Theoretical Study of the Effect of Spray Inclination on Spray Cooling for Large-scale Electronic Equipment

AbstractSpray cooling, as a high efficient and energy-saving cooling method, is expected to be a competitive cooling solution for large-scale electronic device in the future. Lots of theoretical and experimental research on spray cooling has been done till now. But there is rarely integrative study focusing on the influence of the spray inclination change on spray cooling. This paper first deduces in detail the boundary curvilinear equation of the spraying action area with different spray inclination angles and the formula of the actual flow in the target area, then further realizes its algorithm on computers and the comparative analysis of typicalresults. The conclusion will be instructive to the experimental research and the engineering application of the spray cooling

The SH2/SH3 Adaptor Protein Dock Interacts with the Ste20-like Kinase Misshapen in Controlling Growth Cone Motility

AbstractRecent studies suggest that the SH2/SH3 adaptor Dock/Nck transduces tyrosine phosphorylation signals to the actin cytoskeleton in regulating growth cone motility. The signaling cascade linking the action of Dock/Nck to the reorganization of cytoskeleton is poorly understood. We now demonstrate that Dock interacts with the Ste20-like kinase Misshapen (Msn) in the Drosophila photoreceptor (R cell) growth cones. Loss of msn causes a failure of growth cones to stop at the target, a phenotype similar to loss of dock, whereas overexpression of msn induces pretarget growth cone termination. Physical and genetic interactions between Msn and Dock indicate a role for Msn in the Dock signaling pathway. We propose that Msn functions as a key controller of growth cone cytoskeleton in response to Dock-mediated signals

Overexpression of lncRNA UCA1 promotes osteosarcoma progression and correlates with poor prognosis

AbstractLong non-coding RNAs (lncRNAs) have been proved to play important roles in the tumorigenesis and development of several human malignancies. Our study aims to investigate the expression and function of lncRNA-UCA1 in osteosarcoma. lncRNA-UCA1 expression was detected in osteosarcoma tissues and cell lines by using qRT-PCR. Association between lncRNA-UCA1 levels and clinicopathological factors and patient's prognosis was analyzed. The roles of lncRNA-UCA1 in regulating osteosarcoma cell proliferation, apoptosis, migration, and invasion were evaluated in vitro. We found that lncRNA-UCA1 expression was upregulated in osteosarcoma tissues and cell lines. High lncRNA-UCA1 expression was significantly correlated with large tumor size, high tumor grade, positive distant metastasis, and advanced clinical stage. Multivariate regression analysis identified lncRNA-UCA1 overexpression as an independent unfavorable prognostic factor. lncRNA-UCA1 knockdown inhibited osteosarcoma cell proliferation, promoted cell apoptosis, and suppressed cell invasion and migration, whereas lncRNA-UCA1 overexpression showed opposite effects. These findings suggested that lncRNA-UCA1 may contribute to osteosarcoma initiation and progression, and would be not only a novel prognostic marker but also a potential therapeutic target for this disease

A robust agorithm for eye detection on gray intensity face without spectacles

This paper presents a robust eye detection algorithm for gray intensity images. The idea of our method is to combine the respective advantages of two existing techniques, feature based method and template based method, and to overcome their shortcomings. Firstly, after the location of face region is detected, a feature based method will be used to detect two rough regions of both eyes on the face. Then an accurate detection of iris centers will be continued by applying a template based method in these two rough regions. Results of experiments to the faces without spectacles show that the proposed approach is not only robust but also quite efficient.Facultad de Informátic