Self-reported depression symptoms in haemodialysis patients: Bi-factor structures of two common measures and their association with clinical factors

Copyright © 2018 Elsevier Inc. All rights reserved.Objective: To validate the factor structure of two common self-report depression tools in a large sample of haemodialysis (HD) patients and to examine their demographic and clinical correlates, including urine output, history of depression and transplantation. Methods: Factor structures of the Beck Depression Inventory (BDI-II) and Patient Health Questionnaire (PHQ-9) were evaluated using confirmatory factor analysis (CFA). Data was utilised from the screening phase (n = 709) of a placebo-controlled feasibility randomised control trial (RCT) of sertraline in HD patients with mild to moderate Major Depressive Disorder. Alternative factor models including bi-factor models for the BDI-II and PHQ-9 were evaluated. Coefficient omega and omega-hierarchical were calculated. Results: For both measures, bi-factor measurement models had the overall best fit to the data, with dominant general depression factors. Omega-hierarchical for the general BDI-II and PHQ-9 factors was 0.94 and 0.88 respectively. Both general factors had high reliability (coefficient omega = 0.97 and 0.94 respectively) and explained over 85% of the explained common variance within their respective models. BDI-II and PHQ-9 general depression factors were negatively associated with age and urine output and positively with a history of depression, antidepressant use within the last 3 months and a history of failed transplantation. In adjusted regression models, age, urine output and a history of depression remained significant. Conclusions: These data suggest that both the BDI-II and PHQ-9 are sufficiently unidimensional to warrant the use of a total score. Younger age, lower urine output and a history of depression appear consistent correlates of depression severity among HD patients.Peer reviewedFinal Accepted Versio

Comparison of depression between kidney transplant recipients from live donors with cadavers in hospitals of Mashhad University of Medical Sciences

AbstractBackground & aim:  Kidney transplant surgery may impact various aspects of the life and results in individual and psychological problems. Receiving a kidney from a cadaver donor is associated with beliefs related to death of donor and with recipient’s survival. The aim of this study was to compare the rate of depression in patients receiving kidney from living donors with cadaveric donor kidney transplant ,patients that were referred to nephrology clinics in hospitals of Mashhad University of Medical Sciences in 2010.Materials & methods:  A descriptive – comparative design was used. The sample of the study consisted of 60 patients receiving kidney from living donors and 60 cadaveric kidney transplantation attended to nephrology clinics in hospitals of Mashhad University of Medical Sciences. Data were collected by a demographic questionnaire and Beck depression Inventory. The reliability of this test was evaluated with test-retest and Pearson correlation test was 0. 95. Data were analyzed with SPSS software (version 13).Finding:  Depression scores in living kidney transplantation group were 11. 6±5. 7 , and in the cadaveric group was 16. 4±9. 4. Independent t-test showed a significant difference between two groups scores of depression (P<0. 005).Conclusion:  The results showed a higher depression scores in kidney transplantation from cadaveric donors. Therefore it is recommended that efforts to detect and treat depression be included in the care of transplant patients before and after the surgery..Key words: Kidney transplant, Cadaver, Live donors, Depression REFERENCES Akman B et al (2004) Depression levels before and after renal transplantation. Transplantation Proceedings. 36(1) 111-113 Anvar-Abnavi M, Bazargani Z) 2010(Prevalence of anxiety and depression in Iranian kidney transplant recipients. 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