Looking Beyond the Marketing Claims of New Beverages: Health Risks of Consuming Sports Drinks, Energy Drinks, Fortified Waters, and Other Flavored Beverages

Consumption of several new categories of beverages has increased significantly in recent years. Sold in cans and bottles in many venues and heavily marketed as health and strength enhancing, these beverages have become popular among children and adolescents as well as adults. Energy drinks, sports drinks, fruit drinks, flavored waters, and sweetened teas and coffees are known collectively as fortified beverages due to the natural and artificial ingredients that are added in the processing of their main ingredient, water. In view of their rising popularity, it is important to assess the healthfulness of these beverages and the implications of their consumption by the general public. Consumption by youth, to whom marketing is often targeted, is of particular interest in view of children's potentially increased vulnerability to chemicals and other added substances. Further, the possible contribution of these beverages to the high prevalence of childhood obesity merits attention.This report will discuss the major categories of fortified beverages, presenting data on their nature, their ingredients, their similarities and differences, the possible effects on children of their consumption, and areas for further research

Illinois: An Assessment of Access to Counsel & Quality or Representation in Delinquency Proceedings

Examines the scope and quality of legal representation of accused children in juvenile courts throughout the state and provides recommendations for strengthening the quality of defender services for children

A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits.

Corticotrophin-releasing factor (CRF) is a 41 amino acid neuropeptide that coordinates adaptive responses to stress. CRF projections from neurons in the central nucleus of the amygdala (CeA) to the brainstem are of particular interest for their role in motivated behavior. To directly examine the anatomy and function of CRF neurons, we generated a BAC transgenic Crh-Cre rat in which bacterial Cre recombinase is expressed from the Crh promoter. Using Cre-dependent reporters, we found that Cre expressing neurons in these rats are immunoreactive for CRF and are clustered in the lateral CeA (CeL) and the oval nucleus of the BNST. We detected major projections from CeA CRF neurons to parabrachial nuclei and the locus coeruleus, dorsal and ventral BNST, and more minor projections to lateral portions of the substantia nigra, ventral tegmental area, and lateral hypothalamus. Optogenetic stimulation of CeA CRF neurons evoked GABA-ergic responses in 11% of non-CRF neurons in the medial CeA (CeM) and 44% of non-CRF neurons in the CeL. Chemogenetic stimulation of CeA CRF neurons induced Fos in a similar proportion of non-CRF CeM neurons but a smaller proportion of non-CRF CeL neurons. The CRF1 receptor antagonist R121919 reduced this Fos induction by two-thirds in these regions. These results indicate that CeL CRF neurons provide both local inhibitory GABA and excitatory CRF signals to other CeA neurons, and demonstrate the value of the Crh-Cre rat as a tool for studying circuit function and physiology of CRF neurons

Connectivity Series at RIT- Developing & Delivering an Effective Professional Development Workshop Series for Women Faculty in STEM

In science, technology, engineering and math (STEM) disciplines within the United States; women faculty are underrepresented within many disciplines including engineering, computer science, and physics. At a large private university, RIT, the ADVANCE institutional transformation project (supported by NSF Award No. 1209115), referred to as Advance RIT, aims to increase the representation and advancement of women STEM faculty (which includes social and behavioral sciences, SBS) by removing barriers to resources that support career success and by creating new interventions and resources. This paper reports on the design, delivery and evaluation of a professional development workshop series, called the Connectivity Series, which is a vital initiative within this large-scale, multi-year, strategic institutional transformation project. The workshop series consists of programs to promote the recruitment, retention, and advancement of women faculty. The project team developed workshop themes based upon the results of a faculty climate survey and a literature review as part of a previously conducted NSF ADVANCE funded self-study (0811076). Project researchers created the Connectivity Series for all tenure-track women faculty on campus as well as targeted workshops for women of color and deaf and hard of hearing women faculty. All disciplines represented within the university (STEM and non-STEM) have been identified as the target audience for workshop offerings due to the high prevalence of STEM disciplines within the university. Program assessment and evaluation results are presented. In addition, a sustainability plan is outlined for continuation of these targeted workshops beyond the five-year grant funding period

Leptonic and Semileptonic Decays of Charm and Bottom Hadrons

We review the experimental measurements and theoretical descriptions of leptonic and semileptonic decays of particles containing a single heavy quark, either charm or bottom. Measurements of bottom semileptonic decays are used to determine the magnitudes of two fundamental parameters of the standard model, the Cabibbo-Kobayashi-Maskawa matrix elements $V_{cb}$ and $V_{ub}$. These parameters are connected with the physics of quark flavor and mass, and they have important implications for the breakdown of CP symmetry. To extract precise values of $|V_{cb}|$ and $|V_{ub}|$ from measurements, however, requires a good understanding of the decay dynamics. Measurements of both charm and bottom decay distributions provide information on the interactions governing these processes. The underlying weak transition in each case is relatively simple, but the strong interactions that bind the quarks into hadrons introduce complications. We also discuss new theoretical approaches, especially heavy-quark effective theory and lattice QCD, which are providing insights and predictions now being tested by experiment. An international effort at many laboratories will rapidly advance knowledge of this physics during the next decade.Comment: This review article will be published in Reviews of Modern Physics in the fall, 1995. This file contains only the abstract and the table of contents. The full 168-page document including 47 figures is available at http://charm.physics.ucsb.edu/papers/slrevtex.p