The carbon-saving behaviour of residential households

The housing sector in 2004 was accountable for about 30% of total UK carbon emissions. The magnitude of this figure represents a significant imperative for policymakers to act on the sector through behavioural change strategies. Energy efficiency in households might easily be considered as driven mainly by economic motives, but this would not explain why even cost-free behavioural changes, like switching the lights off more often, are not adopted more widely. Literature has mainly concentrated either on the economic motives of pro-environmental behaviours or on the relevance of attitudes to shape them. Little has been said so far on the interaction between attitudes and the so called contextual factors. Diekmann and Presindörfer (2003) outlined the “low-cost hypothesis” which argues that pro-environmental behaviours are driven by pro-environmental attitudes only in the presence of low costs. However, little is known about households’ perceptions of costs and benefits in relation to energy saving behaviour. We propose to develop the low-cost hypothesis with a theoretical approach integrating attitudinal research and rational choice literature and explaining the interaction between tangible and intangible costs and benefits.Furthermore, the importance of resources such as education, information and income is highlighted in order to explain the magnitude of the perception of the costs and benefits considered by households. Finally, the scope for policy intervention aimed at shaping perceived costs and benefits to help the drive towards pro-environmental behaviour is discussed

Impaired immunogenicity to COVID-19 vaccines in autoimmune systemic diseases. High prevalence of non-response in different patients’ subgroups

Autoimmune systemic diseases (ASD) may show impaired immunogenicity to COVID-19 vaccines. Our prospective observational multicenter study aimed to evaluate the seroconversion after the vaccination cycle and at 6-12-month follow-up, as well the safety and efficacy of vaccines in preventing COVID-19. The study included 478 unselected ASD patients (mean age 59 ± 15 years), namely 101 rheumatoid arthritis (RA), 38 systemic lupus erythematosus (SLE), 265 systemic sclerosis (SSc), 61 cryoglobulinemic vasculitis (CV), and a miscellanea of 13 systemic vasculitis. The control group included 502 individuals from the general population (mean age 59 ± 14SD years). The immunogenicity of mRNA COVID-19 vaccines (BNT162b2 and mRNA-1273) was evaluated by measuring serum IgG-neutralizing antibody (NAb) (SARS-CoV-2 IgG II Quant antibody test kit; Abbott Laboratories, Chicago, IL) on samples obtained within 3 weeks after vaccination cycle. The short-term results of our prospective study revealed significantly lower NAb levels in ASD series compared to controls [286 (53–1203) vs 825 (451–1542) BAU/mL, p < 0.0001], as well as between single ASD subgroups and controls. More interestingly, higher percentage of non-responders to vaccine was recorded in ASD patients compared to controls [13.2% (63/478), vs 2.8% (14/502); p < 0.0001]. Increased prevalence of non-response to vaccine was also observed in different ASD subgroups, in patients with ASD-related interstitial lung disease (p = 0.009), and in those treated with glucocorticoids (p = 0.002), mycophenolate-mofetil (p < 0.0001), or rituximab (p < 0.0001). Comparable percentages of vaccine-related adverse effects were recorded among responder and non-responder ASD patients. Patients with weak/absent seroconversion, believed to be immune to SARS-CoV-2 infection, are at high risk to develop COVID-19. Early determination of serum NAb after vaccination cycle may allow to identify three main groups of ASD patients: responders, subjects with suboptimal response, non-responders. Patients with suboptimal response should be prioritized for a booster-dose of vaccine, while a different type of vaccine could be administered to non-responder individuals

POS1246 COVID-19 IN ITALIAN PATIENTS WITH RHEUMATIC AUTOIMMUNE SYSTEMIC DISEASES: RESULTS OF A NATIONWIDE SURVEY STUDY

Background: SARS-CoV-2 infection poses a serious challenge for patients with rheumatic autoimmune systemic diseases (ASD), characterized by marked immune-system dysregulation and frequent visceral organ involvement. Objectives: To evaluate the impact of Covid-19 pandemic in a large series of Italian patients with ASD. Methods: Our multicenter telephone survey (8-week period, March-April 2020) included a large series of 2,994 patients (584 M, 2,410 F, mean age 58.9±13.4SD years) with ASD followed at 34 tertiary referral centers of 14 regions of northern, central, and southern Italian macro areas, characterized by different prevalence of SARS-CoV-2 infection. According to currently used criteria, Covid-19 was classified as definite Covid-19 (signs or symptoms of Covid-19 confirmed by positive oral/nasopharyngeal swabs at PCR testing) or highly suspected Covid-19 (signs or symptoms highly

Delivering a Timely and Just Energy Transition: Which Policy Research Priorities?

In recent years, the concept of“energy justice”has attracted much attention andresearch effort. Although all policy issues related to energy justice are worthy of furtherstudy, the time constraints posed by the looming threat of climate change suggests theneed for coordinated policy research efforts. At the current stage of development ofEuropean societies, we consider that four policy research strands might be most impor-tant in the light of specific evolving trendsof European energy systems. Therefore, wepropose these priorities as a shared researchagenda for academic and policy researchers.In this article, we develop and discuss thefollowing four research priority strands:(a) intergenerational justice and energy justice, (b) justice and energy vulnerability,(c) transformation of the social imaginary and energy infrastructure, and (d) damage, com-pensation, and energy infrastructure. For each topic, we highlight their critical issues andresearch opportunities. We conclude that these priorities are necessary not only to accel-erate the energy transition but also to avoid negative impacts that climate change andthe transition phase could produce on already established patterns of inequality

Exercise-induced intravascular haemolysis in standardbred horses

In human sports medicine a pathophysiological condition called 'sports anaemia' is reported. This condition has been attributed to episodes of intravascular haemolysis induced by physical exercise. The occurrence of haemolytic episodes is indicated by the presence of high values of free plasma haemoglobin and lower plasma levels of haptoglobin after physical exercise. The literature regarding sports anaemia in horses, and in particular haemolysis induced by physical exercise, is rather limited. The purpose of this study was to evaluate the markers of intravascular haemolysis (plasma haemoglobin and haptoglobin) in Standardbred horses immediately after a race, in order to ascertain the presence of intravascular haemolysis, possibly induced by physical activity. We reported both the haptoglobin and free plasma haemoglobin values as a percentage of the total protein to avoid any influence of haemoconcentration induced by the exertion during the race. Free plasma haemoglobin concentration showed a significant increase both at 5 min (p < 0.01) and 10 min (p < 0.05) after exercise. A significant decrease in the haptoglobin occurred in both post-exercise blood samples, and was statistically significant 10 min after the race (p < 0.05). These data suggested that episodes of intravascular haemolysis may occur during physical activity in Standardbred horses