X-ray observations of the Ultraluminous infrared galaxy IRAS19254-7245 (The Superantennae)

We present ROSAT HRI and ASCA observations of the well known ULIRG IRAS19254-7245 (the Superantennae). The object is not detected by ROSAT yielding a 3\sigma upper limit of L_x ~8x10^{41} erg/s in the 0.1-2 keV band. However, we obtain a clear detection by ASCA yielding a luminosity in the 2-10 keV band of 2 \times 10^{42}erg/s. Its X-ray spectrum is very hard, equivalent to a photon index of Gamma=1.0+-0.35. We therefore, attempt to model the X-ray data with a "scatterer" model in which the intrinsic X-ray emission along our line of sight is obscured by an absorbing screen while some fraction, f, is scattered into our line of sight by an ionized medium; this is the standard model for the X-ray emission in obscured (but non Compton-thick) Seyfert galaxies. We obtain an absorbing column of 2x10^{23}cm^{-2} for a power-law photon index of Gamma=1.9, an order of magnitude above the column estimated on the basis of optical observations; the percentage of the scattered emission is high (~20%). Alternatively, a model where most of the X-ray emission comes from reflection on a Compton thick torus (N_H>10^{24} cm^{-2}) cannot be ruled out. We do not detect an Fe line at 6.4 keV; however, the upper limit (90%) to the equivalent width of the 6.4 keV line is high (~3 keV). All the above suggest that most of the X-ray emission originates in an highly obscured Seyfert-2 nucleus.Comment: 5 pages, 1 figure, 1 table, To appear in MNRA

Type 0 Brane Inflation from Mirage Cosmology

We consider a three-dimensional brane-universe moving in a Type 0 String background. The motion induces on the brane a cosmological evolution which, for some range of the parameters, exhibits an inflationary phase.Comment: 11 pages, latex, one figur

Inflation Induced by Vacuum Energy and Graceful Exit from it

Motivated by brane cosmology we solve the Einstein equations with a time dependent cosmological constant. Assuming that at an early epoch the vacuum energy scales as $1/logt$, we show that the universe passes from a fast growing phase (inflation) to an expanding phase in a natural way

Cosmological Evolution in a Type-0 String Theory

We study the cosmological evolution of a type-0 string theory by employing non-criticality, which may be induced by fluctuations of the D3 brane worlds. We check the consistency of the approach to O(alpha ') in the corresponding sigma-model. The ten-dimensional theory is reduced to an effective four-dimensional model, with only time dependent fields. We show that the four-dimensional universe has an inflationary phase and graceful exit from it, while the other extra dimensions are stabilized to a constant value, with the fifth dimension much larger than the others. We pay particular attention to demonstrating the role of tachyonic matter in inducing these features. The Universe asymptotes, for large times, to a non-accelerating linearly-expanding Universe with a time-dependent dilaton and a relaxing to zero vacuum energy a la quintessence.Comment: 33 pages LATEX, seven eps figures incorporate

The Effect of Social Feedback in a Reddit Weight Loss Community

This is a preprint of an article appearing at ACM Digital Health 201

The X-ray spectra of optically selected Seyfert 2 galaxies. Are there any Sy2 galaxies with no absorption?

We present an X-ray spectral analysis of a sample of 8 bona-fide Seyfert 2 galaxies, selected on the basis of their high $[OIII]\lambda5007$ flux, from the Ho et al. (1997) spectroscopic sample of nearby galaxies. We find that, in general, the X-ray spectra of our Seyfert 2 galaxies are complex, with some our objects having spectra different from the 'typical' spectrum of X-ray selected Seyfert 2 galaxies. Two (NGC3147 and NGC4698) show no evidence for intrinsic absorption. We suggest this is due to the fact that when the torus suppresses the intrinsic medium and hard energy flux, underlying emission from the host galaxy, originating in circumnuclear starbursts, and scattering from warm absorbers contributes in these energy bands more significantly. Our asca data alone cannot discriminate whether low absorption objects are Compton-thick AGN with a strong scattered component or lack an obscuring torus. The most striking example of our low absorption Seyfert 2 is NGC4698. Its spectrum could be explained by either a dusty warm absorber or a lack of broad line clouds so that its appearance as a Seyfert 2 is intrinsic and not due to absorption.Comment: 12 pages, to be published in MNRA

Library and information resources and users of digital resources in the humanities

Purpose – The purpose of this article is to discuss the results of the Log Analysis of Internet Resources in the Arts and Humanities (LAIRAH) study. It aims to concentrate upon the use and importance of information resources, physical research centres and digital finding aids in scholarly research. Design/methodology/approach – Results are presented of web server log analysis of portals for humanities scholars: the arts and humanities data service (AHDS) website and Humbul Humanities Hub. These are used to determine which resources were accessed most often, or seldom. Questionnaire data about perceptions of digital resource use were also gathered. Findings – Information resources such as libraries, archives museums and research centres, and the web pages that provide information about them are vital for humanities scholars. The university library website was considered to be the most important resource, even compared to Google. Secondary finding aids and reference resources are considered more important than primary research resources, especially those produced by other scholars, whose output is less trusted than publications produced by commercial organisations, libraries, archives and museums. Practical implications – Digital resources have not replaced physical information resources and the people who staff them, thus both types of information continue to require funding. Scholars trust the judgment of information professionals, who therefore need to be trained to evaluate and recommend specialist digital research resources. Originality/value – LAIRAH was the first research project to use quantitative data to investigate resource use. Findings about the type of resources used are based on evidence rather than opinions alone. This gives a clearer picture of usage that may be used to plan future information services

Mitochondrial Metabolism in Astrocytes Regulates Brain Bioenergetics, Neurotransmission and Redox Balance

In the brain, mitochondrial metabolism has been largely associated with energy production, and its dysfunction is linked to neuronal cell loss. However, the functional role of mitochondria in glial cells has been poorly studied. Recent reports have demonstrated unequivocally that astrocytes do not require mitochondria to meet their bioenergetics demands. Then, the question remaining is, what is the functional role of mitochondria in astrocytes? In this work, we review current evidence demonstrating that mitochondrial central carbon metabolism in astrocytes regulates overall brain bioenergetics, neurotransmitter homeostasis and redox balance. Emphasis is placed in detailing carbon source utilization (glucose and fatty acids), anaplerotic inputs and cataplerotic outputs, as well as carbon shuttles to neurons, which highlight the metabolic specialization of astrocytic mitochondria and its relevance to brain function

Secure certification of mixed quantum states with application to two-party randomness generation

We investigate sampling procedures that certify that an arbitrary quantum state on $n$ subsystems is close to an ideal mixed state $\varphi^{\otimes n}$ for a given reference state $\varphi$, up to errors on a few positions. This task makes no sense classically: it would correspond to certifying that a given bitstring was generated according to some desired probability distribution. However, in the quantum case, this is possible if one has access to a prover who can supply a purification of the mixed state. In this work, we introduce the concept of mixed-state certification, and we show that a natural sampling protocol offers secure certification in the presence of a possibly dishonest prover: if the verifier accepts then he can be almost certain that the state in question has been correctly prepared, up to a small number of errors. We then apply this result to two-party quantum coin-tossing. Given that strong coin tossing is impossible, it is natural to ask "how close can we get". This question has been well studied and is nowadays well understood from the perspective of the bias of individual coin tosses. We approach and answer this question from a different---and somewhat orthogonal---perspective, where we do not look at individual coin tosses but at the global entropy instead. We show how two distrusting parties can produce a common high-entropy source, where the entropy is an arbitrarily small fraction below the maximum (except with negligible probability)

Chemical Characterization and Biological Evaluation of \u3ci\u3eEpilobium parviflorum\u3c/i\u3e Extracts in an In Vitro Model of Human Malignant Melanoma

Malignant melanoma is an aggressive type of skin cancer characterised by high metastatic capacity and mortality rate. On the other hand, Epilobium parviflorum is known for its medicinal properties, including its anticancer potency. In this context, we aimed to (i) isolate various extracts of E. parviflorum, (ii) characterize their phytochemical content, and (iii) determine their cytotoxic potential in an in vitro model of human malignant melanoma. To these ends, we utilized various spectrophotometric and chromatographic (UPLC-MS/MS) approaches to document the higher content of the methanolic extract in polyphenols, soluble sugars, proteins, condensed tannins, and chlorophylls -a and -b as opposed to those of dichloromethane and petroleum. In addition, the cytotoxicity profiling of all extracts was assessed through a colorimetric-based Alamar Blue assay in human malignant melanoma (A375 and COLO-679) as well as non-tumorigenic immortalized keratinocyte (HaCaT) cells. Overall, the methanolic extract was shown to exert significant cytotoxicity, in a timeand concentration-dependent manner, as opposed to the other extracts. The observed cytotoxicity was confined only to human malignant melanoma cells, whereas non-tumorigenic keratinocyte cells remained relatively unaffected. Finally, the expression levels of various apoptotic genes were assessed by qRT-PCR, indicating the activation of both intrinsic and extrinsic apoptotic cascades. Supplement attached below