Pedagogical culture as one of the faces of organizational culture university

This article is about pedagogical culture as one of the faces of the organizational culture of the university. The components of pedagogical culture are considered in the article. Also in the article there is done the research of this question in three Novosibirsk universitiesВ статье рассматривается педагогическая культура как одна из граней организационной культуры вуза. Рассмотрены составляющие педагогической культуры. В качестве примера приводится исследование данного вопроса в трех вузах города Новосибирск

From Coulomb excitation cross sections to non-resonant astrophysical rates in three-body systems: 17^{17}Ne case

Coulomb and nuclear dissociation of $^{17}$Ne on light and heavy targets are studied theoretically. The dipole E1 strength function is determined in a broad energy range including energies of astrophysical interest. Dependence of the strength function on different parameters of the $^{17}$Ne ground state structure and continuum dynamics is analyzed in a three-body model. The discovered dependence plays an important role for studies of the strength functions for the three-body E1 dissociation and radiative capture. The constraints on the $[s^2]/[d^2]$ configuration mixing in $^{17}$Ne and on $p$-wave interaction in the $^{15}$O+$p$ channel are imposed based on experimental data for $^{17}$Ne Coulomb dissociation on heavy target.Comment: 12 pages, 13 figure

Three-body correlations in direct reactions: Example of 6^{6}Be populated in (p,n)(p,n) reaction

The $^{6}$Be continuum states were populated in the charge-exchange reaction $^1$H($^{6}$Li,$^{6}$Be)$n$ collecting very high statistics data ($\sim 5 \times 10^6$ events) on the three-body $\alpha$+$p$+$p$ correlations. The $^{6}$Be excitation energy region below $\sim 3$ MeV is considered, where the data are dominated by contributions from the $0^+$ and $2^+$ states. It is demonstrated how the high-statistics few-body correlation data can be used to extract detailed information on the reaction mechanism. Such a derivation is based on the fact that highly spin-aligned states are typically populated in the direct reactions.Comment: submitted to Physical Review

10He low-lying states structure uncovered by correlations

The 0+ ground state of the 10He nucleus produced in the 3H(8He,p)10He reaction was found at about $2.1\pm0.2$ MeV (\Gamma ~ 2 MeV) above the three-body 8He+n+n breakup threshold. Angular correlations observed for 10He decay products show prominent interference patterns allowing to draw conclusions about the structure of low-energy excited states. We interpret the observed correlations as a coherent superposition of the broad 1- state having a maximum at energy 4-6 MeV and the 2+ state above 6 MeV, setting both on top of the 0+ state "tail". This anomalous level ordering indicates that the breakdown of the N=8 shell known in 12Be thus extends also to the 10He system.Comment: 5 pages, 5 figure

Involvement of Urokinase-Type Plasminogen Activator Receptor in the Formation of a Profibrotic Microenvironment in the Epicardial Region

The study of the mechanisms of development and progression of fibrosis is one of the key directions of modern cardiology. Our work suggests that the urokinase receptor (uPAR) is involved in the regulation of mesothelial cell activity and epicardial fibrosis development, which, when interacting with specific ligands and intermediate proteins, can activate intracellular signaling, trigger the cascade of proteolytic reactions, including local plasmin formation and activation of matrix metalloproteinases, providing matrix remodeling.Objective: to perform a comparative study of fibrogenic activity of the epicardium in the hearts of uPAR-/- and wild-type animals and evaluate the effect of cardiac microenvironment factors on the migration activity of epicardial mesothelial cells.Material and methods. We used histological and immunofluorescent staining, microarray analysis of proinflammatory cytokine levels, and a method for assessing the migratory properties of epicardial cells.Results. Results. We found that compared to wild-type animals, uPAR-/- animals show significant thickening of the epicardial area (2.46+0.77 (uPAR-/- mice) and 1.02+0.17 (Wt mice) relative units, P=0.033) accompanied by accumulation of extracellular matrix proteins. Deficiency of uPAR gene leads to formation of proinflammatory microenvironment in the heart (increased levels of proinflammatory factors such as IL-1, IL-13, IL-17, RANTES and MIP1), increased migratory activity of epicardial mesothelial cells, accumulation of TCF21+fibroblast/myofibroblast precursors (29.8+13.7 (uPAR-/- mouse) and 3.03+0.8 (Wt mouse) cells per visual field,P=0.02), as well as development of subepicardial fibrosis.Conclusion. These findings suggest that uPAR is a promising candidate for the developing targeted agents to prevent the development and progression of cardiac fibrosis

Experience in Utilization of Phylogenetic Analysis for Epidemiological Investigation of HIV Infection Case

Objective of the study was to investigate a criminal case of infection with HIV, applying molecular-genetic analysis of blood plasma samples from an estimated source of an infection and the recipient for evaluation of probability of epidemiological connection between them. Materials and methods. The study involved genotyping and phylogenetic analysis of nucleotide sequences of HIV-1 variants, isolated from patients in the investigated group and the control one (19 nucleotide sequences of the HIV-1 from the patients living in the Saratov region, and 15 nucleotide sequences from GenBank). Genotyping was performed using the commercial ViroSeq HIV-1 Genotyping System. The sub-typing of HIV-1 strains was carried out on-line, through the COMET HIV-1/2 and HCV and REGA HIV-1 Sybtyping Tool programs. Phylogenetic analysis of nucleotide sequences was carried out by Mega software, version 5.2. Phylogenetic trees were constructed; nucleotide distances were calculated by Kimura method (bootstrap level 1000). Results and conclusions. Virus variants, isolated from the studied samples, were defined as HIV-1 A subtype. Performed phylogenetic analysis showed that nucleotide sequences of the studied samples authentically grouped on the phylogenetic tree, forming a common cluster, which mismatched that of control group. Calculation of the genetic distance testifies that the genetic relation between the samples within the investigated group is higher, than between the same samples and those of the control group. Thus, by means of phylogenetic analysis it is shown that the strains received from an estimated source of infection and the recipient are genetically closer to each other, than to the strains from the group of comparison. In this regard, it is possible to claim with a big share of confidence that probability of epidemiological connection between them exists

The observation of long-range three-body Coloumb effects in the decay of 16Ne

The interaction of an $E/A$=57.6-MeV $^{17}$Ne beam with a Be target was used to populate levels in $^{16}$Ne following neutron knockout reactions. The decay of $^{16}$Ne states into the three-body $^{14}$O+$p$+$p$ continuum was observed in the High Resolution Array (HiRA). For the first time for a 2p emitter, correlations between the momenta of the three decay products were measured with sufficient resolution and statistics to allow for an unambiguous demonstration of their dependence on the long-range nature of the Coulomb interaction. Contrary to previous experiments, the intrinsic decay width of the $^{16}$Ne ground state was found to be narrow ($\Gamma<60$~keV), consistent with theoretical estimates.Comment: 6 pages, 5 figure

Search for 2p Decay of the First Excited State of 17 Ne

Structure of nuclei located near and beyond the drip-lines plays important role in the explosive astrophysical processes. The problem of two-proton decay of the 17Ne first excited state is a good example of such situation. The two-proton radiative capture is a possible bypass of the 15O waiting point in the rp-process. The rate of this process drastically depends on the value of the weak