, P.F., Wang, X., Liu, L.L. (2017). Synthesis, Structural Characterization, and Catalytic Property of A Zn(II) Complex with 5-Bromosalicylaldehyde Ligand. Bulletin of Chemical Reaction Engineering & Catalysis, 12(3): 364-369 (doi:10.9767/bcrec.12.3.876.364-369

    Synthesis, Structural Characterization, and Catalytic Property of A Zn(II) Complex with 5-Bromosalicylaldehyde Ligand

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    The study on catalytic activity of complex materials has been one of the hot spots in coordination  chemistry. In order to extensively study the catalytic activity of complexes, a new six-coordination Zn(II) complex material, [ZnL2(H2O)2] (C1) (HL = 5-bromosalicylaldehyde), has been prepared with 5-bromosalicylaldehyde, NaOH, and Zn(CH3COO)2·2H2O as raw materials. The structure of C1 was determined by elemental analysis, IR spectra, and single crystal X-ray diffraction. The Zn(II) complex shows a moderate catalytic activity for A3 coupling reaction of benzaldehyde, piperidine, and phenylacetylene with the benzaldehyde conversion reached 54.6 %. Furthermore, the Zn(II) complex catalyst exhibited 54.8 %, 53.8 %, and 54.4 % conversions of benzaldehyde in the second, third, and fourth cycles, respectively.  In addition, the Zn(II) complex features a selectivity of 100 % to the     product of propargylamine for the A3 coupling reaction.

    Ultra-low-frequency gravitational waves from individual supermassive black hole binaries as standard sirens

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    Ultra-low-frequency gravitational waves (GWs) generated by individual inspiraling supermassive black hole binaries (SMBHBs) in the centers of galaxies may be detected by pulsar timing arrays (PTAs) in the future. These GW signals encoding absolute cosmic distances can serve as bright and dark sirens, having potential to be developed into a precise cosmological probe. Here we show that an SKA-era PTA consisting of 100 millisecond pulsars may observe about 20 bright sirens and 90 dark sirens during a 10-year observation. The bright sirens, together with the CMB data, have comparable capabilities to current mainstream data for measuring the equation of state of dark energy. The dark sirens could make the measurement precision of the Hubble constant far beyond the standard of precision cosmology. Our results indicate that ultra-low-frequency GWs from individual SMBHBs are of great significance in exploring the nature of dark energy and measuring the Hubble constant.Comment: 42 pages, 10 figure

    Population-based Algorithm Portfolios with automated constituent algorithms selection

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    AbstractPopulation-based Algorithm Portfolios (PAP) is an appealing framework for integrating different Evolutionary Algorithms (EAs) to solve challenging numerical optimization problems. Particularly, PAP has shown significant advantages to single EAs when a number of problems need to be solved simultaneously. Previous investigation on PAP reveals that choosing appropriate constituent algorithms is crucial to the success of PAP. However, no method has been developed for this purpose. In this paper, an extended version of PAP, namely PAP based on Estimated Performance Matrix (EPM-PAP) is proposed. EPM-PAP is equipped with a novel constituent algorithms selection module, which is based on the EPM of each candidate EAs. Empirical studies demonstrate that the EPM-based selection method can successfully identify appropriate constituent EAs, and thus EPM-PAP outperformed all single EAs considered in this work
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