22,240 research outputs found

    Radial honeycomb core

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    Core alleviates many limitations of conventional nacelle construction methods. Radical core, made of metals or nonmetals, is fabricated either by joining nodes and then expanding, or by performing each layer and then joining nodes. Core may also be produced from ribbons or strips with joined nodes or ribbons oriented in longitudinal planes

    Magnetic defects promote ferromagnetism in Zn1-xCoxO

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    Experimental studies of Zn1-xCoxO as thin films or nanocrystals have found ferromagnetism and Curie temperatures above room temperature and that p- or n-type doping of Zn1-xCoxO can change its magnetic state. Bulk Zn1-xCoxO with a low defect density and x in the range used in experimental thin film studies exhibits ferromagnetism only at very low temperatures. Therefore defects in thin film samples or nanocrystals may play an important role in promoting magnetic interactions between Co ions in Zn1-xCoxO. The electronic structures of Co substituted for Zn in ZnO, Zn and O vacancies, substituted N and interstitial Zn in ZnO were calculated using the B3LYP hybrid density functional in a supercell. The B3LYP functional predicts a band gap of 3.34 eV for bulk ZnO, close to the experimental value of 3.47 eV. Occupied minority spin Co 3d levels are at the top of the valence band and unoccupied levels lie above the conduction band minimum. Majority spin Co 3d levels hybridize strongly with bulk ZnO states. The neutral O vacancy and interstitial Zn are deep and shallow donors, respectively. The Zn vacancy is a deep acceptor and the acceptor level for substituted N is at mid gap. The possibility that p- or n-type dopants promote exchange coupling of Co ions was investigated by computing total energies of magnetic states of ZnO supercells containing two Co ions and an oxygen vacancy, substituted N or interstitial Zn in various charge states. The neutral N defect and the singly-positively charged O vacancy are the only defects which strongly promote ferromagnetic exchange coupling of Co ions at intermediate range.Comment: 9 pages, 11 figure

    Photometric study of selected cataclysmic variables

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    We present time-resolved photometry of five relatively poorly-studied cataclysmic variables: V1193 Ori, LQ Peg, LD 317, V795 Her, and MCT 2347-3144. The observations were made using four 1m-class telescopes for a total of more than 250 h of observation and almost 16,000 data points. For LQ Peg WHT spectroscopic data have been analysed as well. The light curves show a wide range of variability on different time scales from minutes to months. We detect for the first time a brightness variation of 0.05 mag in amplitude in V1193 Ori on the same timescale as the orbital period, which we interpret as the result of the irradiation of the secondary. A 20-min quasi-periodic oscillation is also detected. The mean brightness of the system has changed by 0.5 mag on a three-month interval, while the flickering was halved. In LQ Peg a 0.05 mag modulation was revealed with a period of about 3 h. The flickering was much smaller, of the order of 0.025 mag. A possible quasi-periodic oscillation could exist near 30 min. For this object, the WHT spectra are single-peaked and do not show any radial-velocity variations. The data of LD 317 show a decrease in the mean magnitude of the system. No periodic signal was detected but this is certainly attributable to the very large flickering observed: between 0.07 and 0.1 mag. For V795 Her, the 2.8-hour modulation, thought to be a superhump arising from the precession of the disc, is present. We show that this modulation is not stable in terms of periodicity, amplitude, and phase. Finally, for MCT 2347-3144, a clear modulation is seen in a first dataset obtained in October 2002. This modulation is absent in August 2003, when the system was brighter and showed much more flickering.Comment: 19 pages, 15 figures, 7 tables. Accepted for pubication by A&

    Intrabodies Binding the Proline-Rich Domains of Mutant Huntingtin Increase Its Turnover and Reduce Neurotoxicity

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    Although expanded polyglutamine (polyQ) repeats are inherently toxic, causing at least nine neurodegenerative diseases, the protein context determines which neurons are affected. The polyQ expansion that causes Huntington's disease (HD) is in the first exon (HDx-1) of huntingtin (Htt). However, other parts of the protein, including the 17 N-terminal amino acids and two proline (polyP) repeat domains, regulate the toxicity of mutant Htt. The role of the P-rich domain that is flanked by the polyP domains has not been explored. Using highly specific intracellular antibodies (intrabodies), we tested various epitopes for their roles in HDx-1 toxicity, aggregation, localization, and turnover. Three domains in the P-rich region (PRR) of HDx-1 are defined by intrabodies: MW7 binds the two polyP domains, and Happ1 and Happ3, two new intrabodies, bind the unique, P-rich epitope located between the two polyP epitopes. We find that the PRR-binding intrabodies, as well as VL12.3, which binds the N-terminal 17 aa, decrease the toxicity and aggregation of HDx-1, but they do so by different mechanisms. The PRR-binding intrabodies have no effect on Htt localization, but they cause a significant increase in the turnover rate of mutant Htt, which VL12.3 does not change. In contrast, expression of VL12.3 increases nuclear Htt. We propose that the PRR of mutant Htt regulates its stability, and that compromising this pathogenic epitope by intrabody binding represents a novel therapeutic strategy for treating HD. We also note that intrabody binding represents a powerful tool for determining the function of protein epitopes in living cells

    How expensive space-zero-gravity convection experiments can be carried out in terrestrial conditions – magnetic convection of a paramagnetic fluid

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    Over the last decade or so it has became possible to build high-temperature super-conducting magnets that operate in a laboratory environment. Many new phenomena connected with strong magnetic fields have been reported (e.g. promotion of combustion, magnetic levitation, separation methods for weakly magnetic materials etc.). There are many applications of the use of magnetic force on the Earth. For instance, knowing how to control such a force makes it possible to negate the influence of the gravitational force and study a particular phenomenon as it would occur in the Cosmos, but under terrestrial conditions, avoiding the need for expensive space travel. The use of a magnetic field may also help in many processes such as crystal growth, mixing and material processing. The present work is concerned with magnetic convection of a paramagnetic fluid in a cubical enclosure heated and cooled from the sidewalls. The influence of a 10-T magnetic field on the convection mode of the paramagnetic fluid and the heat transfer rate were investigated numerically and experimentally, and compared with gravitational natural convection. The present study clearly shows that natural convection can be enhanced, and the direction of the convection flow can be changed using a strong magnetic field in terrestrial conditions

    Feedback in a cavity QED system for control of quantum beats

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    Conditional measurements on the undriven mode of a two-mode cavity QED system prepare a coherent superposition of ground states which generate quantum beats. The continuous system drive induces decoherence through the phase interruptions from Rayleigh scattering, which manifests as a decrease of the beat amplitude and an increase of the frequency of oscillation. We report recent experiments that implement a simple feedback mechanism to protect the quantum beat. We continuously drive the system until a photon is detected, heralding the presence of a coherent superposition. We then turn off the drive and let the superposition evolve in the dark, protecting it against decoherence. At a later time we reinstate the drive to measure the amplitude, phase, and frequency of the beats. The amplitude can increase by more than fifty percent, while the frequency is unchanged by the feedback.Comment: 13 pages, 5 figures, ICAP 2012 23rd International Conference on Atomic Physic

    Evaluation of active control technology for short haul aircraft

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    An evaluation of the economics of short-haul aircraft designed with active controls technology and low wing-loading to achieve short field performance with good ride quality is presented. Results indicate that for such a system incorporating gust load alleviation and augmented stability the direct operating cost is better than for aircraft without active controls
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