Entre les vivants et les morts, les pompes funèbres aux portes du marché

Article repris dans Problèmes économiques, n°2.695, janvier 2001, Paris, La Documentation Française et dans « Echo des recherches », Sciences Humaines, avril 2001.National audienceIn the 1970s, a funeral market emerged in France as the communal monopolies dating from a 1904 law were eroded. Studying this emerging marketplace sheds light on a merchandising process in this branch of the economy. This process has unfolded against the backdrop of a change in geography (the places where people die) and a change in the symbolic relation to death. It has entailed: designing funeral services in place of rituals; reworking the ‘mediations' that institute economic transactions between market segments of living clients, on the one hand, and, on the other, businesses of different sizes that provide various products and services; working out new arrangements for winning clients (products, services, package deals, etc.); and developing new business qualifications. Deeply anchored in the realm of symbols, the funeral business must handle two anthropological aspects of exchanges (the market and symbolic ones) that are structurally antagonistic but that its economic organisation cannot abolish. This inquiry focuses on how symbolic issues limit the activities of these businesses, in particular by forcing them to reconcile competition over prices (the very basis of the marketing dimension) and discretion about prices (itself required by the symbolic prohibition against reducing clients to mere customers.)En étudiant la création d'un marché des pompes funèbres1 en France, né de la suppression des monopoles communaux, les auteurs nous donnent à voir un processus de marchandisation : construction d'une prestation en lieu et place des rituels, recomposition des médiations qui instituent l'échange économique, construction de nouveaux dispositifs et compétences d'échange. Profondément ancré dans la sphère du symbolique, le secteur doit cependant conjuguer deux registres anthropologiques de l'échange, marchand et symbolique, structurellement antagonistes, que ne peut abolir son organisation économique. Les auteurs s'interrogent sur la façon dont l'enjeu symbolique conditionne l'activité des acteurs économique

QTL detection for a medium density SNP panel: comparison of different LD and LA methods

Background: New molecular technologies allow high throughput genotyping for QTL mapping with dense genetic maps. Therefore, the interest of linkage analysis models against linkage disequilibrium could be questioned. As these two strategies are very sensitive to marker density, experimental design structures, linkage disequilibrium extent and QTL effect, we propose to investigate these parameters effects on QTL detection.[br/] Methods: The XIIIth QTLMAS workshop simulated dataset was analysed using three linkage disequilibrium models and a linkage analysis model. Interval mapping, multivariate and interaction between QTL analyses were performed using QTLMAP.[br/] Results: The linkage analysis models identified 13 QTL, from which 10 mapped close of the 18 which were simulated and three other positions being falsely mapped as containing a QTL. Most of the QTLs identified by interval mapping analysis are not clearly detected by any linkage disequilibrium model. In addition, QTL effects are evolving during the time which was not observed using the linkage disequilibrium models.[br/] Conclusions: Our results show that for such a marker density the interval mapping strategy is still better than using the linkage disequilibrium only. While the experimental design structure gives a lot of power to both approaches, the marker density and informativity clearly affect linkage disequilibrium efficiency for QTL detection

Interaction efficace entre les réseaux rapides et le stockage distribué dans les grappes de calcul

National audienceLes applications parallèles s'exécutant sur les grappes nécessitent à la fois des communications performantes entre les différents noeuds et des accès efficaces au système de stockage. Nous proposons dans ce travail d'améliorer les performances du stockage distribué dans les grappes en utilisant au mieux le réseau haute performance sous-jacent. Nous montrons que les besoins du stockage sont très différents de ceux du calcul parallèle et proposons différentes solutions pour résoudre, les problèmes liés au contrôle du réseau mais montrons qu'il est nécessaire de modifier l'interface de programmation réseau et le système d'explotation pour venir à bout des difficultés liées au transfert de données. Des expérimentations montrent qu'elles permettent une utilisation aisée et efficace des réseaux rapides dans le cadre du stockage distribué

Quantum dot-cavity strong-coupling regime measured through coherent reflection spectroscopy in a very high-Q micropillar

We report on the coherent reflection spectroscopy of a high-quality factor micropillar, in the strong coupling regime with a single InGaAs annealed quantum dot. The absolute reflectivity measurement is used to study the characteristics of our device at low and high excitation power. The strong coupling is obtained with a g=16 \mueV coupling strength in a 7.3\mum diameter micropillar, with a cavity spectral width kappa=20.5 \mueV (Q=65 000). The factor of merit of the strong-coupling regime, 4g/kappa=3, is the current state-of-the-art for a quantum dot-micropillar system

Comparison of analyses of the XVth QTLMAS common dataset III: Genomic Estimations of Breeding Values

<p>Abstract</p> <p>Background</p> <p>The QTLMAS XV^thdataset consisted of pedigree, marker genotypes and quantitative trait performances of animals with a sib family structure. Pedigree and genotypes concerned 3,000 progenies among those 2,000 were phenotyped. The trait was regulated by 8 QTLs which displayed additive, imprinting or epistatic effects. The 1,000 unphenotyped progenies were considered as candidates to selection and their Genomic Estimated Breeding Values (GEBV) were evaluated by participants of the XV^thQTLMAS workshop. This paper aims at comparing the GEBV estimation results obtained by seven participants to the workshop.</p> <p>Methods</p> <p>From the known QTL genotypes of each candidate, two "true" genomic values (TV) were estimated by organizers: the genotypic value of the candidate (TGV) and the expectation of its progeny genotypic values (TBV). GEBV were computed by the participants following different statistical methods: random linear models (including BLUP and Ridge Regression), selection variable techniques (LASSO, Elastic Net) and Bayesian methods. Accuracy was evaluated by the correlation between TV (TGV or TBV) and GEBV presented by participants. Rank correlation of the best 10% of individuals and error in predictions were also evaluated. Bias was tested by regression of TV on GEBV.</p> <p>Results</p> <p>Large differences between methods were found for all criteria and type of genetic values (TGV, TBV). In general, the criteria ranked consistently methods belonging to the same family.</p> <p>Conclusions</p> <p>Bayesian methods - A<B<C<Cπ - were the most efficient whatever the criteria and the True Value considered (with the notable exception of the MSEP of the TBV). The selection variable procedures (LASSO, Elastic Net and some adaptations) performed similarly, probably at a much lower computing cost. The TABLUP, which combines BayesB and GBLUP, generally did well. The simplest methods, GBLUP or Ridge Regression, and even worst, the fixed linear model, were much less efficient.</p

An Efficient Network API for in-Kernel Applications in Clusters

International audienceRunning parallel applications on clusters with high-speed local networks requires fast communication between computing nodes but also low latency and high bandwidth file access. However, the application programming interfaces of high-speed local networks were designed for MPI communication and do not always meet the requirements of other applications like distributed file systems. In this paper, we explore several solutions to improve the use of high-speed network for in-kernel applications. Distributed file systems implemented on top of the GM interface of Myrinet are first examined to demonstrate how hard it is to get an efficient interaction between such applications and the network. Then, we propose solutions to simplify and improve this interaction and integrate them into the kernel interface of the new Myrinet. Performance comparisons between MX and GM, and their usage in both a distributed file system and a zero-copy protocol show nice improvements. Moreover, we are able to improve the performance of the flexible kernel API we designed in MX that allows to remove some intermediate copy

A microarray configuration to quantify expression levels and relative abundance of splice variants

Over the past decade, alternative RNA splicing has raised a great interest appearing to be of high importance in the generation of expression diversity. This regulatory process plays a critical role in the normal development and its impact on the initiation and development of human disorders as well as on the pharmacological properties of drugs is increasingly being recognized. Only few studies describe specific alternative splicing expression profiling. Microarray strategies have been conceived to address alternative splicing events but with very few experimental data related to their abilities to provide true quantification values. We have developed a specific microarray configuration relying on a few, well optimized probes per splice event. Basically, five probes of 24mer are used to fully characterize a splice event. These probes are of two types, exon probes and junction probes, and are either specific to a splice event or not. The performances of such a ‘splice array’ were validated on synthetic model systems and on complex biological materials. The results indicate that DNA chips based on this design combining exon and junction derived probes enable the detection and, absolute and relative quantification of splice variants. In addition, this strategy is compatible with all the microarrays that use oligonucleotide probes

Epitaxial graphene prepared by chemical vapor deposition on single crystal thin iridium films on sapphire

Uniform single layer graphene was grown on single-crystal Ir films a few nanometers thick which were prepared by pulsed laser deposition on sapphire wafers. These graphene layers have a single crystallographic orientation and a very low density of defects, as shown by diffraction, scanning tunnelling microscopy, and Raman spectroscopy. Their structural quality is as high as that of graphene produced on Ir bulk single crystals, i.e. much higher than on metal thin films used so far.Comment: To appear in Appl. Phys. Let