Mitochondrial Dynamics at the Interface of Immune Cell Metabolism and Function

Immune cell differentiation and function are crucially dependent on specific metabolic programs dictated by mitochondria, including the generation of ATP from the oxidation of nutrients and supplying precursors for the synthesis of macromolecules and post-translational modifications. The many processes that occur in mitochondria are intimately linked to their morphology that is shaped by opposing fusion and fission events. Exciting evidence is now emerging that demonstrates reciprocal crosstalk between mitochondrial dynamics and metabolism. Metabolic cues can control the mitochondrial fission and fusion machinery to acquire specific morphologies that shape their activity. We review the dynamic properties of mitochondria and discuss how these organelles interlace with immune cell metabolism and function

Range safety signal attenuation by the Space Shuttle main engine exhaust plumes

An analysis of attenuation of the range safety signal at 416.5 MHz observed after SRB separation and ending at hand over to Bermuda, during which transmission must pass through the LOX/H2 propelled main engine exhaust plumes, is summarized. Absorption by free electrons in the exhaust plume can account for the nearly constant magnitude of the observed attenuation during this period; it does not explain the short term transient increases that occur at one or more times during this portion of the flight. It is necessary to assume that a trace amount (about 0.5 ppm) of easily ionizable impurity must be present in the exhaust flow. Other mechanisms of attenuation, such as scattering by turbulent fluctuations of both free and bound electrons and absorption by water vapor, were examined but found to be inadequate to explain the observations

Specific training, unions, and the relationship between employer size and wages

In this paper I demonstrate that the explanatory power of employer size variables in nonunion wage regressions is diminished by allowing the coefficient of tenure (years on current job) to vary with employer size. Among nonunion workers, average tenure and the coefficient of tenure increase with both firm size and plant size. This pattern is consistent with the hypothesis that investment in specific human capita1 accounts for much of the previously unexplained relationship between employer size and nonunion wages . The relationships between compensation tenure, and employer size are different for union workers. Employer size is less important generally, and the importance of plant size is especially low. Also, the data are more consistent with the specific human capital model when union compensation is measured by annual income rather than the hourly wage.

Connecting Mathematics and the Applied Science of Energy Conservation

To effectively teach science in the elementary classroom, pre-service K-8 teachers need a basic understanding of the underlying concepts of physics, which demand a strong foundation in mathematics. Unfortunately, the depth of mathematics understanding of prospective elementary teachers has been a growing and serious concern for several decades. To overcome this challenge, a two-pronged attack was used in this study. First. students in mathematics courses were coupled with physical science courses by linking registration to ensure co-requisites were taken. This alone improved passing rates. Secondly, an energy conservation project was introduced in both classes that intimately tied the theoretical mathematics base knowledge to problems in physical science, energy efficiency, and household economics. These connections made the mathematics highly relevant to the students and improved both their theoretical understanding and their grades. Together, the two approaches of tying mathematics to physical science and applying mathematical skills to solving energy efficiency problems have shown to be extremely effective at improving student performance. This five-year study not only exhibited record improvements in student performance, but also can be easily replicated at other institutions experiencing similar challenges in training pre-service elementary school teachers

Solutions of the boundary Yang-Baxter equation for ADE models

We present the general diagonal and, in some cases, non-diagonal solutions of the boundary Yang-Baxter equation for a number of related interaction-round-a-face models, including the standard and dilute A_L, D_L and E_{6,7,8} models.Comment: 32 pages. Sections 7.2 and 9.2 revise

Characterization-curing-property studies of HBRF 55A resin formulations

Characterization curing property investigations on HBRF 55A resin formulations are reported. The initial studies on as received cured samples cut from a full-size FWC are reviewed. Inadequacies of as-received and aged samples are pointed out and additional electron microscopic evidence is offered. Characterization of as-received ingredients of HBRF 55A formulation is described. Specifically, Epon 826, Epon 828, EpiRez 5022, RD-2 and various amines, including Tonox and Tonox 60.40, were characterized. Cure kinetics of various formulations are investigated. Changes in physical/thermal properties (viscosity, specific heat, thermal conductivity and density) during cure are described

The stability of new transparent polymeric materials: The epoxy trimethoxyboroxine system. Part 1: The preparation, characterization and curing of epoxy resins and their copolymers

The effects of resin composition, curing conditions fillers, and flame retardant additives on the flammability of diglycidyl ether of bisphenol-A (DGEBA) as measured by the oxygen index is examined. The oxygen index of DGEBA cured with various curing agents was between 0.198 to 0.238. Fillers and flame retardant additives can increase the oxygen index dependent on the material and the amount used. Changes in the basic cured resin properties can be anticipated with the addition of noncompatible additives. High flame resistant epoxy resins with good stability and mechanical properties are investigated