The Seiberg-Witten Map for Noncommutative Gauge Theories

The Seiberg-Witten map for noncommutative Yang-Mills theories is studied and methods for its explicit construction are discussed which are valid for any gauge group. In particular the use of the evolution equation is described in some detail and its relation to the cohomological approach is elucidated. Cohomological methods which are applicable to gauge theories requiring the Batalin-Vilkoviskii antifield formalism are briefly mentioned. Also, the analogy of the Weyl-Moyal star product with the star product of open bosonic string field theory and possible ramifications of this analogy are briefly mentioned.Comment: 12 pages, talk presented at "Continuous Advances in QCD 2002/Arkadyfest", University of Minnesota, Minneapolis, May 17-23, 2002. A few misprints correcte

Higher order corrections of the extended Chaplygin gas cosmology with varying GG and Λ\Lambda

In this paper, we study two different models of dark energy based on Chaplygin gas equation of state. The first model is the variable modified Chaplygin gas while the second one is the extended Chaplygin gas. Both models are considered in the framework of higher order $f(R)$ modified gravity. We also consider the case of time varying gravitational constant $G$ and $\Lambda$ for both models. We investigate some cosmological parameters such as the Hubble, the deceleration and the equation of state parameters. Then we showed that the model that we considered, extended Chaplygin gas with time-dependent $G$ and $\Lambda$, is consistent with the observational data. Finally we conclude with the discussion of cosmological perturbations of our model.Comment: Perturbation analysis added, typos corrected, references adde

Expression Profile of Multidrug Resistance Efflux Pumps During Intracellular Life of Adherent-Invasive Escherichia coli Strain LF82

Efflux pumps (EPs) are present in all living cells and represent a large and important group of transmembrane proteins involved in transport processes. In bacteria, multidrug resistance efflux pumps (MDR EPs) confer resistance to antibiotics at different levels and are deeply implicated in the fast and dramatic emergence of antibiotic resistance. Recently, several reports have outlined the great versatility of MDR EPs in exporting a large variety of compounds other than antibiotics, thus promoting bacterial adaptation to a wide range of habitats. In several bacterial pathogens, MDR EPs contribute to increase the virulence potential and are directly involved in the crosstalk with host cells. In this work, we have investigated the possible role of MDR EPs in the infectious process of the adherent-invasive Escherichia coli (AIEC), a group of pathogenic E. coli that colonize the ileal mucosa of Crohn disease (CD) patients causing a strong intestinal inflammation. The results we have obtained indicate that, with the exception of mdtM, all MDR-EPs encoding genes present in E.coli K12 are conserved in the AIEC prototype strain LF82. The analysis of MDR EP expression during LF82 infection of macrophages and epithelial cells reveals that their transcription is highly modulated during the bacterial intracellular life. Notably, some EP genes are regulated in a cell-type specific manner, strongly suggesting that their function is required for LF82 successful infection. AIEC are able to adhere to and invade intestinal epithelial cells and, importantly, to survive and multiply within macrophages. Thus, we further investigated the role of EPs specifically induced by macrophage environment. We present evidence indicating that deletion of mdtEF genes, encoding an MDR EP belonging to the resistance nodulation division (RND) family, significantly impairs survival of LF82 in macrophages and that the wild type phenotype can be restored by trans-complementation with functional MdtEF pump. Altogether, our results indicate a strong involvement of MDR EPs in host pathogen interaction also in AIEC and highlight the contribution of MdtEF to the fitness of LF82 in the macrophage environment

A Cohomological Approach to the Non-Abelian Seiberg-Witten Map

We present a cohomological method for obtaining the non-Abelian Seiberg-Witten map for any gauge group and to any order in theta. By introducing a ghost field, we are able to express the equations defining the Seiberg-Witten map through a coboundary operator, so that they can be solved by constructing a corresponding homotopy operator.Comment: 18 pages. References added and some misprints correcte

AcrAB efflux pump impacts on the survival of adherent-invasive Escherichia coli strain LF82 inside macrophages

The tripartite complex AcrAB-TolC is the major RND pump in Escherichia coli and other Enterobacteriaceae. It consists of the AcrB transporter, which is embedded in the inner membrane, the AcrA adapter located in the periplasm, and the channel protein TolC responsible for the transport of substrates towards the extracellular environment. Besides conferring resistance to many classes of antibiotics, AcrAB plays a role in the pathogenesis and virulence of several bacterial pathogens. Here we report that the AcrAB pump heavily affects the infection process of the LF82 strain, the prototype of Adherent-Invasive Escherichia coli (AIEC) which are highly abundant in the ileal mucosa of Chron disease patients. We found that the deletion of genes encoding AcrA and/or AcrB leads to decreased survival of LF82 within macrophages. Ectopic AcrAB expression in a acrAB defective mutant restores the wild type condition. Furthermore, we demonstrate that inhibition of AcrB and replacement of the transporter with an unfunctional AcrB also interfere with bacterial viability inside macrophages. Overall, these data suggest a pivotal role of the AcrAB efflux pump in bacteria-host cell interactions also in AIEC

Cosmic evolution of the logarithmic f(R) model and the dS swampland conjecture

In this paper, we study the inflationary scenario in logarithmic f(R) gravity, where the rate of inflation roll is constant. On the other hand, our gravitational f(R) model is a polynomial plus a logarithmic term. We take advantage of constant-roll conditions and investigate the cosmic evolution of the logarithmic f(R) gravity. Therefore, we plot some figures such as the scalar spectrum index $n_{s}$ and tensor-to-scaler ratio $r$ concerning $n$, $\beta$ and model's constant parameters, i.e., $\alpha$, $\theta$ and $\gamma$ respectively. Also, we obtain the potential by using the constant roll condition. We know that the potential value obtained with this condition has an exact value. Next, we challenge it with refined swampland conjecture with respect to the Planck data. Finally, we compare our results with the experimental data, especially Planck 2018.Comment: 20pages, 5 figure

Outcomes after open and endovascular repair of non-ruptured true pancreaticoduodenal and gastroduodenal artery aneurysms associated with coeliac artery compression. A multicentre retrospective study

Objective: True aneurysms of the peri-pancreatic arcade (PDAA) have been attributed to increased collateral flow related to coeliac axis (CA) occlusion by a median arcuate ligament (MAL). Although PDAA exclusion is currently recommended, simultaneous CA release and the technique to be used are debated. The aim of this retrospective multicentre study was to compare the results of open surgical repair of true non-ruptured PDAA with release or CA bypass (group A) vs. coil embolisation of PDAA and CA stenting or laparoscopic release (group B). Methods: From January 1994 to February 2019, 57 consecutive patients (group A: 31 patients; group B: 26 patients), including 35 (61%) men (mean age 56 ± 11 years), were treated at three centres. Twenty-six patients (46%) presented with non-specific abdominal pain: 15 (48%) in group A and 11 (42%) in group B (p = .80). Results: No patient died during the post-operative period. At 30 days, all PDAAs following open repair and embolisation had been treated successfully. In group A, all CAs treated by MAL release or bypass were patent. In group B, 2/12 CA stentings failed at < 48 hours, and all MAL released by laparoscopy were successful. Median length of hospital stay was significantly greater in group A than in group B (5 vs. 3 days; p = .001). In group A, all PDAAs remained excluded. In group B, three PDAA recanalisations following embolisation were treated successfully (two redo embolisations and one open surgical resection). At six years, Kaplan–Meier estimates of freedom for PDAA recanalisation were 100% in group A, and 88% ± 6% in group B (p = .082). No PDAA ruptured during follow up. In group A, all 37 CAs treated by MAL release were patent, and one aortohepatic bypass occluded. In group B, five CAs occluded: four after stenting and the other after laparoscopic MAL release with two redo stenting and three aortohepatic bypasses. Estimates of freedom from CA restenosis/occlusion were 95% ± 3% for MAL release or visceral bypass, and 60% ± 9% for CA stenting (p = .001). Two late restenoses following CA stenting were associated with PDAA recanalisation. Conclusion: Current data suggest that open and endovascular treatment of PDAA can be performed with excellent post-operative results in both groups. However, PDAA embolisation was associated with few midterm recanalisations and CA stenting with a significant number of early and midterm failures

Cellular localisation of the anti-cancer drug camptothecin in Camptotheca acuminata Decne (Nyssaceae)

In Camptotheca acuminata, we studied the cellular sites of accumulation of the alkaloid camptothecin (CPT), in both plants grown in the field and those grown in a greenhouse, subjecting the latter to stress (i.e., draught, nutritional deficit, and pruning). Fresh sections of the leaf, stem, and root were analysed for the presence of CPT by examining the autofluorescence that the CPT molecule emits when exposed to UV radiation. In the plants grown in the field, CPT was observed only rarely. In the greenhouse plants, CPT had accumulated in crystalline form in the vacuole of specialised cells (i.e., segregator idioblasts), which were not morphologically distinguishable from the cells of the surrounding tissues. In the organs examined, the segregator idioblasts were localised in parenchymatic and epidermal tissues. CPT crystals were also detected in the glandular trichomes on both the stem and leaf

Accumulation of essential oils in relation to root differentiation in Angelica archangelica L.

The accumulation of essential oils in Angelica archangelica subsp. archangelica roots at different developmental stages was investigated through histochemical and chemical analyses. Roots less than 1 mm in diameter showed a primary diarch structure and two primary secretory ducts in the pericycle. These ducts were ephemeral and probably became dysfunctional early on. Oil accumulation was observed only in the secondary secretory ducts formed by cambium activity and located in the secondary phloem. Gas chromatographic analyses revealed that only taproots exceeding 5 mm in diameter contained a high concentration of a- and b- phellandrene, which appreciably influence the oil's aroma