886 research outputs found
Kaons in Dense Half-Skyrmion Matter
Dense hadronic matter at low temperature is expected to be in crystal and at
high density make a transition to a {\em chirally restored but color-confined}
state which is a novel phase hitherto unexplored. This phase transition is
predicted in both skyrmion matter in 4D and instanton matter in 5D, the former
in the form of half-skyrmions and the latter in the form of half-instantons or
dyons. We predict that when 's are embedded in this half-skyrmion or
half-instanton (dyonic) matter which may be reached not far above the normal
density, there arises an enhanced attraction from the soft dilaton field
figuring for the trace anomaly of QCD and the Wess-Zumino term. This attraction
may have relevance for a possible strong binding of anti-kaons in dense nuclear
matter and for kaon condensation in neutron-star matter. Such kaon property in
the half-skyrmion phase is highly non-perturbarive and may not be accessible by
low-order chiral perturbation theory. Relevance of the half-skyrmion or dyonic
matter to compact stars is discussed.Comment: 5 pages, 2 figure
Inventory Model with Seasonal Demand: A Specific Application to Haute Couture
In the stochastic multiperiod inventory problem, a vast majority of the literature deals with demand volume uncertainty. Other dimensions of uncertainty have generally been overlooked. In this paper, we develop a newsboy formulation for the aggregate multiperiod inventory problem intended for products of short sales season and without replenishments. A distinguishing characteristic of our formulation is that it takes a time dimension of demand uncertainty into account. The proposed model is particularly suitable for applications in haute couture, i.e., high fashion industry. The model determines the time of switching primary sales effort from one season to the next as well as optimal order quantity for each season with the objective of maximizing expected profit over the planning horizon. We also derive the optimality conditions for the time of switching primary sales effort and order quantity. Furthermore, we show that if time uncertainty and volume uncertainty are independent, order quantity becomes the main decision over the interval of the primary selling season. Finally, we demonstrate that the results from the two-season case can be directly extended to the multi-season case and the limited resource multiple-item case
Topological Structure of Dense Hadronic Matter
We present a summary of work done on dense hadronic matter, based on the
Skyrme model, which provides a unified approach to high density, valid in the
large limit. In our picture, dense hadronic matter is described by the
{\em classical} soliton configuration with minimum energy for the given baryon
number density. By incorporating the meson fluctuations on such ground state we
obtain an effective Lagrangian for meson dynamics in a dense medium. Our
starting point has been the Skyrme model defined in terms of pions, thereafter
we have extended and improved the model by incorporating other degrees of
freedom such as dilaton, kaons and vector mesons.Comment: 13 pages, 8 figures, Talk given at the KIAS-APCTP Symposium in
Astro-Hadron Physics "Compact Stars: Quest for New States of Dense Matter",
November 10-14, 2003, Seoul, Korea, published by World Scientific. Based on
talk by B.-Y. Par
Integrating Product Platform Development with Supply Chain Configuration in a Global Environment
Unified Approach to Dense Matter
We apply the Skyrme model to dense hadronic matter, which provides a unified
approach to high density, valid in the large Nc limit. In our picture, dense
hadronic matter is described by the classical soliton configuration with
minimum energy for the given baryon number density. By incorporating the meson
fluctuations on such ground state we obtain an effective Lagrangian for meson
dynamics in a dense medium. Our starting point has been the Skyrme model
defined in terms of pions, thereafter we have extended and improved the model
by incorporating other degrees of freedom such as dilaton, kaons and vector
mesons.Comment: 6 pages, 4 figures, a talk given at the international conference QCD
DOWN UNDER, March 10 - 19, Adelaide, Australi
DNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 gene
Selectivity and sensitivity in the detection of single nucleotide polymorphisms (SNPs) are among most important attributes to determine the performance of DNA microarrays. We previously reported the generation of a novel mesospaced surface prepared by applying dendron molecules on the solid surface. DNA microarrays that were fabricated on the dendron-modified surface exhibited outstanding performance for the detection of single nucleotide variation in the synthetic oligonucleotide DNA. DNA microarrays on the dendron-modified surface were subjected to the detection of single nucleotide variations in the exons 5–8 of the p53 gene in genomic DNAs from cancer cell lines. DNA microarrays on the dendron-modified surface clearly discriminated single nucleotide variations in hotspot codons with high selectivity and sensitivity. The ratio between the fluorescence intensity of perfectly matched duplexes and that of single nucleotide mismatched duplexes was >5–100 without sacrificing signal intensity. Our results showed that the outstanding performance of DNA microarrays fabricated on the dendron-modified surface is strongly related to novel properties of the dendron molecule, which has the conical structure allowing mesospacing between the capture probes. Our microarrays on the dendron-modified surface can reduce the steric hindrance not only between the solid surface and target DNA, but also among immobilized capture probes enabling the hybridization process on the surface to be very effective. Our DNA microarrays on the dendron-modified surface could be applied to various analyses that require accurate detection of SNPs
Bioinformatic Analysis of Nematode Migration-Associated Genes Identifies Novel Vertebrate Neural Crest Markers
Neural crest cells are highly motile, yet a limited number of genes governing neural crest migration have been identified by conventional studies. To test the hypothesis that cell migration genes are likely to be conserved over large evolutionary distances and from diverse tissues, we searched for vertebrate homologs of genes important for migration of various cell types in the invertebrate nematode and examined their expression during vertebrate neural crest cell migration. Our systematic analysis utilized a combination of comparative genomic scanning, functional pathway analysis and gene expression profiling to uncover previously unidentified genes expressed by premigratory, emigrating and/or migrating neural crest cells. The results demonstrate that similar gene sets are expressed in migratory cell types across distant animals and different germ layers. Bioinformatics analysis of these factors revealed relationships between these genes within signaling pathways that may be important during neural crest cell migration
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