Correlating matched-filter model for analysis and optimisation of neural networks

A new formalism is described for modelling neural networks by means of which a clear physical understanding of the network behaviour can be gained. In essence, the neural net is represented by an equivalent network of matched filters which is then analysed by standard correlation techniques. The procedure is demonstrated on the synchronous Little-Hopfield network. It is shown how the ability of this network to discriminate between stored binary, bipolar codes is optimised if the stored codes are chosen to be orthogonal. However, such a choice will not often be possible and so a new neural network architecture is proposed which enables the same discrimination to be obtained for arbitrary stored codes. The most efficient convergence of the synchronous Little-Hopfield net is obtained when the neurons are connected to themselves with a weight equal to the number of stored codes. The processing gain is presented for this case. The paper goes on to show how this modelling technique can be extended to analyse the behaviour of both hard and soft neural threshold responses and a novel time-dependent threshold response is described

Role of Dendritic Cell Maturity/Costimulation for Generation, Homeostasis, and Suppressive Activity of Regulatory T Cells

Tolerogenicity of dendritic cells (DCs) has initially been attributed exclusively to immature/resting stages, while mature/activated DCs were considered strictly immunogenic. Later, all different subsets among the myeloid/conventional DCs and plasmacytoid DCs have been shown to bear tolerogenic potential, so that tolerogenicity could not be attributed to a specific subset. Immunosuppressive treatments of immature DC subsets could prevent re-programming into mature DCs or upregulated inhibitory surface markers or cytokines. Furthermore, the different T cell tolerance mechanisms anergy, deletion, immune deviation, and suppression require different quantities and qualities of costimulation by DCs. Since expansion of regulatory T cells (Tregs) has been shown to be promoted best by fully mature DCs the role of CD80/B7-1 and CD86/B7-2 as major costimulatory molecules for Treg biology is under debate. In this review, we discuss the role of these and other costimulatory molecules on myeloid DCs and their ligands CD28 and CD152/CTLA-4 on Tregs for peripheral conversion from naive CD4+ T cells into the major subsets of Foxp3+ Tregs and Foxp3− IL-10+ regulatory type-1 T cells (Tr1) or Tr1-like cells and their role for peripheral maintenance in the steady state and after activation

Vegetation Patterns in and among Pannes (Calcareous Intradunal Ponds) at the Indiana Dunes National Lakeshore, Indiana

The relationships between plant species composition and dispersion, water chemistry and water depth/depth to water table were studied in five calcareous intradunal ponds (pannes) bordering the southern tip of Lake Michigan. The panne systems contained eight plant species threatened and endangered in Indiana. The aquatic zone was dominated by Chara, the pond edge by Rhynchospora capillacea, Juncus balticus and Utricularia cornuta, and the area surrounding the pond by Hypericum kalmianum. The water chemistry was typical of hardwater ponds in the area, probably affecting species composition but not species dispersion within the pannes. A significant correlation between the first axis scores from a reciprocal-averaging ordination and water depth/depth to water was demonstrated. Panne species are fitted to a model based on hydrology proposed by van der Laan for dune-slack vegetation in the Netherlands

Collisional properties of cold spin-polarized nitrogen gas: theory, experiment, and prospects as a sympathetic coolant for trapped atoms and molecules

We report a combined experimental and theoretical study of collision-induced dipolar relaxation in a cold spin-polarized gas of atomic nitrogen (N). We use buffer gas cooling to create trapped samples of 14N and 15N atoms with densities 5+/-2 x 10^{12} cm-3 and measure their magnetic relaxation rates at milli-Kelvin temperatures. Rigorous quantum scattering calculations based on accurate ab initio interaction potentials for the 7Sigma_u electronic state of N2 demonstrate that dipolar relaxation in N + N collisions occurs at a slow rate of ~10^{-13} cm3/s over a wide range of temperatures (1 mK to 1 K) and magnetic fields (10 mT to 2 T). The calculated dipolar relaxation rates are insensitive to small variations of the interaction potential and to the magnitude of the spin-exchange interaction, enabling the accurate calibration of the measured N atom density. We find consistency between the calculated and experimentally determined rates. Our results suggest that N atoms are promising candidates for future experiments on sympathetic cooling of molecules.Comment: 48 pages, 17 figures, 3 table

Efficient dynamic modeling of reflective semiconductor optical amplifier

“Copyright © [2013] IEEE. Reprinted from IEEE Journal of Selected Topics in Quantum Electronics. ISSN: 1932-4553. This material is posted here with permission of the IEEE. Internal or personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to [email protected]. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.”RSOA is considered a strong candidate to play an important role in realizing the next generation WDM PON, based on the wavelength reuse concept. Therefore, accurate and efficient modeling of RSOA is of significant importance. We present a time-domain wideband model for simulation of spatial and temporal distribution of photons and carriers in a bulk RSOA. A trade-off between the accuracy and the computational efficiency of the model is studied. Multi-objective genetic algorithm is utilized for parameter extraction. Experimental validation has been performed for continuous wave input, NRZ and QPSK signaling pulses up to 40 Gb/s of bit rate, in both amplification and remodulation regimes. Saturation, noise, chirp and signal broadening are successfully predicted, while reducing the computational time compared to other wideband models

Antioxidant Capacities and Phenolic Levels of Different Varieties of Serbian White Wines

The biologically active compounds in wine, especially phenolics, are responsible for reduced risk of developing chronic diseases (cardiovascular disrease, cancer, diabetes, etc.), due to their antioxidant activities. We determined the contents of total phenolics (TP) and total flavonoids (TF) in selected Serbian white wines by colorimetric methods. Total antioxidant activity (TAA) of the white wines was analyzed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging capacity assay. Međaš beli had the highest content of TP, TF and TAA. The radical scavenging capacity (RSC) and total antioxidant activity (TAA) of white wines were 15.30% and 1.055 mM Trolox equivalent, respectively. Total phenolic (TP) and total flavonoid (TF) contents in white wines ranged from 238.3 to 420.6 mg gallic acid equivalent per L of wines and 42.64 to 81.32 mg catechin equivalent per L of wines, respectively. A high and significant correlation between antioxidant activity and total phenolic content was determined in wines (R2 = 0.968, p < 0.01). For the individual polyphenols determination we used a high performance liquid chromatography (HPLC)-diode array detection (DAD) technique. The majority of white wine polyphenols was represent by four hydroxycinnamic acids (HCAs)

Ratio of maximum hamstring torque to maximum quadriceps torque in professional basketball and soccer players

Purpose: The aim of the study was to determine the differences between football players and basketball players in the mean absolute values of maximum torque flexors and extensors, ratio of maximum hamstring torque to maximum quadriceps torque dominant (DOM) non-dominant (ND) leg and differences in bilateral imbalance of flexor muscles and knee extensors. Material and methods: The research included a sample of 39 professional athletes. The first subsample included 19 professional basketball players while the second subsample included 20 professional soccer players. Results: Based on the results of the torques of the extensors in the knee joint of the DOM and ND legs, it was established that there is no statistically significant difference between basketball players and football players. However, a statistically significant difference was found in the torque flexors of the knee joint DOM (p≤0.01) and ND (p≤0.00) of the leg between basketball players and football players. On the other hand, the results of the research indicate that the difference between basketball players and football players in the ratio of Hamstrings peak torque to Quadriceps peak torque was recorded only in the ND leg (p≤0.02), while the difference in the DOM leg is not statistically significant. The results of our study indicate that basketball players have a higher percentage of imbalances compared to football players, especially in m. hamstrings. Conclusion: This study provides normative data on populations specific to soccer and basketball, but does not provide evidence of the ability of the isokinetic assessment of lower extremity muscle strength to predict injuries to football players and basketball players