Augmenting Live Performance Dance through Mobile Technology

We present a pilot study investigating the use of mobile technology to augment live performance dance. An augmented performance was created and viewed through an tablet device then analysed from a technical and audience standpoint. Low complexity augmentations were found to be very effective, however the device placed restrictions on higher complexity augmentations, the performance length and the stage/audience spatial arrangements. A low-number audience test indicated that augmentation of live performance was a credible concept, though there are some clear challenges to be overcome specifically around speed of technology and weight of device

Recurrent ~24 h Periods in RXTE ASM Data

Analysis of data from the Rossi X-ray Timing Explorer satellite's All Sky Monitor instrument for several X-ray binary sources has identified a recurrent \~24 h period. This period is sometimes highly significant, giving rise to the possibility of it being identified as an orbital or super-orbital period. Further analysis has revealed the same period in a number of other X-ray sources. As a result this period has been discounted as spurious, described variously as arising from daily variations in background levels and beating between the sampling period and long-term secular trends in the light curves. We present here an analysis of the spurious periods and show that the dominant mechanism is in fact spectral leakage of low-frequency power present in the light curves.Comment: 9 Pages, 10 figures, 1 table, submitted to PASA 20th December 2004. Added 1 page of text and 3 figures to clarify results and discussion. Resubmitted 16th May 2005. Accepted 25th June 200

Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP.

Platelet activation in response to stimulation of the Protease Activated Receptor 4 (PAR4) receptor differs by race. One factor that contributes to this difference is the expression level of Phosphatidylcholine Transfer Protein (PCTP), a regulator of platelet PAR4 function. We have conducted an expression Quantitative Trait Locus (eQTL) analysis that identifies single nucleotide polymorphisms (SNPs) linked to the expression level of platelet genes. This analysis revealed 26 SNPs associated with the expression level of PCTP at genome-wide significance (p \u3c 5×10(-8)). Using annotation from ENCODE and other public data we prioritised one of these SNPs, rs2912553, for functional testing. The allelic frequency of rs2912553 is racially-dimorphic, in concordance with the racially differential expression of PCTP. Reporter gene assays confirmed that the single nucleotide change caused by rs2912553 altered the transcriptional potency of the surrounding genomic locus. Electromobility shift assays, luciferase assays, and overexpression studies indicated a role for the megakaryocytic transcription factor GATA1. In summary, we have integrated multi-omic data to identify and functionalise an eQTL. This, along with the previously described relationship between PCTP and PAR4 function, allows us to characterise a genotype-phenotype relationship through the mechanism of gene expression

Structural basis of mitochondrial receptor binding and constriction by DRP1.

Mitochondrial inheritance, genome maintenance and metabolic adaptation depend on organelle fission by dynamin-related protein 1 (DRP1) and its mitochondrial receptors. DRP1 receptors include the paralogues mitochondrial dynamics proteins of 49 and 51 kDa (MID49 and MID51) and mitochondrial fission factor (MFF); however, the mechanisms by which these proteins recruit and regulate DRP1 are unknown. Here we present a cryo-electron microscopy structure of full-length human DRP1 co-assembled with MID49 and an analysis of structure- and disease-based mutations. We report that GTP induces a marked elongation and rotation of the GTPase domain, bundle-signalling element and connecting hinge loops of DRP1. In this conformation, a network of multivalent interactions promotes the polymerization of a linear DRP1 filament with MID49 or MID51. After co-assembly, GTP hydrolysis and exchange lead to MID receptor dissociation, filament shortening and curling of DRP1 oligomers into constricted and closed rings. Together, these views of full-length, receptor- and nucleotide-bound conformations reveal how DRP1 performs mechanical work through nucleotide-driven allostery

An In Depth Study into Using EMI Signatures for Appliance Identification

Energy conservation is a key factor towards long term energy sustainability. Real-time end user energy feedback, using disaggregated electric load composition, can play a pivotal role in motivating consumers towards energy conservation. Recent works have explored using high frequency conducted electromagnetic interference (EMI) on power lines as a single point sensing parameter for monitoring common home appliances. However, key questions regarding the reliability and feasibility of using EMI signatures for non-intrusive load monitoring over multiple appliances across different sensing paradigms remain unanswered. This work presents some of the key challenges towards using EMI as a unique and time invariant feature for load disaggregation. In-depth empirical evaluations of a large number of appliances in different sensing configurations are carried out, in both laboratory and real world settings. Insights into the effects of external parameters such as line impedance, background noise and appliance coupling on the EMI behavior of an appliance are realized through simulations and measurements. A generic approach for simulating the EMI behavior of an appliance that can then be used to do a detailed analysis of real world phenomenology is presented. The simulation approach is validated with EMI data from a router. Our EMI dataset - High Frequency EMI Dataset (HFED) is also released

Low-threshold organic laser based on an oligofluorene truxene with low optical losses

A blue-emitting distributed feedback laser based on a star-shaped oligofluorene truxene molecule is presented. The gain, loss, refractive index, and (lack of) anisotropy are measured by amplified spontaneous emission and variable-angle ellipsometry. The waveguide losses are very low for an organic semiconductor gain medium, particularly for a neat film. The results suggest that truxenes are promising for reducing loss, a key parameter in the operation of organic semiconductor lasers. Distributed feedback lasers fabricated from solution by spin-coating show a low lasing threshold of 270 W/cm(2) and broad tunability across 25 nm in the blue part of the spectrum

The Impact of Halo Properties, Energy Feedback and Projection Effects on the Mass-SZ Flux Relation

We present a detailed analysis of the intrinsic scatter in the integrated SZ effect - cluster mass (Y-M) relation, using semi-analytic and simulated cluster samples. Specifically, we investigate the impact on the Y-M relation of energy feedback, variations in the host halo concentration and substructure populations, and projection effects due to unresolved clusters along the line of sight (the SZ background). Furthermore, we investigate at what radius (or overdensity) one should measure the integrated SZE and define cluster mass so as to achieve the tightest possible scaling. We find that the measure of Y with the least scatter is always obtained within a smaller radius than that at which the mass is defined; e.g. for M_{200} (M_{500}) the scatter is least for Y_{500} (Y_{1100}). The inclusion of energy feedback in the gas model significantly increases the intrinsic scatter in the Y-M relation due to larger variations in the gas mass fraction compared to models without feedback. We also find that variations in halo concentration for clusters of a given mass may partly explain why the integrated SZE provides a better mass proxy than the central decrement. Substructure is found to account for approximately 20% of the observed scatter in the Y-M relation. Above M_{200} = 2x10^{14} h^{-1} msun, the SZ background does not significantly effect cluster mass measurements; below this mass, variations in the background signal reduce the optimal angular radius within which one should measure Y to achieve the tightest scaling with M_{200}.Comment: 12 pages, 6 figures, to be submitted to Ap

Systematic Approach to Food Safety Education on the Farm

Food safety education from farm to end user is essential in the mitigation of food safety concerns associated with fresh produce. Iowa State University developed a multi-disciplinary three-level sequential program ( Know, Show, Go ) to provide a holistic approach to food safety education. This program provides knowledge on GAP (Know); guides development and documentation of food safety practices (Show); and aids in grower\u27s readiness for third party auditing (Go). Evaluations suggest this program is effective in changing long term food safety knowledge, attitude, and behaviors. The multi-disciplinary sequential approach can be used by other Extension programs to reach

The importance of tectonic setting in assessing European Rare Earth potential

Rare earth element (REE) resources are commonly found associated with alkaline igneous complexes or carbonatites, or as secondary deposits derived from igneous rocks. Globally, many REE deposits occur around the margins of Archaean cratons, most in continental rift zones. Europe contains many such rift zones, which are generally younger in the south. Many of these rifts are intracontinental, whereas others are associated with the opening of oceans such as the Atlantic. All these rift systems have the potential to host REE resources, but whereas the older provinces of northern Europe are deeply exposed, exposures in southern Europe are largely at the supracrustal level. This paper considers how an understanding of the tectonic setting of Europe’s REE resources is vital to guide future exploration

Ionized o-, m-, and p-Difluorobenzene Dissociate Through Ring-Opened Intermediates: A TPEPICO Investigation

Threshold photoelectron photoion coincidence (TPEPICO) experiments have shown that o-, m-, and p-difluorobenzene ions dissociate via a common, ring-opened intermediate and not via ionized p-difluorobenzene. Rice-Ramsperger-Kassel-Marcus (RRKM) modeling of the experimental breakdown curves yields activation energies for the initial isomerization of 4.48 ± 0.05, 4.55 ± 0.05, and 4.68 ± 0.05 eV for o-, m-, and p-difluorobenzene, respectively. These values place each ion at a similar absolute energy and thus similar transition states. A large positive ΔS‡ for each ion (ca 100 J K−1 mol−1) suggests a ring-opened structure for these transition states