44,335 research outputs found
Singularity Free Inhomogeneous Models with Heat Flow
We present a class of singularity free exact cosmological solutions of
Einstein's equations describing a perfect fluid with heat flow. It is obtained
as generalization of the Senovilla class [1] corresponding to incoherent
radiation field. The spacetime is cylindrically symmetric and globally regular.Comment: 6 pages, TeX, to appear in Class.Quant.Gra
Distress in a Hill and Remedial Measures
The paper presents a case study of a hill which developed signs of distress in 1979-80. Retaining and breast walls provided at many locations on the hill had been damaged and laterally shifted, indicating some movement in the hill. It created anxiety since big water tanks were supported on top of the bill. The distress in the bill were attributed to poor drainage of hill water, weaker sections of walls, dumping of loose lateritic material on the slopes, formation of erosion gullies etc. The bill was stabilized by removing these signs of distress with suitable remedial measures which are functioning satisfactorily over last 5-6 years. Systematic photographic presentation of different portions/features of the bill which showed signs of distress and then of different remedial measures which proved satisfactory makes the case study very interesting
TRAVOS: Trust and Reputation in the Context of Inaccurate Information Sources
In many dynamic open systems, agents have to interact with one another to achieve their goals. Here, agents may be self-interested, and when trusted to perform an action for another, may betray that trust by not performing the action as required. In addition, due to the size of such systems, agents will often interact with other agents with which they have little or no past experience. There is therefore a need to develop a model of trust and reputation that will ensure good interactions among software agents in large scale open systems. Against this background, we have developed TRAVOS (Trust and Reputation model for Agent-based Virtual OrganisationS) which models an agent's trust in an interaction partner. Specifically, trust is calculated using probability theory taking account of past interactions between agents, and when there is a lack of personal experience between agents, the model draws upon reputation information gathered from third parties. In this latter case, we pay particular attention to handling the possibility that reputation information may be inaccurate
Nanoscale electrochemical patterning reveals the active sites for catechol oxidation at graphite surfaces
Graphite-based electrodes (graphite, graphene, and nanotubes) are used widely in electrochemistry, and there is a long-standing view that graphite step edges are needed to catalyze many reactions, with the basal surface considered to be inert. In the present work, this model was tested directly for the first time using scanning electrochemical cell microscopy reactive patterning and shown to be incorrect. For the electro-oxidation of dopamine as a model process, the reaction rate was measured at high spatial resolution across a surface of highly oriented pyrolytic graphite. Oxidation products left behind in a pattern defined by the scanned electrochemical cell served as surface-site markers, allowing the electrochemical activity to be correlated directly with the graphite structure on the nanoscale. This process produced tens of thousands of electrochemical measurements at different locations across the basal surface, unambiguously revealing it to be highly electrochemically active, with step edges providing no enhanced activity. This new model of graphite electrodes has significant implications for the design of carbon-based biosensors, and the results are additionally important for understanding electrochemical processes on related sp2-hybridized materials such as pristine graphene and nanotubes
Formulation and Evaluation of Floating Oral In Situ Gelling System of Amoxicillin
Purpose. Effective Helicobacter pylori eradication requires delivery of the antibiotic locally in the stomach. High dose of amoxicillin (750 to 1000 mg) is difficult to incorporate in floating tablets but can easily be given in liquid dosage form. Keeping the above facts in mind, we made an attempt to develop a new floating in situ gelling system of amoxicillin with increased residence time using sodium alginate as gelling polymer to eradicate H. pylori. Methods. Floating in situ gelling formulations were prepared using sodium alginate, calcium chloride, sodium citrate, hydroxypropyl methyl cellulose K100, and sodium bicarbonate. The prepared formulations were evaluated for solution viscosity, floating lag time, total floating time, and in vitro drug release. The formulation was optimized using a 32 full factorial design. Dissolution data were fitted to various models to ascertain kinetic of drug release. Regression analysis and analysis of variance were performed for dependent variables. Results. All formulations (F1–F9) showed floating within 30 s and had total floating time of more than 24 h. All the formulations showed good pourability. It was observed that concentration of sodium alginate and HPMC K100 had significant influence on floating lag time, cumulative percentage drug release in 6 h and 10 h. The batch F8 was considered optimum since it showed more similarity in drug release (f2 = 74.38) to the theoretical release profile. Conclusion. Floating in situ gelling system of amoxicillin can be formulated using sodium alginate as a gelling polymer to sustain the drug release for 10 to 12 h with zero-order release kinetics
CO J = 2 - 1 Emission from Evolved Stars in the Galactic Bulge
We observe a sample of 8 evolved stars in the Galactic Bulge in the CO J = 2
- 1 line using the Submillimeter Array (SMA) with angular resolution of 1 - 4
arcseconds. These stars have been detected previously at infrared wavelengths,
and several of them have OH maser emission. We detect CO J = 2 - 1 emission
from three of the sources in the sample: OH 359.943 +0.260, [SLO2003] A12, and
[SLO2003] A51. We do not detect the remaining 5 stars in the sample because of
heavy contamination from the galactic foreground CO emission. Combining CO data
with observations at infrared wavelengths constraining dust mass loss from
these stars, we determine the gas-to-dust ratios of the Galactic Bulge stars
for which CO emission is detected. For OH 359.943 +0.260, we determine a gas
mass-loss rate of 7.9 (+/- 2.2) x 10^-5 M_Sun/year and a gas-to-dust ratio of
310 (+/- 89). For [SLO2003] A12, we find a gas mass-loss rate of 5.4 (+/- 2.8)
x 10^-5 M_Sun/year and a gas-to-dust ratio of 220 (+/- 110). For [SLO2003] A51,
we find a gas mass-loss rate of 3.4 (+/- 3.0) x 10^-5 M_Sun/year and a
gas-to-dust ratio of 160 (+/- 140), reflecting the low quality of our tentative
detection of the CO J = 2 - 1 emission from A51. We find the CO J = 2 - 1
detections of OH/IR stars in the Galactic Bulge require lower average CO J = 2
- 1 backgrounds.Comment: 40 pages, 16 figures, appeared in the 1 March 2013 issue of the
Astrophysical Journa
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