175 research outputs found

    China and Climate Change : Exploring a Non-Western Climate Discourse

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    In recent years, addressing climate change has become a top priority of China’s national agenda. There has been a rich body of literature studying China’s position in climate policies and negotiations. However, a detailed analysis of the symbolic meaning and internal diversity of its position is lacking. This paper analyzes these issues through a discourse and strategic narrative lens, examining the connotations, characteristics, and construction of China’s climate discourse. Four climate discourses in China are identified: pragmatic ecological modernization, climate nationalism, ecological civilization, and collaborative civil environmentalism. These discourses are consistent with China’s national policy as well as its global vision. The dynamics of discourse adaptation, localization, integration, and innovation in the process of their construction, seen against the complex and changing domestic and international context, highlight the identitybased and issue-based strategic narratives. China provides a good example of a “non-Western” climate discourse that demonstrates an emerging country’s interests and climate practices , and offers the possibility of breaking the North-South impasse in global climate politics. This paper concludes that climate change is an important entry point for China to gain greater influence on global governance through implicit discursive strategies.投稿論文Refereed Articl

    磁性粘弾性材料を用いた柔軟なアクチュエーションシステムの開発

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    早大学位記番号:新9135早稲田大

    Gate-controlled reversible rectifying behaviour in tunnel contacted atomically-thin MoS2_{2} transistor

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    Atomically-thin 2D semiconducting materials integrated into van der Waals heterostructures have enabled architectures that hold great promise for next generation nanoelectronics. However, challenges still remain to enable their full acceptance as compliant materials for integration in logic devices. Two key-components to master are the barriers at metal/semiconductor interfaces and the mobility of the semiconducting channel, which endow the building-blocks of pn{pn} diode and field effect transistor. Here, we have devised a reverted stacking technique to intercalate a wrinkle-free h-BN tunnel layer between MoS2_{2} channel and contacting electrodes. Vertical tunnelling of electrons therefore makes it possible to suppress the Schottky barriers and Fermi level pinning, leading to homogeneous gate-control of the channel chemical potential across the bandgap edges. The observed unprecedented features of ambipolar pn{pn} to np{np} diode, which can be reversibly gate tuned, paves the way for future logic applications and high performance switches based on atomically thin semiconducting channel.Comment: 23 pages, 5 main figures + 9 SI figure

    Le regole del gioco: Primo incontro con l'ingegneria strategica

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    Cu particles decorated carbon composite microspheres (CCMs) with a unique sesame ball structure have been prepared by combining the mass-producible spray drying technique with calcinations. The conventional cuprammonium cellulose complex solution obtained by dissolving cellulose in a cuprammonia solution has been applied as raw materials for the preparation of Cu­(NH<sub>3</sub>)<sub>4</sub><sup>2+</sup>/cellulose complex microspheres via a spray drying process. The resulted Cu­(NH<sub>3</sub>)<sub>4</sub><sup>2+</sup>/cellulose complex microspheres are then transformed into the Cu particles homogeneously decorated porous carbon spheres <i>in situ</i> by calcinations at 450 or 550 °C. The coordination effect between the Cu­(NH<sub>3</sub>)<sub>4</sub><sup>2+</sup> species and the hydroxyl groups of the cellulose macromolecules has been exploited for directing the dispersion of the Cu particles in the resultant composite CCMs. The antimicrobial effects of the CCMs are evaluated by determining the minimum growth inhibitory concentrations using Staphylococcus aureus and Escherichia coli as representatives, respectively. The CCMs show high efficiency catalytic properties to the conversion of 4-nitrophenol to 4-aminophenol using NaBH<sub>4</sub> as a reductant in a mild condition. The recyclability and stability of the CCM catalysts have also been studied

    High C1QTNF1 expression mediated by potential ncRNAs is associated with poor prognosis and tumor immunity in kidney renal clear cell carcinoma

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    Background: Kidney renal clear cell carcinoma (KIRC) originates from proximal tubular cells and is the most common subtype of renal cell carcinoma. KIRC is characterized by changes in lipid metabolism, and obesity is a risk factor for it. C1q And TNF Related 1 (C1QTNF1), a novel adipokine and member of the C1q and TNF-related protein (CTRP) family, has been shown to affect the progression of various cancers. However, the role of C1QTNF1 in KIRC has not been studied.Methods: The Wilcoxon rank sum test was used to analyze the expression of C1QTNF1 in KIRC tissues and normal tissues. The relationship between clinicopathological features and C1QTNF1 levels was also examined by logistic regression and the Wilcoxon rank sum test. In addition, the effect of C1QTNF1 on the prognosis of KIRC patients was analyzed by Kaplan-Meier (KM). The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were used to analyze the potential signaling pathways and biological functions of differential genes. A nomogram was constructed to predict the prognosis of KIRC patients. Spearman correlation analysis was performed to determine the association between C1QTNF1 expression and immune cell infiltration and immune checkpoint genes. The upstream miRNAs and lncRNAs of C1QTNF1 were predicted by the ENCORI online tool. Finally, we examined the proliferation, invasion, and migration abilities of KIRC cells after C1QTNF1 knockdown.Results: The expression of C1QTNF1 in KIRC tissues was significantly higher than in normal renal tissues. Patients with higher C1QTNF1 expression had a poor prognosis, a finding supported by Kaplan-Meier survival analysis. C1QTNF1 expression was significantly correlated with TNM and pathologic stages, age, and gender (p &lt; 0.05). The C1QTNF1 expression level was significantly correlated with immune cell infiltration and immune checkpoint genes in KIRC. Additionally, high C1QTNF1 expression was associated with poor prognosis in stage I and II, T1 and T2, T3 and T4, N0, and M0 patients (HR &gt; 1, p &lt; 0.05). The calibration diagram shows that the C1QTNF1 model has effective predictive performance for the survival of KIRC patients. Knockdown of C1QTNF1 inhibited KIRC cell proliferation, cell migration, and cell invasion. In addition, CYTOR and AC040970.1/hsa-miR-27b-3p axis were identified as the most likely upstream ncRNA-related pathways of C1QTNF1 in KIRC.Conclusion: In conclusion, our study suggests that high expression of C1QTNF1 is associated with KIRC progression and immune infiltration. The increased expression of C1QTNF1 suggests a poor prognosis in KIRC patients

    Loss of BMP signaling through BMPR1A in osteoblasts leads to greater collagen cross-link maturation and material-level mechanical properties in mouse femoral trabecular compartments

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    Bone morphogenetic protein (BMP) signaling pathways play critical roles in skeletal development and new bone formation. Our previous study, however, showed a negative impact of BMP signaling on bone mass because of the osteoblast-specific loss of a BMP receptor (i.e. BMPR1A) showing increased trabecular bone volume and mineral density in mice. Here, we investigated the bone quality and biomechanical properties of the higher bone mass associated with BMPR1A deficiency using the osteoblast-specific Bmpr1a conditional knockout (cKO) mouse model. Collagen biochemical analysis revealed greater levels of the mature cross-link pyridinoline in the cKO bones, in parallel with upregulation of collagen modifying enzymes. Raman spectroscopy distinguished increases in the mature to immature cross-link ratio and mineral to matrix ratio in the trabecular compartments of cKO femora, but not in the cortical compartments. The mineral crystallinity was unchanged in the cKO in either the trabecular or cortical compartments. Further, we tested the intrinsic material properties by nanoindentation and found significantly higher hardness and elastic modulus in the cKO trabecular compartments, but not in the cortical compartments. Four point bending tests of cortical compartments showed lower structural biomechanical properties (i.e. strength and stiffness) in the cKO bones due to the smaller cortical areas. However, there were no significant differences in biomechanical performance at the material level, which was consistent with the nanoindentation test results on the cortical compartment. These studies emphasize the pivotal role of BMPR1A in the determination of bone quality and mechanical integrity under physiological conditions, with different impact on femoral cortical and trabecular compartments

    Review of dynamic modelling, system identification and control scheme in solvent-based post-combustion carbon capture process

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    Solvent-based post-combustion carbon capture (PCC) process is widely viewed as the most viable option for reducing CO 2 emission. This technology has been deployed globally and many researches have been conducted in this area. In this paper, current status of dynamic modelling, system identification and control scheme of solvent-based PCC process is reviewed. Different research directions of these areas are discussed to conclude the existing challenges. Based on this, this paper is also trying to provide potential solutions as possible pathways for flexible and economical operation

    Femoral–tibial contact stresses on fixed rotational femur models

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    ObjectivesThis study aims to quantitatively evaluate the femoral–tibial contact pressure on the knee under certain malrotaional degrees.MethodsFemoral–tibial contact pressure was carried out on 14 fixed rotational knee models under 200/400/600 N vertical load using ultra-low-pressure sensitive film technology, rotation angles including neutral position (0°, anatomically reduced), 5°, 10°, and 15° internally and externally. Data were collected and analyzed with SPSS software.ResultsThere are significant statistical differences between the medial contact pressure among rotational deformities (including neutral position) (P &lt; 0.01), the increase in the degree of fixed internal malrotation of the femur resulted in a linear increase in the medial femoral–tibial contact pressures (P &lt; 0.05) under 200/400/600 N vertical load, while increase in the degree of fixed external malrotation resulted in a linear decrease (P &lt; 0.05). Except the 200 N compression, we can't find significant differences in lateral contact pressures (P &gt; 0.05). In the comparison of medial to lateral contact pressures, no statistically significant differences were found in neutral and 5° internal rotation under 200/400 N, neutral, 5° internal rotation, and 15° external rotation under 600 N. In contrast, medial contact pressures were higher than lateral at other angles (P &lt; 0.05).ConclusionObvious contact pressure changes were observed in rotatory femur. Doctors should detect rotational deformity as much as possible during operation and perform anatomical reduction. For patients with residual rotational deformities, indication of osteotomy should not be too broad
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