Toxic metals in indoor dust collected from houses included in the “6x60x6” Project (Covilhã, Portugal) during the cooling season

We spend more than 90 per cent of our daily lives indoors. Managing the indoor environment so that we feel comfortable and healthy is therefore very important. However, this management is only possible if rigorous data on both construction parameters and indoor environment exists. Moreover, the evolution of construction techniques and materials used modulates both aspects. As a consequence, it is necessary that the information obtained reflects a long period of time. That is the main driver for the project “Six by Sixty by Six” undertaken by the Civil Engineering and Architecture Department and the Faculty of Health Sciences of the University of Beira Interior. Six houses constructed in six different decades (1960’s-2010’s) were surveyed for sixty days regarding a set of parameters (e.g., temperature, humidity, CO2, CO, VOCs). Additionally, dust was collected by the vacuum cleaner bag and was analyzed for specific contaminants. This work presents the results obtained for the toxics metals mercury, arsenic, cadmium, and lead in dust samples. There is no legislation regulating maximum permissible levels for any of the studied metals in dust. A comparison with ”Portaria Nº 1450/2007” which regulates the maximum metal contents in dredged sediment that can be safely deposited in soils (here used as an action threshold) reveals that the values for As in all houses were transcended. For Cd and Hg they were only transcended in one house, whereas for lead all the values were below this threshold. Linear regression with age of construction used as independent variable revealed no relationship between this variable and metal concentrations with the exception of As (R2 adjusted= 0.41). Findings are discussed under the light of potential health outcomes upon the residents.info:eu-repo/semantics/publishedVersio

Mercury levels in house dust samples from Covilhã, Portugal - Preliminary results from 6x60x6 Project

A avaliação da qualidade do ambiente interior, particularmente do ambiente doméstico, por ser aquele em que o ser humano passa a maior parte do seu tempo, reveste-se de particular importância. Esta qualidade é modulada por um conjunto de fatores entre os quais se encontram os contaminantes ambientais com potencial tóxico, que têm vindo a ser quantificados de forma consistente no pó doméstico, uma matriz com grande capacidade integradora. Este trabalho, que utiliza o mercúrio como caso de estudo, integra-se no âmbito de um projeto pioneiro e multidisciplinar, em que se pretende estudar por um período de sessenta dias, seis habitações particulares localizadas na cidade da Covilhã, para compreender de que forma as características do imóvel e os hábitos dos habitantes podem influenciar a qualidade do ambiente interior e consequentemente a saúde dos residentes. Os níveis de mercúrio total nas amostras de pó doméstico variaram entre 138,7 ppb e 1075,5 ppb, com um só dos imóveis a transcender o valor máximo permissível estabelecido pela Portaria Nº1450/2007. Estabelece-se uma comparação com os valores registados para outros estudos similares e traça-se um plano de ação para o pleno desenvolvimento do estudo.The evaluation of indoor environmental quality, particularly of households, is of paramount importance since modern humans spend most of their time indoors. Environmental contaminants with toxic potential play a central role in the modulation of indoor quality and recent trends have pointed towards their quantification in dust, which is a highly integrative matrix. The present work uses mercury as a case study integrated in a pioneering multidisciplinary study aiming to ascertain (by measuring a set of parameters for sixty days in six houses built in six different decades – 6x60x6) how the household characteristics and residents’ habits modulate indoor environmental quality and, in turn, drive impacts upon their health. Total mercury levels in house dust samples varied between 138.7 ppb and 1075.5 ppb, with a single house recording a value higher than the limit admissible by Portuguese law (Portaria Nº1450/2007). A comparison of the obtained values with similar studies worldwide is performed and an action plan for the full development of the study is drafted. Keywords: Indoor environment, Metals, Mercury, House dustinfo:eu-repo/semantics/publishedVersio

House dust fungal communities’ characterization: a double take on the six by sixty by six project (6x60x6)

Fungi are a group microbes, that are found with particular incidence in the indoor environment. Their direct toxicity or capability of generating toxic compounds has been associated with a large number of adverse health effects, such as infectious diseases, allergies and other toxic effects. Given that in modern society people spend a large part of their time indoors; fungal communities’ characterization of this environmental compartment assumes paramount importance in the comprehension of health effects. House dust is an easy to obtain, time-integrative matrix, being its use in epidemiological studies on human exposure to environmental contaminants highly recommended. Furthermore, dust can carry a great variety of fungal content that undergoes a large number of processes that modulate and further complexify human exposure. Our study aims to quantify and identify the fungal community on house dust samples collected using two different methodologies (an approach not often seen in the literature): active (vacuum cleaner bags) and passive sampling (dust settled in petri dishes). Sampling was performed as part of the ongoing 6x60x6 Project in which six houses from Covilhã (Portugal), with building dates representative of six decades, were studied for a period of sixty days.info:eu-repo/semantics/publishedVersio

Characteristics of the dietary consumption of patients with probable dementia of alzheimer type, at different stages: Observational study in a public outpatient clinic in São Paulo, Brazil

Purpose:to verify the correlation of the ingested diet with the nutritional status of Alzheimer disease (AD) patients; observation of fiber and fluid consumption and intestinal function. Methods: Cross-sectional study with 77 patients of both genders and their caregivers who were referred to nutritional status care in the three phases (CDR) of the AD. All answered the food anamnesis where it was possible to establish the amount of calories, macronutrients and micronutrients. Anthropometric measurements of weight, height, BMI, AC, TSF and AMC were collected.For the continuous variables, a descriptive statistical analysis was performed and for the analytical statistic the Poisson regression was used. Results:Most of the patients were eutrophic. The studied macronutrients were found to be adequate, except for the protein intake that was higher in the mild phase. No group achieved fiber intake. It was not found significant correlations between fiber consumption and intestinal function. In relation to micronutrients, adequate consumption of iron, vitamins A and B12 were found. Vitamin C intake did not reach DRI in mild patients and zinc consumption was low for patients who belonged to the group with moderated patients. Conclusions:Although it does not reflect the nutritional reality of Brazilian patients with probable AD, this study provided important characteristics of the diet composition that already allow us to establish nutritional action strategies.info:eu-repo/semantics/publishedVersio