The integration of tgfu into the secondary school physical education curriculum – how successful has it been?.

In 2005, a new Personal Development, Health and Physical Education (PDHPE) Years 7–10 Syllabus (Board of Studies, 2003) was implemented in NSW (Australia) secondary schools. One area that underwent major changes within the syllabus was that of the teaching of games, with the move towards a TGfU framework. Forty PDHPE teachers were surveyed with questionnaires and focus group interviews to determine their knowledge and understanding of TGfU and the extent to which they have incorporated TGfU into their teaching of games. Pre-service teachers’ observations of Physical Education classes were also used to determine the extent that TGfU was being implemented. Fifty-five percent of PDHPE teachers surveyed had poor knowledge and understanding of TGfU, with 32% unaware that the principles of TGfU were written into the PDHPE syllabus. Forty-five percent of teachers reported that they had incorporated TGfU to some extent into their teaching of games, however only 22% of pre-service teachers surveyed indicated that they had observed classes that incorporated TGfU principles. Continuing teacher training and development is required to support teachers in developing an understanding and skills necessary to utilise a TGfU approach that underpins the teaching of games within the new NSW Years 7-10 PDHPE syllabus

Promoting physical activity through teaching games for understanding in undergraduate teacher education

Physical education teachers play a significant role in influencing the likelihood that their students will engage in lifelong physical activity. However, with declining physical activity levels, particularly amongst young people, and the increased prevalence of obese and overweight children and adolescents, promoting lifelong physical activity is one of the many challenges currently facing physical education teachers. Teachers are required to engage students in quality learning opportunities to develop prescribed learning outcomes and skills, and make the experience enjoyable to enthuse young people to be physically active. This study examines whether teaching games for understanding (TGfU) and technique based pedagogy models in touch football lessons influenced participant physical activity and enjoyment levels

Building community partnerships to enhance participation in sport and physical activity: tertiary institutions and primary schools

Decreasing levels of physical activity and increasing obesity levels amongst Australian children have received much attention in recent years, with research finding that the prevalence of overweight Australian children and adolescents, almost doubled during the ten year period from 1985-1995. Schools have been identified as one community setting that has the potential to address concerns regarding child physical activity and obesity levels by providing an environment which promotes lifelong physical activity, through both structured and unstructured programs

Game sense online - utilising the web for the professional development of physical and health education teachers

In 2005, a new Personal Development, Health and Physical Education (PDHPE) Years 7–10 Syllabus will replace the current syllabus and be implemented with Year 7 and Year 9 students in NSW secondary schools. Informed by contemporary research, the new syllabus represents changes to both the content and the teaching strategies traditionally utilised by teachers. One area that has undergone major changes within the syllabus has been that of the teaching of games, with the move towards a Game Sense framework. It is expected that the implementation of the new syllabus will also be accompanied by a variety of traditional professional development opportunities for teachers. What is also now possible given the affordances of information and communication technologies is online delivery that has the potential to increase teachers’ level of confidence and readiness for implementing a Game Sense approach. This paper discusses the planning and development of a Game Sense online resource within the ActiveHealth framework (www.activehealth.uow.edu.au), a new Physical and Health Education Web resource for teachers. Principles for guiding the development of online teaching resources for practicing and pre-service teachers will also be discussed. The results of a small pilot study designed to investigate teachers perceptions of the effectiveness of such a resource indicate that it is of benefit to teachers in developing a deep understanding of Game Sense, however greater consideration will need to be given to the quality of the learning resources and learning support structures should no face to face opportunities exist

Use and outcomes of targeted therapies in early and metastatic HER2-positive breast cancer in Australia: Protocol detailing observations in a whole of population cohort

Background: The management of human epidermal growth factor receptor 2 (HER2)-positive breast cancer (BC) has changed dramatically with the introduction and widespread use of HER2-targeted therapies. However, there is relatively limited real-world information on patterns of use, effectiveness and safety in whole of population cohorts. The research programme detailed in this protocol will generate evidence on the prescribing patterns, safety monitoring and outcomes of patients with BC treated with HER2- targeted therapies in Australia. Methods/design: Our ongoing research programme will involve a series of retrospective cohort studies that include every patient accessing Commonwealth-funded HER2-targeted therapies for the treatment of early BC and advanced BC in Australia. At the time of writing, our cohorts consist of 11 406 patients with early BC and 5631 with advanced BC who accessed trastuzumab and lapatinib between 2001 and 2014. Pertuzumab and trastuzumab emtansine were publicly funded for metastatic BC in 2015, and future data updates will include patients accessing these medicines. We will use dispensing claims for cancer and other medicines, medical service claims and demographics data for each patient accessing HER2- targeted therapies to undertake this research. Ethics and dissemination: Ethics approval has been granted by the Population Health Service Research Ethics Committee and data access approval has been granted by the Australian Department of Human Services (DHS) External Review Evaluation Committee. Our findings will be reported in peer-reviewed publications, conference presentations and policy forums. By providing detailed information on the use and outcomes associated with HER2-targeted therapies in a national cohort treated in routine clinical care, our research programme will better inform clinicians and patients about the real-world use of these treatments and will assist third-party payers to better understand the use and economic costs of these treatments

Spectral phase effects on nonlinear resonant photochemistry of 1,3-cyclohexadiene in solution

We have investigated the ring opening of 1,3-cyclohexadiene to form 1,3,5-cis-hexatriene (Z-HT) using optical pulse shaping to enhance multiphoton excitation. A closed-loop learning algorithm was used to search for an optimal spectral phase function, with the effectiveness or fitness of each optical pulse assessed using the UV absorption spectrum. The learning algorithm was able to identify pulses that increased the formation of Z-HT by as much as a factor of 2 and to identify pulse shapes that decreased solvent fragmentation while leaving the formation of Z-HT essentially unaffected. The highest yields of Z-HT did not occur for the highest peak intensity laser pulses. Rather, negative quadratic phase was identified as an important control parameter in the formation of Z-HT.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87876/2/114506_1.pd

Development of muon scattering tomography for a detection of reinforcement in concrete

Inspection of ageing, reinforced concrete structures is a world-wide challenge. Existing non-destructive evaluation techniques in civil and structural engineering have limited penetration depth and don't allow to precisely ascertain the configuration of reinforcement within large concrete objects. The big challenge for critical infrastructure (bridges, dams, dry docks, nuclear bioshields etc.) is understanding the internal condition of the concrete and steel, not just the location of the reinforcement. In most new constructions the location should be known and recorded in the as-built drawings, where these might not exist due to poor record keeping for older structures. Muon scattering tomography is a non-destructive and non-invasive technique which shows great promise for high-depth 3D concrete imaging. Previously, we have demonstrated that individual bars with a diameter of 33.7 +- 7.3 mm at 50 cm depth can be located using muon scattering tomography. Here we present an improved method that exploits the periodicity of bar structures. With this new method, reinforcement with bars down to 6 mm thickness can be detected and imaged

Promoting motor skills in low-income, ethnic children: The Physical Activity in Linguistically Diverse Communities (PALDC) nonrandomized trial

This study reports the long-term effects of a professional learning program for classroom teachers on fundamental motor skill (FMS) proficiency of primary school students from ethnically diverse backgrounds. Design: A cluster non-randomized trial using a nested cross-sectional design. Methods: The study was conducted in 8 primary schools located in disadvantaged and culturally diverse areas in Sydney, Australia. The intervention used an action learning framework, with each school developing and implementing an action plan for enhancing the teaching of FMS in their school. School teams comprised 4-5 teachers and were supported by a member of the research team. The primary outcome was total proficiency score for 7 FMS (run, jump, catch, throw, kick, leap, side gallop). Outcome data were analyzed using mixed effects models. Results: Eight-hundred and sixty-two students (82% response rate) were assessed at baseline in 2006 and 830 (82%) at follow-up in 2010. Compared with students in the control schools, there was a significantly greater increase in total motor skill proficiency among children in the intervention schools at follow-up (adjusted difference = 5.2 components, 95%CI [1.65, 8.75]; p. = 0.01) and in four of the seven motor skills. Conclusions: Training classroom teachers to develop and implement units of work based around individual FMS is a promising strategy for increasing FMS among ethnically diverse children over an extended period of time

2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung

<p>Abstract</p> <p>Background</p> <p><it>Pseudomonas aeruginosa </it>infections are associated with progressive life threatening decline of lung function in cystic fibrosis sufferers. Growth of <it>Ps. aeruginosa </it>releases a "grape-like" odour that has been identified as the microbial volatile organic compound 2-aminoacetophenone (2-AA).</p> <p>Methods</p> <p>We investigated 2-AA for its specificity to <it>Ps. aeruginosa </it>and its suitability as a potential breath biomarker of colonisation or infection by Solid Phase Micro Extraction and Gas Chromatography-Mass Spectrometry (GC/MS).</p> <p>Results</p> <p>Cultures of 20 clinical strains of <it>Ps. aeruginosa </it>but not other respiratory pathogens had high concentrations of 2-AA in the head space of <it>in vitro </it>cultures when analysed by GC/MS. 2-AA was stable for 6 hours in deactivated glass sampling bulbs but was not stable in Tedlar^®bags. Optimisation of GC/MS allowed detection levels of 2-AA to low pico mol/mol range in breath. The 2-AA was detected in a significantly higher proportion of subjects colonised with <it>Ps. aeruginosa </it>15/16 (93.7%) than both the healthy controls 5/17 (29%) (p < 0.0002) and CF patients not colonised with <it>Ps. aeruginosa </it>4/13(30.7%) (p < 0.001). The sensitivity and specificity of the 2-AA breath test compared to isolation of <it>Ps. aeruginosa </it>in sputum and/or BALF was 93.8% (95% CI, 67-99) and 69.2% (95% CI, 38-89) respectively. The peak integration values for 2-AA analysis in the breath samples were significantly higher in <it>Ps. aeruginosa </it>colonised subjects (median 242, range 0-1243) than the healthy controls (median 0, range 0-161; p < 0.001) and CF subjects not colonised with <it>Ps. aeruginosa </it>(median 0, range 0-287; p < 0.003)</p> <p>Conclusions</p> <p>Our results report 2-AA as a promising breath biomarker for the detection of <it>Ps. aeruginosa </it>infections in the cystic fibrosis lung.</p

End stage renal disease and survival in people with diabetes:a national database linkage study

© The Author 2014. Published by Oxford University Press on behalf of the Association of Physicians. Funding This work was supported by the Wellcome Trust through the Scottish Health Informatics Programme (SHIP). The SHIP is collaboration between the Universities of Aberdeen, Dundee, Edinburgh, Glasgow and St Andrews and the Information Services Division of National Health Service National Service Scotland. Funding for diabetes register linkage and data extraction was provided by the Chief Scientist’s Office of the Scottish Government. The Scottish Diabetes Research Network receives financial support from National Health Services Research Scotland. The Scottish Renal Registry is funded by the Information Services Division of National Health Service National Services Scotland but relies heavily on the goodwill of the contributing renal units who spent a large amount time working with Scottish Renal Registry staff to ensure that the data held within the register are accurate and complete.Peer reviewedPublisher PD