Un modelo genetico-ambiental para un estudio prospectivo del estado de salud de los ciudadanos italianos en la Argentina Parte 1. Descripción del método y estadísticas generales sobre poblaciones

The project is born from the hypothesis, today quite accredited, that many diseases are the result of the interaction of genetic and environmental factors.From this hypothesis is born the idea of studying through a natural model the different impact that the environment can have on the modification of the natural history of some diseases. The natural model that most easily meets the methodological requirement is that of the emigrated population and established in an environment very different from that of origin. In a quick analysis emerges that the model of the Italians emigrated to Argentina can respond to this pretension: environment and seasons inverted, different food lifestyle, diverse social structure, low rate of return, significant migratory flow between the years 1920 and 1960 which guarantees a sufficiently long environmental exposure perio

Unitarity Triangle Analysis in the Standard Model and Sensitivity to New Physics

By using the most recent determinations of the several theoretical and experimental input parameters, we update the Unitarity Triangle analysis in the Standard Model and discuss the sensitivity to New Physics effects. We investigate the interest of measuring with a better precision the various physical quantities entering the Unitarity Triangle analysis and study in a model independent way whether, despite the undoubted success of the CKM mechanism in the Standard Model, the Unitarity Triangle analysis still allows the presence of New Physics.Comment: Invited talk at the Workshop on the CKM Unitarity Triangle, IPPP Durham, April 2003 (eConf C0304052). 9 pages LaTeX, 15 eps figures. Misprint corrected and references adde

2000 CKM-Triangle Analysis A Critical Review with Updated Experimental Inputs and Theoretical Parameters

Within the Standard Model, a review of the current determination of the sides and angles of the CKM unitarity triangle is presented, using experimental constraints from the measurements of |\epsilon_K|, |V_{ub}/V_{cb}|, \Delta m_d and from the limit on \Delta m_s, available in September 2000. Results from the experimental search for {B}^0_s-\bar{B}^0_s oscillations are introduced in the present analysis using the likelihood. Special attention is devoted to the determination of the theoretical uncertainties. The purpose of the analysis is to infer regions where the parameters of interest lie with given probabilities. The BaBar "95 %, C.L. scanning" method is also commented.Comment: 44 pages (revised version

The automation of the \"Welding Machine\" for the DUs integration in the KM3NeT experiment

This note describes some technical aspects, in particular the control system, of one of the tools used during Process-1 of the integration of the Detection Units (DUs) in the KM3NeT experiment. In particular, the device is designed to seal the Break-out-box (BOB). The BOB is a box interface between a Digital Optical Module (DOM) and the electro-optical cable (VEOC) for power and optical connection of each optical module (DOM) to the DU. The original manual version of the tool developed by NIKHEF was then automatized by INFN-LNS in order to guarantee a replicable operation in the recursive process of the DU integration and two samples have been developed for the integration sites at LNS and Genova respectively. The general principle and performances of the automated welding machine will be presented shortly in a dedicated INFN report. Here we summarize the cycle of the operations performed by the machine and how they are managed by corresponding control program and related electronics boards

The integration of the detection units of KM3NET in Genova

The KM3NeT experiment (1) for the detection of high energy cosmic neutrinos is being built in two sites of the Mediterranean Sea: Capo Passero in Sicily and Toulon in the French coast. The full detection system includes 3 building blocks of Detection Units (DU) (2), each block of 115 DUs. The DU accommodates up to 18 digital optical modules (DOMs) (3). In this note we describe the facility to integrate the DOMs to the vertical cable of the line (VEOC) as realized in our ground floor laboratory of the INFN Institute in Genova

Constraints on new physics from the quark mixing unitarity triangle

The status of the Unitarity Triangle beyond the Standard Model including the most recent results on Delta m_s, on dilepton asymmetries and on width differences is presented. Even allowing for general New Physics loop contributions the Unitarity Triangle must be very close to the Standard Model result. With the new measurements from the Tevatron, we obtain for the first time a significant constraint on New Physics in the B_s sector. We present the allowed ranges of New Physics contributions to Delta F=2 processes, and of the time-dependent CP asymmetry in B_s to J/Psi phi decays.Comment: 5 pages, 4 figures. v2: numerical error in Delta Gamma_s/Gamma_s corrected. Plots and tables updated. v3: update after ICHEP06, final version published in Phys Rev Letter

Characterization of soot produced by the mini inverted soot generator with an atmospheric simulation chamber

The performance of a mini inverted soot generator (MISG) has been investigated at ChAMBRe (Chamber for Aerosol Modelling and Bio-aerosol Research) by studying the properties of soot particles generated by ethylene and propane combustion. This work deepens and expands the existing characterization of the MISG, which also exploits an atmospheric simulation chamber (ASC). Different from previous works, MISG performance has been also tested at different fuel flows and higher global equivalence ratios. MISG exhausts were investigated after their injection inside the atmospheric simulation chamber, which is another novelty of this work. Starting from an extensive classification of combustion conditions and resulting flame shapes, the MISG exhaust was characterized in terms of concentration of emitted particles and gases, particle size distribution, and optical properties. Soot particles were also collected on quartz fibre filters and then analysed by optical and thermal\u2013optical techniques to measure the spectral dependence of the absorption coefficient babs and their composition in terms of elemental carbon and organic carbon (EC and OC). Significant differences could be observed when the MISG was fuelled with ethylene and propane in terms of particle size. In particular, the production of super-micrometric aggregates was observed for ethylene combustion. With equal combustion conditions, ethylene produced a higher number concentration of particles and smaller mode diameters. Soot particles produced by propane combustion resulted in higher EC : TC (total carbon) ratios and they were more light absorbing than particles generated by ethylene combustion. Values of the mass absorption cross section (MAC) and of the \uc5ngstr\uf6m absorption exponent (AAE) turned out to be compatible with the literature, even if there were some specific differences. The comprehensive characterization of the MISG soot particles is an important piece of information to design and perform experiments in atmospheric simulation chambers. Particles with well-known properties can be used, for example, to investigate the possible interactions between soot and other atmospheric pollutants, the effects of meteorological variables on soot properties, and the oxidative and toxicological potential of soot particles

ChAMBRe \u2013 the development of an atmosferic simulation chamber for bioaerosol studies and aerosol optical properties investigation

Environmental simulation chambers are small to largescale facilities where atmospheric conditions can be monitored in real-time under control to reproduce realistic environments and to study interactions among their constituents. Up to now, they have been used mainly to study chemical and photochemical processes that occur in the atmosphere, but the high versatility of these facilities allows for a wider application covering all fields of atmospheric aerosol science. ChAMBRe (Chamber for Aerosol Modelling and Bioaerosol Research) is the stainless steel atmospheric simulation chamber (volume approximately 3 m3, see Figure 1) recently installed at the National Institute of Nuclear Physics in Genoa (INFN-Genova) in collaboration with the Environmental Physics Laboratory at the Physics Department of Genoa University (www.labfisa.ge.infn.it). The scientific activities at ChAMBRe focus on the following topics: 1) Bioaerosol properties A strong improvement in the understanding of bioaerosol behaviour can be provided by atmospheric chamber experiments, that allow for a scientific intermediate approach between \u201cin vitro\u201d and \u201cin vivo\u201d analysis. Aerosol with realistic composition, including living micro-organisms, can be injected in artificial environments with controlled physical and chemical parameters and then accurately analyzed. In particular, a systematic approach can be used for a better description of micro-organisms viability, of colonies growing modulation and other issues relevant to their spread and their pathogenicity. Very promising results in this direction were obtained by the authors at the CESAM facility at CNRS-LISA (Brotto et al. 2015), while similar results were obtained nearly at the same time at AIDA chamber at KIT (Amato et al. 2015). ChAMBRe experiments are carrying on this path to contribute in getting a deeper understanding of the still unclear mechanisms that control the evolution of bioaerosols in atmosphere and in particular of their bacterial components. 2) Aerosol optical properties \u2013 methodologies and instruments testing The instrumental development efforts at the Environmental Physics Laboratory of the University of Genoa, recently resulted in a new Multi Wavelength Absorbance Analyser (Massab\uf2 et al. 2015) which measure the light absorption on aerosol loaded filters at five wavelengths from UV (absorption bands of organic compounds, mineral dust) to near infrared (carbon soot,\u2026). Furthermore, a new data reduction methodology has been introduced to disentangle the concentration of Black and Brown carbon in atmospheric aerosol, demonstrating the need to mitigate not only exhaust but also non-exhaust emissions, as a potentially important source of PM10. The atmospheric chamber is an effective tool to produce known aerosol mixtures and to test the performance of the optical technology. Actually, there is an on-going collaboration with the CNRS-LISA team working at CESAM following that procedure that will be soon replicated at ChAMBRe facility. ChAMBRe has recently joined the Eurochamp consortium, the European atmospheric chamber facilities network. The network activities have been included in an infrastructure-oriented research project proposal that is going to be submitted within March 2016 to the H2020-INFRAIA call within EU Horizon 2020 Programme. We would like to acknowledge prof. J.F. Doussin and LISA laboratories (http://www.lisa.univ-paris12.fr/en) for providing us part of the chamber structure and for the very useful and fruitful technical discussions