Compendio de la historia de la Virgen Nª Señora de la Cueva Santa, con su novena [Texto impreso] : enmendado, y añadido en esta tercera impression con... noticias de la Historia que escrivió... Pasqual Agramunt, de la Compañia de Jesus

Sign. : A-H8, I4Marca tip. en port.La h. de grab. xil. representa a N.S. de la Cueva Santa

Desagrauios de Christo nuestro bien Sacramentado, en satisfacion de las ofensas, que contra su Magestad se cometen... : tomo segundo, contiene dos tratados...

BHR/A-007-361(BIB LVL) w-FONDO ANTIGUO(ES-GrU)b13643964-34cbua_ugr(OCoLC)934086407UGRAOPPascual, Miguel Ángel (s.I.)Desagrauios de Christo nuestro bien Sacramentado, en satisfacion de las ofensas, que contra su Magestad se cometen...[En Valencia[4], 224, 104, [24] p., [2] en bl.Lugar, impresor y fecha de imp. tomados del tomo primeroPort. orladaTexto a dos col.Apostillas marginale

Desagrauios de Christo nuestro bien Sacramentado, en satisfacion de las ofensas, que contra su Magestad se cometen... tomo primero ; ponese al principio un Epilogo de la vida, y heroycas virtudes del ... Señor D. Iuan Bautista Ivañez, Obispo electo de Origuela...

BHR/A-007-360(BIB LVL) w-FONDO ANTIGUO(ES-GrU)b13643927-34cbua_ugr(OCoLC)934086377UGRAOPPascual, Miguel Ángel (S.I.)Desagrauios de Christo nuestro bien Sacramentado, en satisfacion de las ofensas, que contra su Magestad se cometen...En Valencia[24], 36 [i.e. 38], 144 p., [2] en bl.Port. orladaError de pag. en la segunda secuencia, 36 por 38Texto a dos col.Apostillas marginalesEpilogo de la vida, y heroycas virtudes del ... Señor Don Iuan Bautista Ivañez..., p. 1-[38

Sermones de la Seráfica fundadora Sta. Teresa de Jesus

Sign.: a-c4, A-Z4, 2A-2Z4, 3A-3E4, 3F2, [calderón]-3[calderón]4, 4[calderón]2.Texto a dos col

Proclamacion del Rey Ntro. Sor. Dn. Carlos III ... en su fidelissima ciudad de Valencia

Martí Grajales atribuye la obra al P. Raimundo AlafontSign.: [], a-b4, A-H4, I2Anteport. y Port. con grab. calc. de: "Hipp. Ricarte inv del et sc"Grabado calc. de: "Francisc.s Bru Inv et del., Emanuel Bru sculp Vala. Año 1759" en verso sign. a1 y verso sign. A1Las 5 láminas grabadas por: Pascual Moles, Pascual Cucó, Carlos Francia e Hipólito Ricart

X chromosome inactivation does not necessarily determine the severity of the phenotype in Rett syndrome patients

Rett syndrome (RTT) is a severe neurological disorder usually caused by mutations in the MECP2 gene. Since the MECP2 gene is located on the X chromosome, X chromosome inactivation (XCI) could play a role in the wide range of phenotypic variation of RTT patients; however, classical methylation-based protocols to evaluate XCI could not determine whether the preferentially inactivated X chromosome carried the mutant or the wild-type allele. Therefore, we developed an allele-specific methylation-based assay to evaluate methylation at the loci of several recurrent MECP2 mutations. We analyzed the XCI patterns in the blood of 174 RTT patients, but we did not find a clear correlation between XCI and the clinical presentation. We also compared XCI in blood and brain cortex samples of two patients and found differences between XCI patterns in these tissues. However, RTT mainly being a neurological disease complicates the establishment of a correlation between the XCI in blood and the clinical presentation of the patients. Furthermore, we analyzed MECP2 transcript levels and found differences from the expected levels according to XCI. Many factors other than XCI could affect the RTT phenotype, which in combination could influence the clinical presentation of RTT patients to a greater extent than slight variations in the XCI pattern

The burden of unintentional drowning: Global, regional and national estimates of mortality from the Global Burden of Disease 2017 Study

__Background:__ Drowning is a leading cause of injury-related mortality globally. Unintentional drowning (International Classification of Diseases (ICD) 10 codes W65-74 and ICD9 E910) is one of the 30 mutually exclusive and collectively exhaustive causes of injury-related mortality in the Global Burden of Disease (GBD) study. This study's objective is to describe unintentional drowning using GBD estimates from 1990 to 2017. __Methods:__ Unintentional drowning from GBD 2017 was estimated for cause-specific mortality and years of life lost (YLLs), age, sex, country, region, Socio-demographic Index (SDI) quintile, and trends from 1990 to 2017. GBD 2017 used standard GBD methods for estimating mortality from drowning. __Results:__ Globally, unintentional drowning mortality decreased by 44.5% between 1990 and 2017, from 531 956 (uncertainty interval (UI): 484 107 to 572 854) to 295 210 (284 493 to 306 187) deaths. Global age-standardised mortality rates decreased 57.4%, from 9.3 (8.5 to 10.0) in 1990 to 4.0 (3.8 to 4.1) per 100 000 per annum in 2017. Unintentional drowning-associated mortality was generally higher in children, males and in low-SDI to middle-SDI countries. China, India, Pakistan and Bangladesh accounted for 51.2% of all drowning deaths in 2017. Oceania was the region with the highest rate of age-standardised YLLs in 2017, with 45 434 (40 850 to 50 539) YLLs per 100 000 across both sexes. __Conclusions:__ There has been a decline in global drowning rates. This study shows that the decline was not consistent across countries. The results reinforce the need for continued and improved policy, prevention and research efforts, with a focus on low-and middle-income countries

Global maps of soil temperature.

Research in global change ecology relies heavily on global climatic grids derived from estimates of air temperature in open areas at around 2 m above the ground. These climatic grids do not reflect conditions below vegetation canopies and near the ground surface, where critical ecosystem functions occur and most terrestrial species reside. Here, we provide global maps of soil temperature and bioclimatic variables at a 1-km <sup>2</sup> resolution for 0-5 and 5-15 cm soil depth. These maps were created by calculating the difference (i.e. offset) between in situ soil temperature measurements, based on time series from over 1200 1-km <sup>2</sup> pixels (summarized from 8519 unique temperature sensors) across all the world's major terrestrial biomes, and coarse-grained air temperature estimates from ERA5-Land (an atmospheric reanalysis by the European Centre for Medium-Range Weather Forecasts). We show that mean annual soil temperature differs markedly from the corresponding gridded air temperature, by up to 10°C (mean = 3.0 ± 2.1°C), with substantial variation across biomes and seasons. Over the year, soils in cold and/or dry biomes are substantially warmer (+3.6 ± 2.3°C) than gridded air temperature, whereas soils in warm and humid environments are on average slightly cooler (-0.7 ± 2.3°C). The observed substantial and biome-specific offsets emphasize that the projected impacts of climate and climate change on near-surface biodiversity and ecosystem functioning are inaccurately assessed when air rather than soil temperature is used, especially in cold environments. The global soil-related bioclimatic variables provided here are an important step forward for any application in ecology and related disciplines. Nevertheless, we highlight the need to fill remaining geographic gaps by collecting more in situ measurements of microclimate conditions to further enhance the spatiotemporal resolution of global soil temperature products for ecological applications

Search for the Zγ decay mode of new high-mass resonances in pp collisions at √s = 13 TeV with the ATLAS detector

This letter presents a search for narrow, high-mass resonances in the Zγ final state with the Z boson decaying into a pair of electrons or muons. The √s = 13 TeV pp collision data were recorded by the ATLAS detector at the CERN Large Hadron Collider and have an integrated luminosity of 140 fb−1. The data are found to be in agreement with the Standard Model background expectation. Upper limits are set on the resonance production cross section times the decay branching ratio into Zγ. For spin-0 resonances produced via gluon–gluon fusion, the observed limits at 95% confidence level vary between 65.5 fb and 0.6 fb, while for spin-2 resonances produced via gluon–gluon fusion (or quark–antiquark initial states) limits vary between 77.4 (76.1) fb and 0.6 (0.5) fb, for the mass range from 220 GeV to 3400 GeV

The ATLAS trigger system for LHC Run 3 and trigger performance in 2022

The ATLAS trigger system is a crucial component of the ATLAS experiment at the LHC. It is responsible for selecting events in line with the ATLAS physics programme. This paper presents an overview of the changes to the trigger and data acquisition system during the second long shutdown of the LHC, and shows the performance of the trigger system and its components in the proton-proton collisions during the 2022 commissioning period as well as its expected performance in proton-proton and heavy-ion collisions for the remainder of the third LHC data-taking period (2022–2025)