2,770 research outputs found

    A Duty to Resist: When Disobedience Should Be Uncivil

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    Group Rights in Liberalism's Religion - CĂ©cile Laborde: Liberalism's Religion (Cambridge, MA: Harvard University Press, 2017. Pp. 344)

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    Chapter 5 of Laborde’s incredibly rich analysis engages with the question of religious group rights. Laborde argues that the politically liberal state should grant (some) religious associations legal exemptions and protections, on the basis of their freedom-of-association-related interests: first, their coherence interest in living “by their own standards, purposes and commitments,” and second, their competence interest in being allowed to “interpret their own standards, purposes and commitments” (175). Accordingly, religious associations may be exempt from gender discrimination laws, if compliance would prevent them from acting as their religious doctrine requires them to (189). I offer two critical comments on Laborde’s account. My first concerns her treatment of ontological issues as irrelevant to group rights. The second concerns the scope of rights she is willing to grant religious associations

    Hippocampal subfields and limbic white matter jointly predict learning rate in older adults

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    First published online: 04 December 2019Age-related memory impairments have been linked to differences in structural brain parameters, including cerebral white matter (WM) microstructure and hippocampal (HC) volume, but their combined influences are rarely investigated. In a population-based sample of 337 older participants aged 61-82 years (Mage = 69.66, SDage = 3.92 years), we modeled the independent and joint effects of limbic WM microstructure and HC subfield volumes on verbal learning. Participants completed a verbal learning task of recall over five repeated trials and underwent magnetic resonance imaging (MRI), including structural and diffusion scans. We segmented three HC subregions on high-resolution MRI data and sampled mean fractional anisotropy (FA) from bilateral limbic WM tracts identified via deterministic fiber tractography. Using structural equation modeling, we evaluated the associations between learning rate and latent factors representing FA sampled from limbic WM tracts, and HC subfield volumes, and their latent interaction. Results showed limbic WM and the interaction of HC and WM-but not HC volume alone-predicted verbal learning rates. Model decomposition revealed HC volume is only positively associated with learning rate in individuals with higher WM anisotropy. We conclude that the structural characteristics of limbic WM regions and HC volume jointly contribute to verbal learning in older adults

    Induction of Resistance Against Isotransplantation of Virus-Induced Myeloid Leukaemias

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    ALL the experiments carried out in various laboratories since the publicatioil

    Interstitial cells of Cajal — systematic review

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    This paper reviews the distribution of interstitial cells of Cajal (ICC) in the human gastro­intestinal (GI) tract, based on ultrastructural and immunohistochemical evidence. The distribution and morphology of ICC at each level of the normal GI tracts is addressed from the perspective of their functional significance. Alterations of ICC reported in as well as in GI stromal tumours are reviewed, with emphasis on the place of ICC in the pathophysiology of disease

    Unusual variations in the branching pattern of the coeliac trunk and their clinical significance

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    Background: The anatomical variations of the coeliac trunk are due to developmental changes in the ventral segmental arteries. Multidetector computed tomography (MDCT) has been used to investigate vascular anatomy for scientific and diagnostic purposes. These studies allow for much larger sample sizes than traditional cadaveric studies. The aim of this research was to isolate rare anatomical variants of the coeliac trunk and emphasize their clinical significance. Materials and methods: A descriptive, retrospective study was carried out on MDCT angiographies performed from January 2020 till March 2020 in Polish patients. Coeliac trunk was studied and normal and anatomical variations were identified. Results: Out of total 350 patients, hepatogastrosplenic trunk was predominant. However, we observed: coeliaco-mesenteric and hepatogastric trunk type, hepatic artery variations and coeliac axis stenosis with collateral mesenteric circulation. Conclusions: Rare variations of the coeliac trunk should always be anticipated before radiological and surgical interventions. Knowledge of unusual coeliac trunk anatomy is important in hepatopancreatobiliary surgery, transplantology, and interventional radiology
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