2,368 research outputs found
Pasta-making properties of the new durum wheat variety biensur suitable for the northern mediterranean environment
Industrial pasta is commonly made from mixtures of semolina from different durum wheat varieties, and there is a very low market presence of mono-varietal pasta from local, short supply chains. In this work, dough rheological properties and pasta quality traits of the new durum wheat cv. Biensur, which has a high HMW/LMW-GS ratio, were evaluated with a view to developing short-chain, mono-varietal pasta production in NE Italy. Chemical and sensory analyses on short-cut pasta, viz. tubetti, made with semolina from cv. Biensur at two drying temperatures revealed that it has good technological characteristics and stability, excellent cooking and sensory properties, and is comparable to the high-quality commercial reference cv. Aureo. We conclude that Biensur provides farmers and traders with new market opportunities and offers improvements to the environmental and economic sustainability of the durum wheat chain
Optimization of Short Coherent Control Pulses
The coherent control of small quantum system is considered. For a two-level
system coupled to an arbitrary bath we consider a pulse of finite duration. We
derive the leading and the next-leading order corrections to the evolution
operator due to the non-commutation of the pulse and the bath Hamiltonian. The
conditions are computed that make the leading corrections vanish. The pulse
shapes optimized in this way are given for and pulses.Comment: 9 pages, 6 figures; published versio
Wikipedia Entities as <i>Rendezvous</i> across Languages: Grounding Multilingual Language Models by Predicting Wikipedia Hyperlinks
REPRESENTING WITH LIGHT. VIDEO PROJECTION MAPPING FOR CULTURAL HERITAGE
In this paper, we describe a cross-disciplinary process that uses photogrammetric surveys as a precise basis for video projection mapping techniques. Beginning with a solid basis that uses geoinformatics technologies, such as laser scanning and photogrammetric survey, the method sets, as a first step, the physical and geometrical acquisition of the object. Precision and accuracy are the basics that allow the analysis of the artwork, both at a small or large scale, to evaluate details and correspondences. Testing contents at different scales of the object, using 3D printed replicas or real architectures is the second step of the investigation.The core of the process is the use of equations of collinearity into an interactive system such as Max&thinsp;7, a visual programming language for music and multimedia, in order to facilitate operators to have a fast image correction, directly inside the interactive software. Interactivity gives also the opportunity to easily configure a set of actions to let the spectators to directly change and control the animation content. The paper goes through the different phases of the research, analysing the results and the progress through a series of events on real architecture and experiments on 3d printed models to test the level of involvement of the audience and the flexibility of the system in terms of content.The idea of using the collinearity equation inside da software Max&thinsp;7 was developed for the M.Arch final Thesis by Massimo Visonà and Tommaso Pasini of the University of Venice (IUAV) in collaboration with the Digital Exhibit Postgraduate Master Course (MDE Iuav)
K-ATP channel gene expression is induced by urocortin and mediates its cardioprotective effect
Background-Urocortin is a novel cardioprotective agent that can protect cardiac myocytes from the damaging effects of ischemia/reperfusion both in culture and in the intact heart and is effective when given at reperfusion.Methods and Results-We have analyzed global changes in gone expression in cardiac myocytes after urocortin treatment using gene chip technology. We report that urocortin specifically induces enhanced expression of the Kir 6.1 cardiac potassium channel subunit. On the basis of this finding, we showed that the cardioprotective effect of urocortin both in isolated cardiac cells and in the intact heart is specifically blocked by both generalized and mitochondrial-specific K-ATP channel blockers, whereas the cardioprotective effect of cardiotrophin-1 is unaffected. Conversely, inhibiting the Kir 6.1 channel subunit greatly enhances cardiac cell death after ischemia.Conclusions-This is, to our knowledge, the first report of the altered expression of a K-ATP. channel subunit induced by a cardioprotective agent and demonstrates that K-ATP, channel opening is essential for the effect of this novel cardioprotective agent
Spectral perturbation by rank- matrices
Let and designate matrices with coefficients in a field
. In this paper, we completely answer the following question: For fixed,
what are the possible characteristic polynomials of , where ranges
over matrices of rank ?Comment: Comments are welcom
TrkA is amplified in malignant melanoma patients and induces an anti-proliferative response in cell lines.
Background: The nerve growth factor (NGF) receptor tyrosine-kinase TrkA is a well-known determinant of the melanocytic lineage, through modulation of the MAPK and AKT cascades. While TrkA gene is frequently rearranged in cancers, its involvement in malignant melanoma (MM) development is still unclear.
Methods: We analyzed a dataset of primary cutaneous MM (n = 31) by array comparative genomic hybridization (aCGH), to identify genomic amplifications associated with tumor progression. The analysis was validated by genomic quantitative PCR (qPCR) on an extended set of cases (n = 64) and the results were correlated with the clinical outcome. To investigate TrkA molecular pathways and cellular function, we generated inducible activation of the NGF-TrkA signaling in human MM cell lines.
Results: We identified amplification of 1q23.1, where the TrkA locus resides, as a candidate hotspot implicated in the progression of MM. Across 40 amplicons detected, segmental amplification of 1q23.1 showed the strongest association with tumor thickness. By validation of the analysis, TrkA gene amplification emerged as a frequent event in primary melanomas (50 % of patients), and correlated with worse clinical outcome. However, experiments in cell lines revealed that induction of the NGF-TrkA signaling produced a phenotype of dramatic suppression of cell proliferation through inhibition of cell division and pronounced intracellular vacuolization, in a way straightly dependent on NGF activation of TrkA. These events were triggered via MAPK activity but not via AKT, and involved p21(cip1) protein increase, compatibly with a mechanism of oncogene-induced growth arrest.
Conclusions: Taken together, our findings point to TrkA as a candidate oncogene in MM and support a model in which the NGF-TrkA-MAPK pathway may mediate a trade-off between neoplastic transformation and adaptive anti-proliferative response
Populações de minhocas amostradas usando diferentes métodos de coleta (elétrico, químico e manual) em ecossistemas da região de Londrina, Paraná.
Radio galaxies in galaxy groups: Kinematics, scaling relations, and AGN feedback
We investigate the kinematic properties of a large (N = 998) sample of COSMOS spectroscopic galaxy members distributed among 79 groups. We identify the Brightest Group Galaxies (BGGs) and cross-match our data with the VLA-COSMOS Deep survey at 1.4 GHz, classifying our parent sample into radio/non-radio BGGs and radio/non-radio satellites. The radio luminosity distribution spans from W Hz to W Hz. A phase-space analysis, performed by comparing the velocity ratio (line-of-sight velocity divided by the group velocity dispersion) with the galaxy-group centre offset, reveals that BGGs (radio and non-radio) are mostly (80 per cent) ancient infallers. Furthermore, the strongest ( W Hz) radio galaxies are always found within 0.2 from the group centre. Comparing our samples with HORIZON-AGN, we find that the velocities and offsets of simulated galaxies are more similar to radio BGGs than to non-radio BGGs, albeit statistical tests still highlight significant differences between simulated and real objects. We find that radio BGGs are more likely to be hosted in high-mass groups. Finally, we observe correlations between the powers of BGG radio galaxies and the X-ray temperatures, , and X-ray luminosities, , of the host groups. This supports the existence of a link between the intragroup medium and the central radio source. The occurrence of powerful radio galaxies at group centres can be explained by Chaotic Cold Accretion, as the AGN can feed from both the galactic and intragroup condensation, leading to the observed positive correlation
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