8,048 research outputs found

    Oxidation Resistance of Thermal Barrier Coatings Based on Hollow Alumina Particles

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    Rompimiento de la Simetria Electrodebil y la Fisica del Higgs: Conceptos Basicos

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    Presentamos una introduccion a los conceptos basicos del rompimiento de la simetria electrodebil y la fisica del Higgs dentro del Modelo Estandar y sus extensiones supersimetricas. Se presenta tambien una breve perspectiva general de mecanismos alternativos del rompimiento de la simetria. Ademas de las bases teoricas, se discute el estado actual de la fisica experimental del Higgs y sus implicaciones para futuros experimentos en el LHC y en colisionadores lineales e+e-.Comment: Spanish text, including full English translation. Published in the Proceedings of the XI Mexican School on Particles and Fields, Xalapa, Veracruz, Mexic

    Genetic noise control via protein oligomerization

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    Gene expression in a cell entails random reaction events occurring over disparate time scales. Thus, molecular noise that often results in phenotypic and population-dynamic consequences sets a fundamental limit to biochemical signaling. While there have been numerous studies correlating the architecture of cellular reaction networks with noise tolerance, only a limited effort has been made to understand the dynamic role of protein-protein interactions. Here we have developed a fully stochastic model for the positive feedback control of a single gene, as well as a pair of genes (toggle switch), integrating quantitative results from previous in vivo and in vitro studies. We find that the overall noise-level is reduced and the frequency content of the noise is dramatically shifted to the physiologically irrelevant high-frequency regime in the presence of protein dimerization. This is independent of the choice of monomer or dimer as transcription factor and persists throughout the multiple model topologies considered. For the toggle switch, we additionally find that the presence of a protein dimer, either homodimer or heterodimer, may significantly reduce its random switching rate. Hence, the dimer promotes the robust function of bistable switches by preventing the uninduced (induced) state from randomly being induced (uninduced). The specific binding between regulatory proteins provides a buffer that may prevent the propagation of fluctuations in genetic activity. The capacity of the buffer is a non-monotonic function of association-dissociation rates. Since the protein oligomerization per se does not require extra protein components to be expressed, it provides a basis for the rapid control of intrinsic or extrinsic noise

    Potential-density pairs for axisymmetric galaxies: the influence of scalar fields

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    We present a formulation for potential-density pairs to describe axisymmetric galaxies in the Newtonian limit of scalar-tensor theories of gravity. The scalar field is described by a modified Helmholtz equation with a source that is coupled to the standard Poisson equation of Newtonian gravity. The net gravitational force is given by two contributions: the standard Newtonian potential plus a term stemming from massive scalar fields. General solutions have been found for axisymmetric systems and the multipole expansion of the Yukawa potential is given. In particular, we have computed potential-density pairs of galactic disks for an exponential profile and their rotation curves.Comment: 8 pages, no figures, corrected version to the one that will appear in Gen. Relativ. Gravit., where a small typo in eq. (13) is presen

    Valor nutritivo de las fracciones solubles e insolubles del follaje de Gliricidia sepium (Jacq.) Kunth ex Walp

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    Nutritional potential of water-soluble and  water  non-soluble leafage of Gliricidia sepium, tested by ruminant  degradability  and  in  vitro gas production  techniques,  was studied. Ruminant  degradability  of  dry  matter   and  nitrogen  showed high  values,  i.e.,  54,5  to 81,9 % and  73,2  to 92,1 %respectively. Lower values were  registered in leafage with an older rebudding age  or stem  inclusion. Both water-soluble and  water-nonsoluble leafage are  nutritionally relevant. Water-soluble leafage nutritional contribution was higher during the   first  twelve-hour  fermentation  process.  G.  sepium  leafage  nutritional  potential derives from its gradual nitrogen and energy supply to rumen  micro-organisms.Se   caracterizó  la  contribución  nutritiva  de   las  fracciones  solubles  e  insolubles  de diferentes   follajes de G. sepium, medidos con las técnicas de degradabilidad ruminal y de  producción de  gas in vitro. Los potenciales de  degradabilidad ruminal de  la materia seca (entre  54,5  y 81,9 %) y el  nitrógeno  (entre  73,2  y 92,1 %) se pueden considerar altos.  Los valores  menores se alcanzan  en  follajes  con  mayores edades de  rebrote y con  inclusión de  tallos. Tanto  la fracción soluble como  insoluble en  agua realizan una importante contribución nutritiva; en  las primeras 12 horas de  fermentación la fracción soluble hace su mayor  aporte. El valor nutritivo del follaje de G. sepium radica, fundamentalmente, en su aporte gradual de nitrógeno y energía a los microorganismos del rumen

    Upper Limits on a Stochastic Background of Gravitational Waves

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    The Laser Interferometer Gravitational-Wave Observatory has performed a third science run with much improved sensitivities of all three interferometers. We present an analysis of approximately 200 hours of data acquired during this run, used to search for a stochastic background of gravitational radiation. We place upper bounds on the energy density stored as gravitational radiation for three different spectral power laws. For the flat spectrum, our limit of Ω_0<8.4×10^(-4) in the 69–156 Hz band is ~10^5 times lower than the previous result in this frequency range

    The Gluonic Field of a Heavy Quark in Conformal Field Theories at Strong Coupling

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    We determine the gluonic field configuration sourced by a heavy quark undergoing arbitrary motion in N=4 super-Yang-Mills at strong coupling and large number of colors. More specifically, we compute the expectation value of the operator tr[F^2+...] in the presence of such a quark, by means of the AdS/CFT correspondence. Our results for this observable show that signals propagate without temporal broadening, just as was found for the expectation value of the energy density in recent work by Hatta et al. We attempt to shed some additional light on the origin of this feature, and propose a different interpretation for its physical significance. As an application of our general results, we examine when the quark undergoes oscillatory motion, uniform circular motion, and uniform acceleration. Via the AdS/CFT correspondence, all of our results are pertinent to any conformal field theory in 3+1 dimensions with a dual gravity formulation.Comment: 1+38 pages, 16 eps figures; v2: completed affiliation; v3: corrected typo, version to appear in JHE

    Limits on Gravitational-Wave Emission from Selected Pulsars Using LIGO Data

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    We place direct upper limits on the amplitude of gravitational waves from 28 isolated radio pulsars by a coherent multidetector analysis of the data collected during the second science run of the LIGO interferometric detectors. These are the first direct upper limits for 26 of the 28 pulsars. We use coordinated radio observations for the first time to build radio-guided phase templates for the expected gravitational-wave signals. The unprecedented sensitivity of the detectors allows us to set strain upper limits as low as a few times 10^(-24). These strain limits translate into limits on the equatorial ellipticities of the pulsars, which are smaller than 10^(-5) for the four closest pulsars

    Low-energy effects in brane worlds: Liennard-Wiechert potentials and Hydrogen Lamb shift

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    Testing extra dimensions at low-energies may lead to interesting effects. In this work a test point charge is taken to move uniformly in the 3-dimensional subspace of a (3+nn)-brane embedded in a (3+nn+1)-space with nn compact and one warped infinite spatial extra dimensions. We found that the electromagnetic potentials of the point charge match standard Liennard-Wiechert's at large distances but differ from them close to it. These are finite at the position of the charge and produce finite self-energies. We also studied a localized Hydrogen atom and take the deviation from the standard Coulomb potential as a perturbation. This produces a Lamb shift that is compared with known experimental data to set bounds for the parameter of the model. This work provides details and extends results reported in a previous Letter.Comment: Manuscript (LaTeX) and 2 figure files (eps format) used by the manuscript LaTeX fil

    Garlic's ability to prevent in vitro Cu(2+)-induced lipoprotein oxidation in human serum is preserved in heated garlic: effect unrelated to Cu(2+)-chelation

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    BACKGROUND: It has been shown that several extracts and compounds derived from garlic are able to inhibit Cu(2+)-induced low density lipoprotein oxidation. In this work we explored if the ability of aqueous garlic extract to prevent in vitro Cu(2+)-induced lipoprotein oxidation in human serum is affected by heating (a) aqueous garlic extracts or (b) garlic cloves. In the first case, aqueous extract of raw garlic and garlic powder were studied. In the second case, aqueous extract of boiled garlic cloves, microwave-treated garlic cloves, and pickled garlic were studied. It was also studied if the above mentioned preparations were able to chelate Cu(2+). METHODS: Cu(2+)-induced lipoprotein oxidation in human serum was followed by the formation of conjugated dienes at 234 nm and 37°C by 240 min in a phosphate buffer 20 mM, pH 7.4. Blood serum and CuSO(4 )were added to a final concentration of 0.67% and 0.0125 mM, respectively. The lag time and the area under the curve from the oxidation curves were obtained. The Cu(2+)-chelating properties of garlic extracts were assessed using an approach based upon restoring the activity of xanthine oxidase inhibited in the presence of 0.050 mM Cu(2+). The activity of xanthine oxidase was assessed by monitoring the production of superoxide anion at 560 nm and the formation of uric acid at 295 nm. Data were compared by parametric or non-parametric analysis of variance followed by a post hoc test. RESULTS: Extracts from garlic powder and raw garlic inhibited in a dose-dependent way Cu(2+)-induced lipoprotein oxidation. The heating of garlic extracts or garlic cloves was unable to alter significantly the increase in lag time and the decrease in the area under the curve observed with the unheated garlic extracts or raw garlic. In addition, it was found that the garlic extracts were unable to chelate Cu(2+). CONCLUSIONS: (a) the heating of aqueous extracts of raw garlic or garlic powder or the heating of garlic cloves by boiling, microwave or pickling do not affect garlic's ability to inhibit Cu(2+)-induced lipoprotein oxidation in human serum, and (b) this ability is not secondary to Cu(2+)-chelation
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