1,778 research outputs found

    The crustal nature of the Chukchi Cap and the Lord Howe Rise

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    An In Depth Study into Using EMI Signatures for Appliance Identification

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    Energy conservation is a key factor towards long term energy sustainability. Real-time end user energy feedback, using disaggregated electric load composition, can play a pivotal role in motivating consumers towards energy conservation. Recent works have explored using high frequency conducted electromagnetic interference (EMI) on power lines as a single point sensing parameter for monitoring common home appliances. However, key questions regarding the reliability and feasibility of using EMI signatures for non-intrusive load monitoring over multiple appliances across different sensing paradigms remain unanswered. This work presents some of the key challenges towards using EMI as a unique and time invariant feature for load disaggregation. In-depth empirical evaluations of a large number of appliances in different sensing configurations are carried out, in both laboratory and real world settings. Insights into the effects of external parameters such as line impedance, background noise and appliance coupling on the EMI behavior of an appliance are realized through simulations and measurements. A generic approach for simulating the EMI behavior of an appliance that can then be used to do a detailed analysis of real world phenomenology is presented. The simulation approach is validated with EMI data from a router. Our EMI dataset - High Frequency EMI Dataset (HFED) is also released

    Patterns of Dispersion, Movement and Feeding of the Sea Urchin Lytechinus variegatus, and the Potential Implications for Grazing Impact on Live Seagrass

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    The sea urchin Lytechinus variegatus is a known grazer of both living and dead tissue of turtlegrass, Thalassia testudinum, occasionally denuding large areas of seagrass. Field studies have attempted to assess effects of herbivory on seagrass by enclosing urchins at various densities. However, it is unclear how unrestricted urchins affect seagrass at lower densities more typically observed in the field. This study describes movement, feeding, and distribution of L. variegatus within beds of T. testudinum in St. Joseph Bay, Florida (USA) to quantify this urchin’s impact as a seagrass grazer. Urchins were absent from portions of seagrass beds closest to shore, present at low densities midway across the bed, and at highest densities (up to ~5 individuals/m2) at the offshore edge of the bed. Urchins tended not to aggregate, moved twice as rapidly where seagrass cover was reduced, and moved \u3e 20X faster when placed in areas of open sand. Dead seagrass tissue occurred 4—30X more frequently on oral surfaces than living seagrass tissue. Fecal pellets with dead seagrass tissue were \u3e 3X more common than pellets with live seagrass tissue. Injury to seagrass leaves was more common along dead leaf sections than live sections (\u3e 2—10X). Overall, spatial distributions, movement, and diet indicate that L. variegatus at densities observed in this study would tend to have minimal effects on living seagrass. Episodic periods of denuding grassbeds reported in the literature suggest L. variegatus switches to live seagrass tissue as dead tissue becomes scarce during times of high urchin density

    Role of tyrosine M210 in the initial charge separation of reaction centers of Rhodobacter sphaeroides

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    Femtosecond spectroscopy was used in combination with site-directed mutagenesis to study the influence of tyrosine M210 (YM210) on the primary electron transfer in the reaction center of Rhodobacter sphaeroides. The exchange of YM210 to phenylalanine caused the time constant of primary electron transfer to increase from 3.5 f 0.4 ps to 16 f 6 ps while the exchange to leucine increased the time constant even more to 22 f 8 ps. The results suggest that tyrosine M210 is important for the fast rate of the primary electron transfer

    Survival Motor Neuron (SMN) protein is required for normal mouse liver development

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    Spinal Muscular Atrophy (SMA) is caused by mutation or deletion of the survival motor neuron 1 (SMN1) gene. Decreased levels of, cell-ubiquitous, SMN protein is associated with a range of systemic pathologies reported in severe patients. Despite high levels of SMN protein in normal liver, there is no comprehensive study of liver pathology in SMA. We describe failed liver development in response to reduced SMN levels, in a mouse model of severe SMA. The SMA liver is dark red, small and has: iron deposition; immature sinusoids congested with blood; persistent erythropoietic elements and increased immature red blood cells; increased and persistent megakaryocytes which release high levels of platelets found as clot-like accumulations in the heart. Myelopoiesis in contrast, was unaffected. Further analysis revealed significant molecular changes in SMA liver, consistent with the morphological findings. Antisense treatment from birth with PMO25, increased lifespan and ameliorated all morphological defects in liver by postnatal day 21. Defects in the liver are evident at birth, prior to motor system pathology, and impair essential liver function in SMA. Liver is a key recipient of SMA therapies, and systemically delivered antisense treatment, completely rescued liver pathology. Liver therefore, represents an important therapeutic target in SMA

    Widespread tissue hypoxia dysregulates cell and metabolic pathways in SMA

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    Open Access via the Wiley Jisc Agreement Acknowledgments: SHP, EH‐G, INF, SD’A, and JMC were funded by SMA Europe (SMA UK and Prinses Beatrix Spierfonds). Thanks to Prof Andy Welch for helpful discussions on imaging.Peer reviewedPublisher PD

    Numerical modelling of Non-Transform Discontinuity geometry: Implication for ridge structure, volcano-tectonic fabric development and hydrothermal activity at segment ends.

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    Ocean ridge discontinuities partition and offset spreading centres at a range of scales. Large scale discontinuities (10's–100's km) are synonymous with first-order transform faults, which have well defined linear fault zone valleys. In contrast, Non-Transform Discontinuities (NTDs) are diffuse, smaller scale offsets (0 to b20 km), characterised by central basins or topographic highs. The geometry of NTD offsets can be categorised by the sense of offset, either right-stepping or left-stepping, and by the relative positions of the segment tips. The segment tip configurations include under-lapping, over-lapping or simple across-axis jumps or stepping in the ridge axis. In this study finite difference software is used to model segment geometry at a slow-spreading ridge under a normal tensile-stress within a homogeneous and isotropic medium. Along- and across-axis segment separations were varied incrementally for left- and right-stepping senses. The results show that the ratio of along-axis to across-axis segment tip separation is a dominant control of stress field rotation within an NTD. Features which most clearly show rotation within an NTD include basins and tectonically controlled constructional ridges. The obliquity of these features along with measurements of the surrounding fault fabrics are used as a way of observing and determining stress rotations within NTDs along the Central Indian Ridge (CIR). These rotations were used to obtain segment geometries from models where the central tensor showed an equivalentrotation. The results show that geometry has a profound effect on stress field rotation under which large- and small-scale volcanotectonic fabrics form. In addition, a shortfall of the predicted model tip relative to interpreted positions, along with morphology and observation of the ridge fabrics at the terminations to some segments, suggests the existence of a zone, broadly analogous to theprocess zone observed in fracture mechanics, which we call a damage zone. Given the criteria for the promotion of hydrothermal circulation, this damage zone would have a greater potential for hosting hydrothermal activity.<br/
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