Innovative methods of atomic force microscopy in oncology diagnostics

The purpose of this work is to study the morphological forms of erythrocytes, and also pathomorphological changes in prostate gland and kidneys with the use of atomic force microscopy (AFM) during oncological processes. Results: The decrease of discocytes was observed, and the number of transitional, pre-hemolytic and degenerative forms of erythrocytes increased. During the study of the external level of erythrocytes using AFM, it was established that the depth of the discocyte cavity counted by the study of a cell profile changed significantl

Index insurance as a tool to improve the Russian system of insuring risks of agricultural organizations with state support

The Russian system of insuring risks of agricultural organizations requires a qualitative restructuring based on the increased responsibility of insurers and state participation. Low rates of developing the system of insuring risks of agricultural organizations with state support require seeking for new forms of insurance in the current conditions. The article points out that the use of the index insurance is currently one of the priority directions for the development of the country's agribusiness in general. An algorithm for creating an index insurance service is presented, the purpose of which is to substantiate the possibility of applying index insurance under the conditions of risky farming. A comparative analysis of the economic efficiency of index insurance of the regional grain crops and insurance of grain crops with state support was conducted. It was concluded that the use of index insurance could be useful for other regions that were identical to Kalmykia in terms of natural and climatic environment. The theoretical results obtained by the author can be considered as one of the priority directions for the development of the theoretical and methodological toolkit for insuring risks of agricultural organizations, can become a theoretical and empirical factual foundation for the formation of scientific grounds for regional economic policy in relation to agricultural organizations based on coordinating the interests of the triad of participants: state authorities, agricultural organizations, insurance organizations, as well as program forecasting and project developments.peer-reviewe

Realization of youth housing policy (on the example of the city district the Dry Ravine of Sverdlovsk region)

The Article discusses the program of the municipal youth housing policy. Analyzes the content of the program activities and criteria the results of the program. The article contains the results of the study of youth to assess the effectiveness of youth housing policy in the city district Sukhoi Log.Рассматривается программа муниципальной молодежной жилищной политики. Анализируется содержание мероприятий программы и критерии оценки результатов реализации программы. Приводятся данные опроса молодежи по оценке эффективности молодежной жилищной политики в городском округе Сухой Лог

Features of micro- and ultrastructure of low-fat butter and its low-fat analogues

The aim of the research was to study the features of the structure of low-fat butter and butter pastes, which, in terms of composition and properties, more fully meet the requirements of a healthy diet than high-fat types of butter. The objects of research were: butter with fat content of 72.5%; butter with fat content of 55% made with the addition of skimmed milk powder; butter of the same fat content with the addition of stabilizers based on guar and xanthan gums and emulsifiers based on monoand diglycerides of fatty acids; butter pastes with fat content of 45% with similar additives used to increase the stability of the process of butter formation and improve the texture. The microstructure was studied using an MBI-6 microscope, and the ultramicrostructure was studied using a Phillips electron microscope. In the first case, the sample was prepared by crushing the sample, in the second one — by the method of ultrafast freeze-fracture and etching. Researches have shown that the use of the introduced ingredients improves the homogeneity of the structure of the studied products. Due to the ability of milk proteins and stabilizers to retain moisture, it is more evenly distributed and well retained in the fat matrix of the product, formed from crystalline and liquid fat in the form of a continuous phase, which is confirmed by a sufficient penetration depth of the fat-soluble dye. Plasma droplets in butter with fat content of 72.5% and 55% are more isolated than in butter pastes, as indicated by the greater penetration depth of the water-soluble dye. The average diameter of isolated moisture droplets in low-fat products was 3.3–5.4 μm, and the average diameter of the fat globules that form the basis of the crystalline framework was 5.4–7.4 μm, depending on the composition of the product. For butter with fat content of 72.5%, the values of these indicators were 2.8 and 4.0 μm. The results of the study indicate the presence of differences in the sizes of structural elements, but at the same time confirm the uniformity of the structure of low-fat products, allowing them to be attributed to dispersions «water-in-oil»

The course and perinatal outcomes of rapid delivery in women

This paper presents the clinical characteristics of pregnancy course and the features of uterine con-tractions during rapid delivery. The character of perinatal complications of rapid delivery has been studied. The morphological characteristics of the cervix in women with shortened delivery period have been presented. It was revealed that the vast majority of rapid delivery is not accompanied by excessively strong labor. Adverse perinatal outcomes for both a mother and a newborn are caused not by the nature of labor, but by infectious-inflammatory processes, on which background an actual pregnancy had occurred and developed, which has been evidenced by both clinical observations and the results of histological examination of cervix tissue of rap-idly delivering women

New aspects in the study of clinical and morphological features of uterine blood flow in type 1 diabetes mellitus in the mother

The aim of the study was to develop new approaches to the study of modern aspects of the clinical and morphological features of uterine blood flow in type I diabetes mellitus in the mothe