A Model for Semantic IS Standards

We argue that, in order to suggest improvements of any kind to semantic information system (IS) standards, better understanding of the conceptual structure of semantic IS standard is required. This study develops a model for semantic IS standard, based on literature and expert knowledge. The model is validated by case descriptions of two particular semantic IS standards. The model shows characteristics of semantic IS standards. Some of these characteristics might become steering factors for improving the development, adoption and quality of standards, among others

From the Frontier: Translating Research to Practice…QI as the Hinge Point

This article is number three in the series From the Frontier: Translating Research to Practice. The narrative describes the work of a practice-academic network in Minnesota which explored the degree to which having a culture of quality at the local health department level influenced the capacity to implement a new statewide initiative. The network conducted a mixed-methods study of grantees funded to develop and implement local policy, systems, and environmental change strategies to promote nutrition, increase activity, and reduce tobacco use and exposure. The results of their study indicated that grantees with higher performance levels in Quality Improvement (QI) were much more likely to exceed expectations in local initiatives compared to grantees with lower levels of “QI maturity”. The study results are being used at the local level to advocate for authority to bolster QI and at the state level to establish baseline capacity of new grantees in order to customize technical assistance. This provides further evidence that systems-level research is possible in such practice-academic networks, and that findings from such research are immediately translatable

Editorial Comment: Differences in Definitions of EBPH and Evidence: Implications for Communication with Practitioners

Through interviews of 12 members of an expert panel – importantly, involving both practitioners and researchers/academicians – Aronson and colleagues sought to understand how evidence-based public health (EBPH) is defined, what counts as “evidence”, and what EBPH actually looks like when operationalized in a local health department. What Aronson and colleagues have shown us is how critical it is that in both creating and implementing EBPH, especially in practice-based research, practitioner and researcher/academician develop a shared understanding of EBPH before the dance begins, especially for practice-based research

From the Frontier: Translating Research to Practice...a Story of Economic Survival

This article is number two in the series From the Frontier: Translating Research to Practice. The narrative describes the interactions between a local health department director and two academicians in addressing the impact of the 2008 financial crisis. In a first set of activities, practice-academic partners used Financial and Operational Ratio and Trend Analysis to identify periods of a negative total margin and the impact of that on the agency’s declining fund balance. The use of private sector processes of retrenchment, repositioning, and reorganization led to a financial turnaround for the agency. In a second set of activities, practice-academic partners analyzed consolidation of multiple local health departments as one option for improving long-term financial stability. These connected activities provide examples of both implementation science and practice-based research

From the Frontier: Translating Research to Practice

The purpose of this invited article is to describe the process of translating research into public health practice. An example is provided, showing how questions arose in the practice setting, a researcher was identified to help answer the questions, and findings from the research were applied in the practice setting. In this example, Dr. Lea LaFave (Community Health Institute/JSI in New Hampshire) worked with Dr. Danielle Varda (Assistant Professor at the University of Colorado/ Denver, School of Public Affairs) to use social network analysis to better understand a network of coalitions focused on underage substance abuse. The social network analysis revealed that networks varied significantly in the number and depth of collaborations (from none to fully integrated) within each network. The larger implications of these findings suggest that the way people conceptualize complex systems varies tremendously, and that this has fundamental importance for understanding how to improve such systems

The Measurement of Quality of Semantic Standards: the Application of a Quality Model on the SETU standard for eGovernment

eGovernment interoperability should be dealt with using high-quality standards. A quality model for standards is presented based on knowledge from the software engineering domain. In the tradition of action research the model is used on the SETU standard, a standard that is mandatory in the public sector of the Netherlands in order to achieve eGovernment interoperability. This results in improvement suggestions for the SETU standards, just as improvement suggestions for the quality model have been identified. Most importantly it shows that a quality model can be used for several purposes, including selecting standards for eGovernment interoperability

Metabolic stability of the fucose in rat transferrin

AbstractThe metabolic behaviour of the chitobiose core fucose that is a natural constituent of a large proportion of rat transferrin molecules was studied in rats comparatively to that of the polypeptide portion of the glyco-protein by using appropriate labels ([3H]fucose and 125I) and affinity chromatographic techniques (lentil-Sepharose). No evidence was obtained to suggest that this residue is cleaved from the glycan in significant amounts before removal of the entire glycoprotein for catabolism. Similarly, [14C]fucose linked to GlcNAc residues in the antennae of human asialotransferrin was being eliminated in pigeons at the same rate as the polypeptide itself. It is concluded that in spite of transferrin's exposure to the cellular milieu, the fate of its fucose is distinctly different from that of the same in plasma membrane glycoproteins