2,892 research outputs found
Waiting for Their Chance: A Closer Look at Wait Lists in Urban Public Charter Schools
Public charter schools are finally giving parents an alternative to the low-performing school systems in the nation's biggest cities. Unfortunately, in communities with few high-quality public school options, the demand for charter schools is substantially higher than the number of seats available. When this happens, charter schools hold lotteries to determine which students will be able to attend. And every year far too many students end up on wait lists, rather than in the school of their choice. No student's fate should be decided by a lottery ball.This report looks at conditions in ten urban school districts that have large wait lists for public charter schools. In these school districts, nearly all of their traditional public school systems perform well below their state's average, and most of them have public charter schools that are achieving positive academic outcomes for their students. Not surprisingly, these districts also have thousands of students who are waiting for a chance to attend a public charter school
Taking Tasers Seriously: The Need for Better Regulation of Stun Guns in New York
This report analyzes 851 Taser incident reports from eight police departments across the state as well as 10 departments' policies and guidelines for using the weapons, which deliver up to 50,000 volts of electricity and have caused the deaths of more than a dozen New Yorkers in recent years. The report concludes that police officers throughout New York State are consistently misusing and overusing Tasers
Boxed In: The True Cost of Extreme Isolation in New York's Prisons
The NYCLU set out to investigate New York's use of extreme isolation. We explored the history that led to the emergence and expansion of the practice in New York. We asked who New York subjects to extreme isolation, for what reasons, and for how long. We sought to understand and articulate its effects on prisoners and their families, as well as an often-overlooked population -- the corrections staff assigned to watch them. We compared New York's use of extreme isolation with practices in other states and asked if the widespread use of the practice violates legal standards. Finally, we considered how reforming the use of extreme isolation would affect the safety of New York's prisons and communities.In order to answer these questions, the NYCLU conducted an intensive year-long investigation. We communicated with more than 100 prisoners who have spent significant amounts of time -- in one case, more than 20 years -- inside a SHU cell. We interviewed family members and corrections staff. We consulted corrections experts, mental health professionals, lawyers and academics. We read decades of DOCCS reports and press coverage recounting the history of New York's SHU expansion. We researched the scientific and academic literature regarding the use and effects of extreme isolation. We studied domestic and international legal standards governing extreme isolation and the steps undertaken by other states to reform their use of the practice. Finally, we reviewed DOCCS' internal regulations and policies and analyzed thousands of pages of official DOCCS records obtained through New York's open records laws
Targeting extracellular DNA to deliver IGF-1 to the injured heart.
There is a great need for the development of therapeutic strategies that can target biomolecules to damaged myocardium. Necrosis of myocardium during a myocardial infarction (MI) is characterized by extracellular release of DNA, which can serve as a potential target for ischemic tissue. Hoechst, a histological stain that binds to double-stranded DNA can be conjugated to a variety of molecules. Insulin-like growth factor-1 (IGF-1), a small protein/polypeptide with a short circulating-half life is cardioprotective following MI but its clinical use is limited by poor delivery, as intra-myocardial injections have poor retention and chronic systemic presence has adverse side effects. Here, we present a novel delivery vehicle for IGF-1, via its conjugation to Hoechst for targeting infarcted tissue. Using a mouse model of ischemia-reperfusion, we demonstrate that intravenous delivery of Hoechst-IGF-1 results in activation of Akt, a downstream target of IGF-1 and protects from cardiac fibrosis and dysfunction following MI
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