8,048 research outputs found
Oxidation Resistance of Thermal Barrier Coatings Based on Hollow Alumina Particles
International audienc
Rompimiento de la Simetria Electrodebil y la Fisica del Higgs: Conceptos Basicos
Presentamos una introduccion a los conceptos basicos del rompimiento de la
simetria electrodebil y la fisica del Higgs dentro del Modelo Estandar y sus
extensiones supersimetricas. Se presenta tambien una breve perspectiva general
de mecanismos alternativos del rompimiento de la simetria. Ademas de las bases
teoricas, se discute el estado actual de la fisica experimental del Higgs y sus
implicaciones para futuros experimentos en el LHC y en colisionadores lineales
e+e-.Comment: Spanish text, including full English translation. Published in the
Proceedings of the XI Mexican School on Particles and Fields, Xalapa,
Veracruz, Mexic
Genetic noise control via protein oligomerization
Gene expression in a cell entails random reaction events occurring over
disparate time scales. Thus, molecular noise that often results in phenotypic
and population-dynamic consequences sets a fundamental limit to biochemical
signaling. While there have been numerous studies correlating the architecture
of cellular reaction networks with noise tolerance, only a limited effort has
been made to understand the dynamic role of protein-protein interactions. Here
we have developed a fully stochastic model for the positive feedback control of
a single gene, as well as a pair of genes (toggle switch), integrating
quantitative results from previous in vivo and in vitro studies. We find that
the overall noise-level is reduced and the frequency content of the noise is
dramatically shifted to the physiologically irrelevant high-frequency regime in
the presence of protein dimerization. This is independent of the choice of
monomer or dimer as transcription factor and persists throughout the multiple
model topologies considered. For the toggle switch, we additionally find that
the presence of a protein dimer, either homodimer or heterodimer, may
significantly reduce its random switching rate. Hence, the dimer promotes the
robust function of bistable switches by preventing the uninduced (induced)
state from randomly being induced (uninduced). The specific binding between
regulatory proteins provides a buffer that may prevent the propagation of
fluctuations in genetic activity. The capacity of the buffer is a non-monotonic
function of association-dissociation rates. Since the protein oligomerization
per se does not require extra protein components to be expressed, it provides a
basis for the rapid control of intrinsic or extrinsic noise
Potential-density pairs for axisymmetric galaxies: the influence of scalar fields
We present a formulation for potential-density pairs to describe axisymmetric
galaxies in the Newtonian limit of scalar-tensor theories of gravity. The
scalar field is described by a modified Helmholtz equation with a source that
is coupled to the standard Poisson equation of Newtonian gravity. The net
gravitational force is given by two contributions: the standard Newtonian
potential plus a term stemming from massive scalar fields. General solutions
have been found for axisymmetric systems and the multipole expansion of the
Yukawa potential is given. In particular, we have computed potential-density
pairs of galactic disks for an exponential profile and their rotation curves.Comment: 8 pages, no figures, corrected version to the one that will appear in
Gen. Relativ. Gravit., where a small typo in eq. (13) is presen
Valor nutritivo de las fracciones solubles e insolubles del follaje de Gliricidia sepium (Jacq.) Kunth ex Walp
Nutritional potential of water-soluble and water non-soluble leafage of Gliricidia sepium, tested by ruminant degradability and in vitro gas production techniques, was studied.
Ruminant degradability of dry matter and nitrogen showed high values, i.e., 54,5 to
81,9 % and 73,2 to 92,1 %respectively. Lower values were registered in leafage with an older rebudding age or stem inclusion. Both water-soluble and water-nonsoluble leafage are nutritionally relevant. Water-soluble leafage nutritional contribution was higher during the first twelve-hour fermentation process. G. sepium leafage nutritional potential derives from its gradual nitrogen and energy supply to rumen micro-organisms.Se caracterizó la contribución nutritiva de las fracciones solubles e insolubles de diferentes follajes de G. sepium, medidos con las técnicas de degradabilidad ruminal y de producción de gas in vitro. Los potenciales de degradabilidad ruminal de la materia seca (entre 54,5 y 81,9 %) y el nitrógeno (entre 73,2 y 92,1 %) se pueden considerar altos. Los valores menores se alcanzan en follajes con mayores edades de rebrote y con inclusión de tallos. Tanto la fracción soluble como insoluble en agua realizan una importante contribución nutritiva; en las primeras 12 horas de fermentación la fracción soluble hace su mayor aporte. El valor nutritivo del follaje de G. sepium radica, fundamentalmente, en su aporte gradual de nitrógeno y energía a los microorganismos del rumen
Upper Limits on a Stochastic Background of Gravitational Waves
The Laser Interferometer Gravitational-Wave Observatory has performed a third science run with much improved sensitivities of all three interferometers. We present an analysis of approximately 200 hours of data acquired during this run, used to search for a stochastic background of gravitational radiation. We place upper bounds on the energy density stored as gravitational radiation for three different spectral power laws. For the flat spectrum, our limit of Ω_0<8.4×10^(-4) in the 69–156 Hz band is ~10^5 times lower than the previous result in this frequency range
The Gluonic Field of a Heavy Quark in Conformal Field Theories at Strong Coupling
We determine the gluonic field configuration sourced by a heavy quark
undergoing arbitrary motion in N=4 super-Yang-Mills at strong coupling and
large number of colors. More specifically, we compute the expectation value of
the operator tr[F^2+...] in the presence of such a quark, by means of the
AdS/CFT correspondence. Our results for this observable show that signals
propagate without temporal broadening, just as was found for the expectation
value of the energy density in recent work by Hatta et al. We attempt to shed
some additional light on the origin of this feature, and propose a different
interpretation for its physical significance. As an application of our general
results, we examine when the quark undergoes oscillatory motion,
uniform circular motion, and uniform acceleration. Via the AdS/CFT
correspondence, all of our results are pertinent to any conformal field theory
in 3+1 dimensions with a dual gravity formulation.Comment: 1+38 pages, 16 eps figures; v2: completed affiliation; v3: corrected
typo, version to appear in JHE
Limits on Gravitational-Wave Emission from Selected Pulsars Using LIGO Data
We place direct upper limits on the amplitude of gravitational waves from 28 isolated radio pulsars by a coherent multidetector analysis of the data collected during the second science run of the LIGO interferometric detectors. These are the first direct upper limits for 26 of the 28 pulsars. We use coordinated radio observations for the first time to build radio-guided phase templates for the expected gravitational-wave signals. The unprecedented sensitivity of the detectors allows us to set strain upper limits as low as a few times 10^(-24). These strain limits translate into limits on the equatorial ellipticities of the pulsars, which are smaller than 10^(-5) for the four closest pulsars
Low-energy effects in brane worlds: Liennard-Wiechert potentials and Hydrogen Lamb shift
Testing extra dimensions at low-energies may lead to interesting effects. In
this work a test point charge is taken to move uniformly in the 3-dimensional
subspace of a (3+)-brane embedded in a (3++1)-space with compact and
one warped infinite spatial extra dimensions. We found that the electromagnetic
potentials of the point charge match standard Liennard-Wiechert's at large
distances but differ from them close to it. These are finite at the position of
the charge and produce finite self-energies. We also studied a localized
Hydrogen atom and take the deviation from the standard Coulomb potential as a
perturbation. This produces a Lamb shift that is compared with known
experimental data to set bounds for the parameter of the model. This work
provides details and extends results reported in a previous Letter.Comment: Manuscript (LaTeX) and 2 figure files (eps format) used by the
manuscript LaTeX fil
Garlic's ability to prevent in vitro Cu(2+)-induced lipoprotein oxidation in human serum is preserved in heated garlic: effect unrelated to Cu(2+)-chelation
BACKGROUND: It has been shown that several extracts and compounds derived from garlic are able to inhibit Cu(2+)-induced low density lipoprotein oxidation. In this work we explored if the ability of aqueous garlic extract to prevent in vitro Cu(2+)-induced lipoprotein oxidation in human serum is affected by heating (a) aqueous garlic extracts or (b) garlic cloves. In the first case, aqueous extract of raw garlic and garlic powder were studied. In the second case, aqueous extract of boiled garlic cloves, microwave-treated garlic cloves, and pickled garlic were studied. It was also studied if the above mentioned preparations were able to chelate Cu(2+). METHODS: Cu(2+)-induced lipoprotein oxidation in human serum was followed by the formation of conjugated dienes at 234 nm and 37°C by 240 min in a phosphate buffer 20 mM, pH 7.4. Blood serum and CuSO(4 )were added to a final concentration of 0.67% and 0.0125 mM, respectively. The lag time and the area under the curve from the oxidation curves were obtained. The Cu(2+)-chelating properties of garlic extracts were assessed using an approach based upon restoring the activity of xanthine oxidase inhibited in the presence of 0.050 mM Cu(2+). The activity of xanthine oxidase was assessed by monitoring the production of superoxide anion at 560 nm and the formation of uric acid at 295 nm. Data were compared by parametric or non-parametric analysis of variance followed by a post hoc test. RESULTS: Extracts from garlic powder and raw garlic inhibited in a dose-dependent way Cu(2+)-induced lipoprotein oxidation. The heating of garlic extracts or garlic cloves was unable to alter significantly the increase in lag time and the decrease in the area under the curve observed with the unheated garlic extracts or raw garlic. In addition, it was found that the garlic extracts were unable to chelate Cu(2+). CONCLUSIONS: (a) the heating of aqueous extracts of raw garlic or garlic powder or the heating of garlic cloves by boiling, microwave or pickling do not affect garlic's ability to inhibit Cu(2+)-induced lipoprotein oxidation in human serum, and (b) this ability is not secondary to Cu(2+)-chelation
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