Action de l'insuline sur le métabolisme du cholestérol et des acides biliaires chez le Hamster (rôle dans l'induction de la lithiase biliaire cholestérolique)

PARIS7-Bibliothèque centrale (751132105) / SudocSudocFranceF

Expression and localization of adiponectin receptors in rat hypothalamus

National audienc

Les CLA peuvent-ils prévenir l'athérogenèse ?

National audienc

Récepteurs AdipoR1 et R2 à l'adiponectine dans les cellules neuronales : mise en évidence et signalisation associée

National audienc

The natural concentration of the conjugated linoleic acid, cis-9, trans-11 in milk-fat can modulate the atherogenic risk in hyperlipidemic hamsters

International audienc

The natural concentration of the conjugated linoleic acid, cis-9,trans-11, in milk fat has antiatherogenic effects in hyperlipidemic hamsters

International audienc

Les CLA peuvent-ils prévenir l’athérogenèse ?

The anti-atherogenic properties of CLA are now illustrated in many animal studies (Rabbit, Mice and Hamster) or cell culture experiments. These properties can be observed while using either the CLA isomeric mixture (cis9,trans11- and trans10,cis12-, 50 :50) or selected CLA isomers (cis9,trans11- or trans10,cis12-). Especially, these fatty acids consistently attenuate the outcome of primary vascular lesions (fatty streaks), or can even induce a regression of pre-established lesions. There is, paradoxically, no clear relationship between this beneficial effect and an improvement of the lipid status in blood (triglycerides, total cholesterol, LDL-cholesterol, HDL-cholesterol) usually considered as a hallmark in the etiology of atherosclerosis. On the other hand, recent data obtained both in vitro and in vivo indicate that part of the beneficial effects of CLA occurs through the modulation of vascular inflammatory and oxidant stress factors (cytokines and cyclooxygenase), as well as from the expression of adhesion molecules (VCAM, ICAM) in the aorta. This regulation involves the interaction of CLA with transcription factors such as PPARs, LXR and NF-kB targeting the gene expression dowstream. In human, clinical trials are no more conclusive than the animal experiments with regards to the contribution of CLA to modulate the lipid status in blood. Nevertheless, some data highlight the pro-atherogenic role of CLA and especially of the trans10,cis12-isomer, as demonstrated by the increase in the various markers of oxidative stress (isoprostanes) and inflammatory status (C-reactive protein). In conclusion, whereas there is compelling evidence that feeding mixed or pure isomers of CLA attenuates atherosclerosis initiation and progression in several experimental models, human studies are less convincing. Nevertheless, clinical trials addressing sufficient risk factors and risk markers together are still lacking to draw a definitive conclusion and to set up obvious recommandations. The use of the sole blood lipids do not seem to be appropriate for such an evaluation

Long-term consequences of maternal high-fat diet on hypothalamic leptin sensitivity and diet-induced obesity in the offspring

National audienc

Long-term consequences of maternal high-fat diet on hypothalamic leptin sensitivity and diet-induced obesity in the offspring

National audienc

SISTEM KEAMANAN RUMAH BERBASIS ANDROID DENGAN RASBERRY Pi

Smart Home is one of the tools that is developed for ease of automation of smart home management from the start of address, security, comfort, savings, through automation with Android. In designing a micro home security system controller using raspberry pi 3 and Android smartphones that can reduce the number of criminal acts of burglary door. This tool consists of an electro magnetic door lock called a solenoid door lock.This solenoid key is placed on the door of the house for security. The design of this home door security system utilizes Raspberyy pi b + as a control device from near and far by utilizing the wifi network and sms gateway to control opening and closing the home door lock that is controlled via an android mobile. Through web bootstrap that will display the results captured by the camera to provide a home situation every time someone enters.This house door security system that has been successfully built and tested with the working principle if there is someone who forces or breaks the house door in a closed condition, the system will activate a warning or alarm by sounding the buzzer¸ because there is an LDR sensor connected to one switch connected to the solenoid key that results, if the key is opened with a security system then the LDR sensor will turn off and there will be no alarm, but if it is forced to break the LDR sensor will activate and read the movement of the door so that the reaction occurs and the buzzer alarm will sound. This security system is a solution to increase the level of home security ¸ besides this sophisticated system is very easy to use and integrated with android smartphone