2,248 research outputs found
Evolution of a scenario-based method in development of requirements for a ubiquitous and cross platform e-learning environment
A dual device scenario for informal language learning: interactive television meets the mobile phone
Copper Mining and Environmental Costs in Dominica
A proposal from an international mining company to establish a copper mining operation in the Caribbean island of Dominica could be highly favourable, given the potential for financial benefits associated with such a project. On the downside, such projects are often associated with environmental damage. The area targeted for this copper mine was a rainforest in the north-eastern portion of Dominica occupying around 12 percent of the islandâs total land area. A critical question is therefore whether copper mining could be a viable alternative to agrarian uses of the targeted area, if both financial and environmental costs are taken into consideration. A Contingent Valuation Survey of Dominicans and Visitors allowed for inclusion of non-market costs in the analysis. Cost-Benefit and sensitivity analyses were carried out to assess project feasibility. The results indicated that NPV was negative under conservative assumptions. NPV was sensitive to changes in the price of copper and the inclusion of environmental costs did affect the level of price increase required to make NPV positive.Copper mining, Dominica, environmental costs, sensitivity analysis, cost-benefit, Agribusiness, Environmental Economics and Policy, Financial Economics,
Similar Souls on the Journey : Meaning-Making in a Contemplative Community of Faculty of Color
This paper highlights the meaning, both personal and professional, made by participants in a community of faculty of color, with a focus on contemplative practices and pedagogy
Breastfeeding as Activism: Moving from Oppression to Emancipation
Women have a long history of oppression. Despite making great strides towards equality, some mothers find their experience of breastfeeding oppressive. Mothers who experience oppression related to breastfeeding may become emancipated and engage in breastfeeding activism
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Case report: targeted whole exome sequencing enables the first prenatal diagnosis of the lethal skeletal dysplasia Osteocraniostenosis.
BACKGROUND: Osteocraniostenosis (OCS) is a rare genetic disorder characterised by premature closure of cranial sutures, gracile bones and perinatal lethality. Previously, diagnosis has only been possible postnatally on clinical and radiological features. This study describes the first prenatal diagnosis of OCS. CASE PRESENTATION: In this case prenatal ultrasound images were suggestive of a serious but non-lethal skeletal dysplasia. Due to the uncertain prognosis the parents were offered Whole Exome Sequencing (WES), which identified a specific gene mutation in the FAMIIIa gene. This mutation had previously been detected in two cases and was lethal in both perinatally. This established the diagnosis, a clear prognosis and allowed informed parental choice regarding ongoing pregnancy management. CONCLUSIONS: This case report supports the use of targeted WES prenatally to confirm the underlying cause and prognosis of sonographically suspected abnormalities
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