94 research outputs found

    Rumination on Chronopoetics and the Political Subject: Miraji Reads Faiz Ahmed Faiz’s Lyric

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    Using the poet Miraji’s short exegesis of the Faiz’s poem IntebÄh (warning or alarm), popularly known by its opening word , bol (speak), this paper will parse a small entry into Faiz’s poetics.  What did this curious imbrication of modernist exegesis with political poetics allow us to see?  In this paper I suggest that Miraji’s analysis allows us to see anew the ways in which romantic realism, fleshed politics and chronopoetics come together to give us another take on Faiz’s luminous corpus

    The psychosocial impact of breast cancer diagnosis and treatment in black and south asian women

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    Breast cancer is the most common form of cancer in women of all ethnic groups. The diagnosis and treatment of the disease can be challenging and distressing for any individual. Research in this area has documented a range of physical, psychological and social consequences. However, very little work within the existing literature captures the experiences of Black and Minority Ethnic (BME) women, especially in the UK. The limited available research, based on American studies, show that while similarities in White and BME women’s breast cancer experiences exist, there are also aspects that are unique and specific to BME women, which are influenced by socio-cultural norms, behaviours and beliefs. Therefore, the aim of this research was to explore the psychosocial impact of breast cancer diagnosis and treatment in British Black and South Asian women. To research this area, a qualitatively driven mixed method approach was adopted. Four studies were undertaken, 3 qualitative and 1 quantitative. The first study was exploratory in nature, in which semi-structured one-to-one interviews were carried out with 11 Black and 11 South Asian women. The findings of this study informed the subsequent studies, the second of which consisted of focus group interviews with 10 Black and 10 South Asian women to explore the ways in which breast cancer experiences are managed. The third study involved interviews with 5 South Asian Indian, Gujarati-speaking women (with limited English proficiency). The findings from these studies show that psychosocial and cultural factors (such as support, appearance concerns, healthcare experiences, cultural beliefs about cancer, understanding of cancer and language barriers) play an important role in shaping BME women’s experiences of breast cancer. These findings informed the development of the final questionnaire study. This study investigated the psychosocial impact of breast cancer and aimed to compare breast cancer experiences between White, Black and South Asian women. A total of 173 women participated (80 White, 40 Black and 53 South Asian). The results from this study show that psychological distress, social support and receiving chemotherapy treatment are associated with quality of life. Furthermore, similarities and differences in Black, South Asian and White women’s breast cancer experiences (in relation to psychological distress, quality of life, control beliefs (pertaining to cancer), body image concerns and sources of support) are evident. The findings from this research highlight important implications for policy makers, healthcare professionals and researchers to enhance awareness and understanding, and to ensure the provision of culturally competent care and support to future breast cancer patients

    The psychosocial impact of breast cancer diagnosis and treatment in Black and South Asian women

    Get PDF
    Breast cancer is the most common form of cancer in women of all ethnic groups. The diagnosis and treatment of the disease can be challenging and distressing for any individual. Research in this area has documented a range of physical, psychological and social consequences. However, very little work within the existing literature captures the experiences of Black and Minority Ethnic (BME) women, especially in the UK. The limited available research, based on American studies, show that while similarities in White and BME women’s breast cancer experiences exist, there are also aspects that are unique and specific to BME women, which are influenced by socio-cultural norms, behaviours and beliefs. Therefore, the aim of this research was to explore the psychosocial impact of breast cancer diagnosis and treatment in British Black and South Asian women. To research this area, a qualitatively driven mixed method approach was adopted. Four studies were undertaken, 3 qualitative and 1 quantitative. The first study was exploratory in nature, in which semi-structured one-to-one interviews were carried out with 11 Black and 11 South Asian women. The findings of this study informed the subsequent studies, the second of which consisted of focus group interviews with 10 Black and 10 South Asian women to explore the ways in which breast cancer experiences are managed. The third study involved interviews with 5 South Asian Indian, Gujarati-speaking women (with limited English proficiency). The findings from these studies show that psychosocial and cultural factors (such as support, appearance concerns, healthcare experiences, cultural beliefs about cancer, understanding of cancer and language barriers) play an important role in shaping BME women’s experiences of breast cancer. These findings informed the development of the final questionnaire study. This study investigated the psychosocial impact of breast cancer and aimed to compare breast cancer experiences between White, Black and South Asian women. A total of 173 women participated (80 White, 40 Black and 53 South Asian). The results from this study show that psychological distress, social support and receiving chemotherapy treatment are associated with quality of life. Furthermore, similarities and differences in Black, South Asian and White women’s breast cancer experiences (in relation to psychological distress, quality of life, control beliefs (pertaining to cancer), body image concerns and sources of support) are evident. The findings from this research highlight important implications for policy makers, healthcare professionals and researchers to enhance awareness and understanding, and to ensure the provision of culturally competent care and support to future breast cancer patients.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

    Modeling of Rainfall-Runoff Correlations Using Artificial Neural Network-A Case Study of Dharoi Watershed of a Sabarmati River Basin, India

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    The use of an Artificial Neural Network (ANN) is becoming common due to its ability to analyse complex nonlinear events. An ANN has a flexible, convenient and easy mathematical structure to identify the nonlinear relationships between input and output data sets. This capability could efficiently be employed for the different hydrological models such as rainfall-runoff models, which are inherently nonlinear in nature. Artificial Neural Networks (ANN) can be used in cases where the available data is limited. The present work involves the development of an ANN model using Feed-Forward Back Propagation algorithm for establishing monthly and annual rainfall runoff correlations. The hydrologic variables used were monthly and annual rainfall and runoff for monthly and annual time period of monsoon season. The ANN model developed in this study is applied to Dharoi reservoir watersheds of Sabarmati river basin of India. The hydrologic data were available for twenty-nine years at Dharoi station at Dharoi dam project. The model results yielding into the least error is recommended for simulating the rainfall-runoff characteristics of the watersheds. The obtained results can help the water resource managers to operate the reservoir properly in the case of extreme events such as flooding and drought

    The psychosocial impact of breast cancer diagnosis and treatment amongst Black, South Asian and White women: Do differences exist between ethnic groups?

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    Breast cancer is the most commonly diagnosed cancer in females, affecting women of all ethnic groups. Until now, very little research has captured the psychosocial impact of the disease amongst Black and Minority Ethnic (BME) women, and that which has been conducted has been restricted to English-speaking participants. The aim of this qualitative study was to explore the experiences of five Gujarati-speaking Indian women with regard to their breast cancer diagnosis and treatment; all five had Limited English Proficiency (LEP) and lived in the UK. Individual semi-structured interviews were conducted in Gujarati, with the assistance of an interpreter. Interpretative Phenomenological Analysis (IPA) of the data revealed 3 key themes: making sense of the cancer, importance of support and body image concerns. The findings show that these women’s experiences were influenced by culturally specific concerns, especially in relation to knowledge of breast cancer and language barriers. This study has implications for healthcare professionals in terms of providing culturally competent care and support to BME women with LEP

    FORMULATION AND EVALUATION OF ACYCLOVIR LOADED NOVEL NANO-EMULSION GEL FOR TOPICAL TREATMENT OF HERPES SIMPLEX VIRAL INFECTIONS

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    Acyclovir has low bioavailability mainly due to low solubility. This study aimed to formulate an optimized acyclovir (ACV) nanoemulsion gel for the slow, variable and incomplete oral drug absorption in patient suffering from herpes simplex viral infection. The dispersion solubility of acyclovir was studied in various oils, surfactants and co-surfactants and by constructing pseudo phase ternary diagram nanoemulsion area was identified. The optimized formulations of nanoemulsions were subjected to thermodynamic stability tests. After stability study, stable formulation was characterized for droplet size, pH determination, centrifugation, % drug content in nanoemulsion, Zeta Potential and Vesicle size measurement and than nanoemulsion gel were prepared and characterized for spreadability, measurement of viscosity, drug content, In-vitro diffusion, in-vitro release data. Span 40 was selected as surfactant, PEG 400 as co surfactant and castor oil as oil component based on solubility study. The in vitro drug release from acyclovir nanoemulsion gel was found to be considerably higher in comparison to that of the pure drug. The in-vitro diffusion of nanoemulsion gel was significantly good. Based on this study, it can be concluded the solubility and permeability of acyclovir can be increased by formulating into nanoemulsion gel. Keywords: Acyclovir, Nanoemulsion, In-vitro diffusion, Zeta potential, Stabilit

    Kinetics of transcription initiation at lacP1: multiple roles of cyclic amp receptor protein

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    The cyclic AMP receptor protein (CRP) acts as a transcription activator at many promoters of Escherichia coli. We have examined the kinetics of open complex formation at the lacP1 promoter using tryptophan fluorescence of RNA polymerase and DNA fragments with 2-aminopurine substituted at specific positions. Apart from the closed complex formation and promoter clearance, we were able to detect three steps. The first step after the closed complex formation leads to a rapid increase of 2-aminopurine fluorescence. This was followed by another rapid step in which quenching of tryptophan fluorescence of RNA polymerase was observed. The slowest step detected by 2-aminopurine fluorescence increase is assigned to the final open complex formation. We have found that CRP not only enhances RNA polymerase binding at the promoter, but also enhances the slowest isomerization step by about 2-fold. Furthermore, potassium permanganate probing shows that the conformation of the open complex in the presence of CRP appears qualitatively and quantitatively different from that in the absence of CRP, suggesting that contact with RNA polymerase is maintained throughout the transcription initiation

    Internet Addiction and Its Correlates among College Students of Surat City: A Cross Sectional Study

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    Introduction: The number of internet users in 2018 was 4.021 billion, increased 7 percent year-on-year. More than nine-tenths of Indian teens use Internet. Due to social distancing norms put forward due to COVID-19 dependency and availability of Internet usage has increased.Objective: To assess the extent of Internet addiction and determine its predictors among college students of Surat city. Method: A cross sectional study was conducted from March-September 2021 among 400 first- and second-year students selected by systematic random sampling from four colleges selected purposively. Outcome variables were Young’s Internet addiction Test and Duke Health Profile Score which were assessed in terms of mean score. Univariate analysis was done, followed by t-test, ANOVA and Pearson Correlation to establish associations. Predictors were determined by Binary Logistic Regression.Results: Around one-tenth (12.8%) participants were seen with no Internet addiction, with majority being mildly (44.8%) and moderately (36.5%) addicted. Severe addiction was seen in around one out of twenty participants (6.1%). Social networking (32%) and education (34.5%) were the major reasons for use of Internet. Higher pocket money (aOR=4.3), greater monthly internet expenditure (aOR=2.8), ownership of internet enabled mobile phone (aOR=3.9), lying down posture while accessing internet (aOR=4.8) and evening (aOR=2.2) or night time (aOR=8.7) of internet access were significant predictors for Internet addicts. Conclusion: In this study more than four fifth of the college students had Internet Addiction even at young age. Physical, Mental, Social and General health were significantly negatively correlated with internet addiction
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