Nonlinear disturbance evolution in a two-dimensional boundary layer along an elastic plate and induced radiated sound

The interaction between a boundary-layer flow and an elastic plate is addressed by direct numerical simulation, taking into account the full coupling between the fluid flow and the flexible wall. The convectively unstable flow state is harmonically forced and two-dimensional nonlinearly saturated wavelike disturbances are computed along archetype-plates with respect to stiffness and natural frequencies. In the aim of determining the low-Mach-number radiated sound for the system, the simulation data are used to solve the Lighthill’s equation in terms of a Green’s function in the wavenumber-frequency space. Different degrees of fluid-structure coupling are implemented in the radiated sound model and the resulting acoustic pressure levels are compared. The sound radiation levels are shown to be increased in the presence of flexible walls with however significant differences in the radiated pressure levels for different coupling assumptionsThe authors gratefully acknowledge Thales Underwater Systems and DCNS for their financial support to this work

Dynamic Behaviour of a Flexible Yacht Sail Plan

• Dynamic fluid structure interaction of a sail plan is modeled in harmonic pitching • Aerodynamic forces oscillations show hysteresis phenomena • Neglecting the structural deformation underestimates the forces oscillations • Both aerodynamic and structure inertia affect loads in the rig.A numerical investigation of the dynamic Fluid Structure Interaction (FSI) of a yacht sail plan submitted to harmonic pitching is presented to address both issues of aerodynamic unsteadiness and structural deformation. The FSI model | Vortex Lattice Method uid model and Finite Element structure model | has been validated with full-scale measurements. It is shown that the dynamic behaviour of a sail plan subject to yacht motion clearly deviates from the quasi-steady theory. The aerodynamic forces presented as a function of the instantaneous apparent wind angle show hysteresis loops, suggesting that some energy is exchanged by the system. The area included in the hysteresis loop increases with the motion reduced frequency and amplitude. Comparison of rigid versus soft structures shows that FSI increases the energy exchanged by the system and that the oscillations of aerodynamic forces are underestimated when the structure deformation is not considered. Dynamic loads in the fore and aft rigging wires are dominated by structural and inertial effects. This FSI model and the obtained results may be useful firstly for yacht design, and also in the field of auxiliary wind assisted ship propulsion, or to investigate other marine soft structures.This work was supported by the French Naval Academy

Nonlinear disturbance evolution in a boundary layer along an elastic plate and induced radiated sound

The interaction between a boundary-layer flow and an elastic plate is addressed by direct numerical simulation, taking into account the full coupling between the fluid flow and the flexible wall. The convectively unstable flow state is harmonically forced and two-dimensional nonlinearly saturated wavelike disturbances are computed along archetype-plates with respect to stiffness and natural frequencies. In the aim of determining the low-Mach-number radiated sound for the system, the simulation data are used to solve the Lighthill’s equation in terms of a Green’s function in the wavenumber-frequency space.Different degrees of fluid-structure coupling are implemented in the radiated sound model and the resulting acoustic pressure levels are compared. The sound radiation levels are shown to be increased in the presence of flexible walls with however significant differences in the radiated pressure levels for different coupling assumptionsInternational audienceThe interaction between a boundary-layer flow and an elastic plate is addressed by direct numerical simulation, taking into account the full coupling between the fluid flow and the flexible wall. The convectively unstable flow state is harmonically forced and two-dimensional nonlinearly saturated wavelike disturbances are computed along archetype-plates with respect to stiffness and natural frequencies. In the aim of determining the low-Mach-number radiated sound for the system, the simulation data are used to solve the Lighthill’s equation in terms of a Green’s function in the wavenumber-frequency space.Different degrees of fluid-structure coupling are implemented in the radiated sound model and the resulting acoustic pressure levels are compared. The sound radiation levels are shown to be increased in the presence of flexible walls with however significant differences in the radiated pressure levels for different coupling assumption

Transducteur adapté à la génération de forces en fonction de la vitesse d'écoulement d'un fluide

L’invention concerne un dispositif détecteur d’une vitesse seuil de déplacement d’un fluide, le dispositif détecteur comprenant un transducteur et configuré pour exercer une première force non nulle dans une première direction lorsque la vitesse du fluide est inférieure à la vitesse seuil et pour exercer une seconde force non nulle dans une seconde direction lorsque la vitesse du fluide est supérieure à la vitesse seuil , la première et la seconde direction étant identiques ou sensiblement identiques et la première et la deuxième force étant dirigées dans des sens opposés

Transducteur adapté à la génération de forces en fonction de la vitesse d'écoulement d'un fluide

L’invention concerne un dispositif détecteur d’une vitesse seuil de déplacement d’un fluide, le dispositif détecteur comprenant un transducteur et configuré pour exercer une première force non nulle dans une première direction lorsque la vitesse du fluide est inférieure à la vitesse seuil et pour exercer une seconde force non nulle dans une seconde direction lorsque la vitesse du fluide est supérieure à la vitesse seuil , la première et la seconde direction étant identiques ou sensiblement identiques et la première et la deuxième force étant dirigées dans des sens opposés

Experimental validation of unsteady models for wind / sails / rigging fluid structure interaction

International audienceThe aim of this paper is to present the work of experimental validation elements of the aero elastic and unsteady model ARAVANTI. Numerical and Experimental results comparison is made on the rigging and sails of a J80 sail boat. Yacht modelling demands to consider unsteady phenomena resulting from the sea state, variations of wind speed and direction, yacht motion or trimming by the crew. A dedicated instrumentation is developed to measure the loads in shrouds and tension points of the sail, the apparent wind, the yacht motion, the sails flying shape and the navigation data. A special effort is made on sensors calibration, physical measurement comprehension and data synchronisation. Comparison with numerical results shows that the loads and flying shapes are well predicted by the model

Pre-hospital management protocols and perceived difficulty in diagnosing acute heart failure

Aim To illustrate the pre-hospital management arsenals and protocols in different EMS units, and to estimate the perceived difficulty of diagnosing suspected acute heart failure (AHF) compared with other common pre-hospital conditions. Methods and results A multinational survey included 104 emergency medical service (EMS) regions from 18 countries. Diagnostic and therapeutic arsenals related to AHF management were reported for each type of EMS unit. The prevalence and contents of management protocols for common medical conditions treated pre-hospitally was collected. The perceived difficulty of diagnosing AHF and other medical conditions by emergency medical dispatchers and EMS personnel was interrogated. Ultrasound devices and point-of-care testing were available in advanced life support and helicopter EMS units in fewer than 25% of EMS regions. AHF protocols were present in 80.8% of regions. Protocols for ST-elevation myocardial infarction, chest pain, and dyspnoea were present in 95.2, 80.8, and 76.0% of EMS regions, respectively. Protocolized diagnostic actions for AHF management included 12-lead electrocardiogram (92.1% of regions), ultrasound examination (16.0%), and point-of-care testings for troponin and BNP (6.0 and 3.5%). Therapeutic actions included supplementary oxygen (93.2%), non-invasive ventilation (80.7%), intravenous furosemide, opiates, nitroglycerine (69.0, 68.6, and 57.0%), and intubation 71.5%. Diagnosing suspected AHF was considered easy to moderate by EMS personnel and moderate to difficult by emergency medical dispatchers (without significant differences between de novo and decompensated heart failure). In both settings, diagnosis of suspected AHF was considered easier than pulmonary embolism and more difficult than ST-elevation myocardial infarction, asthma, and stroke. Conclusions The prevalence of AHF protocols is rather high but the contents seem to vary. Difficulty of diagnosing suspected AHF seems to be moderate compared with other pre-hospital conditions

Experimental validation of unsteady models for wind / sails / rigging fluid structure interaction

The aim of this paper is to present the work of experimental validation elements of the aero elastic and unsteady model ARAVANTI. Numerical and Experimental results comparison is made on the rigging and sails of a J80 sail boat. Yacht modelling demands to consider unsteady phenomena resulting from the sea state, variations of wind speed and direction, yacht motion or trimming by the crew. A dedicated instrumentation is developed to measure the loads in shrouds and tension points of the sail, the apparent wind, the yacht motion, the sails flying shape and the navigation data. A special effort is made on sensors calibration, physical measurement comprehension and data synchronisation. Comparison with numerical results shows that the loads and flying shapes are well predicted by the model

Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression

Many workers are daily exposed to occupational agents like gases/fumes, mineral dust or biological dust, which could induce adverse health effects. Epigenetic mechanisms, such as DNA methylation, have been suggested to play a role. We therefore aimed to identify differentially methylated regions (DMRs) upon occupational exposures in never-smokers and investigated if these DMRs associated with gene expression levels. To determine the effects of occupational exposures independent of smoking, 903 never-smokers of the LifeLines cohort study were included. We performed three genome-wide methylation analyses (Illumina 450 K), one per occupational exposure being gases/fumes, mineral dust and biological dust, using robust linear regression adjusted for appropriate confounders. DMRs were identified using comb-p in Python. Results were validated in the Rotterdam Study (233 never-smokers) and methylation-expression associations were assessed using Biobank-based Integrative Omics Study data (n = 2802). Of the total 21 significant DMRs, 14 DMRs were associated with gases/fumes and 7 with mineral dust. Three of these DMRs were associated with both exposures (RPLP1 and LINC02169 (2x)) and 11 DMRs were located within transcript start sites of gene expression regulating genes. We replicated two DMRs with gases/fumes (VTRNA2-1 and GNAS) and one with mineral dust (CCDC144NL). In addition, nine gases/fumes DMRs and six mineral dust DMRs significantly associated with gene expression levels. Our data suggest that occupational exposures may induce differential methylation of gene expression regulating genes and thereby may induce adverse health effects. Given the millions of workers that are exposed daily to occupational exposures, further studies on this epigenetic mechanism and health outcomes are warranted

Study protocol: Population screening for colorectal cancer by colonoscopy or CT colonography: A randomized controlled trial

Background: Colorectal cancer (CRC) is the second most prevalent type of cancer in Europe. Early detection and removal of CRC or its precursor lesions by population screening can reduce mortality. Colonoscopy and computed tomography colonography (CT colonography) are highly accurate exams and screening options that examine the entire colon. The success of screening depends on the participation rate. We designed a randomized trial to compare the uptake, yield and costs of direct colonoscopy population screening, using either a telephone consultation or a consultation at the outpatient clinic, versus CT colonography first, with colonoscopy in CT colonography positives.Methods and design: 7,500 persons between 50 and 75 years will be randomly selected from the electronic database of the municipal administration registration and will receive an invitation to participate in either CT colonography (2,500 persons) or colonoscopy (5,000 persons) screening. Those invited for colonoscopy screening will be randomized to a prior consultation either by telephone or a visit at the outpatient clinic. All CT colonography invitees will have a prior consultation by telephone. Invitees are instructed to consult their general practitioner and not to participate in screening if they have symptoms suggestive for CRC. After provid