Achados de RM cerebral na doença de Lhermitte-Duclos

Universidade Federal de São Paulo (UNIFESP) Departamento de Neurologia Divisão de Neurologia GeralUNIFESP, Depto. de Neurologia Divisão de Neurologia GeralSciEL

Sinal da língua brilhante: um marcador diagnóstico para esclerose lateral amiotrófica

Universidade Federal de São Paulo (UNIFESP) Departamento de Neurologia Unidade NeuromuscularUNIFESP, Depto. de Neurologia Unidade NeuromuscularSciEL

Invaginação basilar em cefaleia associada ao esforço físico e torcicolo recorrente

Universidade Federal de São Paulo (UNIFESP)Universidade Federal de São Paulo (UNIFESP) Departamento de Neurologia e NeurocirurgiaUNIFESP, Depto. de Neurologia e NeurocirurgiaSciEL

Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies

During recent years, an increasing number of neuromuscular diseases have been recognized either to be caused primarily by autoimmune mechanisms, or to have important autoimmune components. the involved pathophysiological mechanisms and clinical manifestations have been better recognized and many of these disorders are potentially treatable by immunosuppression or by immunomodulation with intravenous immunoglobulin (IVIg). IVIg has been tried in a variety of immune-mediated neurological diseases, being target of widespread use in central and peripheral nervous systems diseases. Objective: To give an overview of the main topics regarding the mechanism of action and different therapeutic uses of IVIg in neurological practice, mainly in neuromuscular diseases.Universidade Federal de São Paulo, Dept Neurol & Neurocirurgia, Div Doencas Neuromusculares, BR-04023900 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Neurol & Neurocirurgia, Div Doencas Neuromusculares, BR-04023900 São Paulo, BrazilWeb of Scienc

C9orf72-related disorders: expanding the clinical and genetic spectrum of neurodegenerative diseases

Neurodegenerative diseases represent a heterogeneous group of neurological conditions primarily involving dementia, motor neuron disease and movement disorders. They are mostly related to different pathophysiological processes, notably in family forms in which the clinical and genetic heterogeneity are lush. in the last decade, much knowledge has been acumulated about the genetics of neurodegenerative diseases, making it essential in cases of motor neuron disease and frontotemporal dementia the repeat expansions of C9orf72 gene. This review analyzes the main clinical, radiological and genetic aspects of the phenotypes related to the hexanucleotide repeat expansions (GGGGCC) of C9orf72 gene. Future studies will aim to further characterize the neuropsychological, imaging and pathological aspects of the extra-motor features of motor neuron disease, and will help to provide a new classification system that is both clinically and biologically relevant.Universidade Federal de São Paulo, Dept Neurol & Neurocirurgia, Div Doencas Neuromusculares, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Neurol & Neurocirurgia, Div Doencas Neuromusculares, São Paulo, BrazilWeb of Scienc

Lumbago and alopecia in a patient with leukodystrophy: think on CARASIL

Univ Fed Sao Paulo, Div Doencas Neuromusculares, Dept Neurol & Neurocirugia, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Div Doencas Neuromusculares, Dept Neurol & Neurocirugia, Sao Paulo, SP, BrazilWeb of Scienc

Burning pain attacks and red skin in a young women

Univ Fed Sao Paulo, Div Doencas Neuromusculares, Dept Neurol & Neurocirurgia, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Div Doencas Neuromusculares, Dept Neurol & Neurocirurgia, Sao Paulo, SP, BrazilWeb of Scienc

Rapidly progressive subacute motor neuronopathy disclosing type B2 thymoma

Univ Fed Sao Paulo, Dept Neurol & Neurocirurgia, Div Doencas Neuromusculares, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Neurol & Neurocirurgia, Div Doencas Neuromusculares, Sao Paulo, SP, BrazilWeb of Scienc

Paracoccidioidomicose: uma causa rara de encefalomielopatia infecciosa

Universidade Federal de São Paulo (UNIFESP)Universidade Federal de São Paulo (UNIFESP) Departamento de Neurologia e NeurocirurgiaUNIFESP, Depto. de Neurologia e NeurocirurgiaSciEL