3 research outputs found

    Growth and body composition in children with type 1 diabetes mellitus

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    OBJECTIVE: To evaluate the growth and body composition of pre-pubertal diabetic children, and to check for influence of the age of diabetes onset and length, sex, insulin requirement and glycosylated hemoglobin. PATIENTS AND METHODS: 59 diabetic children (39 M; 29 F), age 1.2-11.5 years, and 67 controls (36 M; 31 F), age 1.2-11.7 years were included. Weight, height, body mass index (BMI), arm circumference, skin folds, fat mass and muscle areas were evaluated and transformed into standard deviation scores (SDS). RESULTS: Among the diabetic children the mean height SDS was -0.13 (&plusmn; 0.97) while in the control group it was 0.28 (&plusmn; 0.86) (p= 0.013). The difference between the first and the current height SDS showed that the height SDS decreased significantly (p< 0.001) and multiple regression analysis indicated correlation with the duration of the disease. The mean arm fat SDS also revealed difference (p< 0.001). The means for weight, BMI, addition of 3 skinfolds and muscle mass did not demonstrate difference between the groups. CONCLUSIONS: The diabetic children showed reduction of height SDS during the period studied and they were significantly shorter than the controls, even though their statures were within the population standards. The arm fat area also showed to be increased in relation with the controls.OBJETIVOS: Avaliar o crescimento e a composição corporal de diabĂ©ticos tipo 1, prĂ©-pĂșberes, em relação Ă  idade de inĂ­cio e tempo da doença, sexo, dose de insulina e hemoglobina glicada mĂ©dia. PACIENTES E MÉTODOS: Foram incluĂ­das no estudo 59 crianças diabĂ©ticas (30 M; 29 F), entre 1,2 e 11,5 anos, e 67 controles (36 M; 31 F), entre 1,2 e 11,7 anos. Peso, altura, IMC, perĂ­metro braquial, pregas cutĂąneas e ĂĄreas de massa gorda e muscular braquial foram avaliados e transformados em escore z. RESULTADOS: Verificou-se que entre os diabĂ©ticos a mĂ©dia de escore z de altura foi -0,13 (&plusmn; 0,97), enquanto no grupo controle foi de 0,28 (&plusmn; 0,86) (p= 0,013). A diferença entre os escores de altura inicial e atual mostrou perda estatural (p< 0,001) e a anĂĄlise multivariada demonstrou associação com tempo de doença. TambĂ©m observou-se diferença na ĂĄrea de gordura braquial (p< 0,001). As mĂ©dias de escore z de peso, IMC, soma de 3 dobras e ĂĄrea muscular braquial nĂŁo diferiram entre os grupos. CONCLUSÕES: As crianças diabĂ©ticas apresentaram perda de estatura durante o perĂ­odo de acompanhamento e eram significativamente mais baixas que os controles, embora suas alturas ainda estivessem dentro dos padrĂ”es de normalidade. TambĂ©m mostraram ĂĄrea de gordura braquial aumentada em relação aos controles.49049
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