Gas Dynamics in the Barred Seyfert Galaxy NGC4151 - II. High Resolution HI Study

We present sensitive, high angular resolution (6" x 5") 21-cm observations of the neutral hydrogen in the nearby barred Seyfert galaxy, NGC4151. These HI observations, obtained using the VLA in B-configuration, are the highest resolution to date of this galaxy, and reveal hitherto unprecedented detail in the distribution and kinematics of the HI on sub-kiloparsec scales. A complete analysis and discussion of the HI data are presented and the global properties of the galaxy are related to the bar dynamics presented in Paper I.Comment: 13 pages including 9 figures and 3 tables; accepted for publication in MNRA

Hepatitis C Treatment in High Risk Patients: Implementation of a Successful Community Focused Program

Background: The city of San Francisco boasts a high rate of hepatitis C infection (HCV) among IV drug users indicating the need for a hepatitis C treatment program. It is estimated that over two-thirds of people who are actively infected with HCV are IV drug users (EndHepCSF, 2017), and in 2017 the San Francisco Department of Public Health (SFDPH) estimated that there are 22,500 active people who inject drugs (PWID) in SF (SFDPH, 2017). With the presence of a wide population of IV drug users in SF there is an identified need for intervention to treat this high-risk patient population. Methods: After identification of a significant population of HCV infected patients in a community clinic, the latest evidence for HCV treatment was used to develop and pilot a practical HCV treatment program using glecaprevir/pibrentasvir (Mavyret). The pilot was aimed at testing a protocol in primary care, utilizing evidence based strategies. Results: A total of 6 patients were enrolled in the pilot. There was a successful response rate (100% SVR) among the treatment group, supporting the use of single drug treatment with observed therapy in high risk populations. Conclusion: The results of the project demonstrated that a standardized hepatitis C treatment program is highly efficacious and can be delivered in primary care settings to patients who are high risk

A Radio Study of the Seyfert Galaxy IC 5063: Evidence for Fast Gas Outflow

New radio continuum (8 GHz and 1.4 GHz) and HI 21 cm line observations of the Seyfert 2 galaxy IC 5063 (PKS 2048-572) were obtained with the Australia Telescope Compact Array (ATCA). The 8 GHz image reveals a linear triple structure (~4'', 1.5 kpc) oriented perpendicular to the optical polarization position angle. It is aligned with the inner dust lane and shows strong morphological association with the narrow emission line region (NLR). At 21 cm, very broad (~700 km/s) HI absorption is observed against the strong continuum source. This absorption is almost entirely blueshifted, indicating a fast net outflow, but a faint and narrow redshifted component is also present. In IC 5063 we see clear evidence for strong shocks resulting from the radio plasma-ISM interaction in the central few kpc. However, the energy flux in the radio plasma is an order of magnitude smaller than the energy emitted in emission lines. Thus, shocks are unlikely to account solely for the global ionization of the emission line region, particularly at large distances. The HI emission outlines a warped disk associated with the system of dust lanes some ~2' (~38 kpc) in radius. The lack of kinematically disturbed gas outside the central few kpc, coupled with the disk warp and close morphological connection of the inner dust lanes and the large-scale ionized gas, support the idea that the gas at large radii is photoionized by the central region, while shadowing effects are important in defining its X-shaped morphology. The kinematics of the ionized and of the neutral gas suggests the existence of a dark halo.Comment: 18 pages, 8 Postscript figures, 3 jpeg figures, Postscript preprint is available from http://jhufos.pha.jhu.edu/~zlatan/papers.htm

Parsec-scale radio structures in the nuclei of four Seyfert galaxies

We present 18-cm radio maps of four Seyfert nuclei, Mrk 1, Mrk 3, Mrk 231 and Mrk 463E, made with the European VLBI Network (EVN). Linear radio structures are present in three out of four sources on scales of ~100 pc to ~1 kpc, and the 20-mas beam of the EVN enables us to resolve details within the radio structures on scales of <10 pc. Mrk 3 was also imaged using MERLIN and the data combined with the EVN data to improve the sensitivity to extended emission. We find an unresolved flat-spectrum core in Mrk 3, which we identify with the hidden Seyfert 1 nucleus in this object, and we also see marked differences between the two highly-collimated radio jets emanating from the core. The western jet terminates in a bright hotspot and resembles an FRII radio structure, whilst the eastern jet has more in common with an FRI source. In Mrk 463E, we use the radio and optical structure of the source to argue that the true nucleus lies approximately 1 arcsec south of the position of the radio and optical brightness peaks, which probably represent a hotspot at the working surface of a radio jet. The EVN data also provide new evidence for a 100-pc radio jet powering the radio source in the Type 1 nucleus of Mrk 231. However, the Seyfert 2 galaxy Mrk 1 shows no evidence for radio jets down to the limits of resolution (~10 pc). We discuss the range of radio source size and morphology which can occur in the nuclei of Seyfert galaxies and the implications for Seyfert unification schemes and for radio surveys of large samples of objects.Comment: 23 pages, 7 postscript figures (supplied as separate files), uses AAS aaspp4 LaTeX style file, to appear in the 10 June 1999 issue of The Astrophysical Journa

Jet-cloud interations and the brightening of the narrow line region in Seyfert galaxies

We study the kinematical and brightness evolution of emission line clouds in the narrow line region (NLR) of Seyfert galaxies during the passage of a jet. We derive a critical density above which a cloud remains radiative after compression by the jet cocoon. The critical density depends mainly on the cocoon pressure. Super-critical clouds increase in emission line brightness, while sub-critical clouds generally are highly overheated reducing their luminosity below that of the inter-cloud medium. Due to the pressure stratification in the bow-shock of the jet, a cylindrical structure of nested shells develops around the jet. The most compact and brightest compressed clouds surround the cloud-free channel of the radio jet. To support our analytical model we present a numerical simulation of a supersonic jet propagating into a clumpy NLR. The position-velocity diagram of the simulated H_alpha emission shows total line widths of the order of 500 km/s with large-scale variations in the radial velocities of the clouds due to the stratified pressure in the bow-shock region of the jet. Most of the luminosity is concentrated in a few dense clouds surrounding the jet. These morphological and kinematic signatures are all found in the well observed NLR of NGC1068 and other Seyfert galaxies.Comment: 11 pages, 3 figures, accepted for publication in The Astrophysical Journal Letter

Kinematics of Ionised Gas in the Barred Seyfert Galaxy NGC 4151

We have determined the structure and kinematics of ionised gas in the weak oval bar of the archetypal Seyfert 1 galaxy, NGC 4151, using the TAURUS Fabry-Perot interferometer to simultaneously map the distribution and kinematics of Hbeta emission. We also present broad-band ultraviolet imaging of the host galaxy, obtained with XMM-Newton, that shows the detailed distribution of star formation in the bar and in the optically-faint outer spiral arms. We compare the distribution and kinematics of ionised gas with that previously determined in neutral hydrogen by Mundell & Shone; we suggest that the distribution of bright, patchy UV emission close to the HI shocks is consistent with ionisation by star clusters that have formed in compressed pre-shock gas. These clusters then travel ballistically through the gaseous shock to ionise gas downstream along the leading edge of the bar. In addition, we detect, for the first time, ionised gas within the shock itself which is streaming to smaller radii in the same manner as the neutral gas.Comment: 9 pages, 8 figures. Accepted by MNRA

Heating the bubbly gas of galaxy clusters with weak shocks and sound waves

Using hydrodynamic simulations and a technique to extract the rotational component of the velocity field, we show how bubbles of relativistic gas inflated by AGN jets in galaxy clusters act as a catalyst, transforming the energy carried by sound and shock waves to heat. The energy is stored in a vortex field around the bubbles which can subsequently be dissipated. The efficiency of this process is set mainly by the fraction of the cluster volume filled by (sub-)kpc scale filaments and bubbles of relativistic plasma.Comment: Accepted for publication in ApJ Letters after minor wording changes, 4 figures, 4 page

The association of parental genetic, lifestyle, and social determinants of health with offspring overweight

In the UK, the number of comorbidities seen in children has increased along with the worsening obesity rate. These comorbidities worsen into adulthood. Genomewide association studies have highlighted single nucleotide polymorphisms associated with the weight status of adults and offspring individually. To date, in the UK, parental genetic, lifestyle, and social determinants of health have not been investigated alongside one another as influencers of offspring weight status. A comprehensive obesity prevention scheme would commence prior to conception and involve parental intervention including all known risk factors. This current study aims to identify the proportion of overweight that can be explained by known parental risk factors, including genetic, lifestyle, and social determinants of health with offspring weight status in the UK. Methods: A crosssectional study was carried out on 123 parents. Parental and offspring anthropometric data and parental lifestyle and social determinants of health data were self-reported. Parental genetic data were collected by use of GeneFiX saliva collection vials and genotype were assessed for brain-derived neurotrophic factor (BDNF) gene rs6265, melanocortin 4 receptor (MC4R) gene rs17782313, transmembrane protein 18 (TMEM18) gene rs2867125, and serine/threonine-protein kinase (TNN13K) gene rs1514175. Associations were assessed between parental data and the weight status of offspring. Results: Maternal body mass index modestly predicted child weight status (p < 0.015; R2 = 0.15). More mothers of overweight children carried the MC4R rs17782313 risk allele (77.8%; p = 0.007) compared to mothers of normal-weight children. Additionally, fathers who were not Caucasian and parents who slept for < 7 h/night had a larger percentage of overweight children when compared to their counterparts (p = 0.039; p = 0.014, respectively). Conclusion: Associations exist between the weight status of offspring based solely on parental genetic, lifestyle, and social determinants of health data. Further research is required to appropriately address future interventions based on genetic and lifestyle risk groups on a pre-parent cohort