An Error-Correcting Line Code for a HEP Rad-Hard Multi-GigaBit Optical Link

This paper presents a line encoding scheme designed for the GBT ASIC, a transceiver under development for a multigigabit optical link upgrade of the TTC system. A general overview of issues related to optical links placed in radiation environments is given, and the required properties of the line code discussed. A scheme that preserves the DC-balance of the line and allows forward error correction is proposed. It is implemented through the concatenation of scrambling, a Reed-Solomon error-correction scheme and the addition of an error-tolerant DC-balanced header. The properties of the code are verified for two different interleaving options, which achieve different error correction capability at different implementation costs. One of the two options was implemented in a fully digital ASIC fabricated in a 0.13 μm CMOS technology, and ASIC implementation details and test results are reported

Editorial: Special Issue on Deep Learning for Data Quality

This editorial summarizes the content of the Special Issue on Deep Learning for Data Quality of the Journal of Data and Information Quality (JDIQ)

Neuroendocrine bronchial and thymic tumors: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

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Cleaning data with Llunatic

Data cleaning (or data repairing) is considered a crucial problem in many database-related tasks. It consists in making a database consistent with respect to a given set of constraints. In recent years, repairing methods have been proposed for several classes of constraints. These methods, however, tend to hard-code the strategy to repair conflicting values and are specialized toward specific classes of constraints. In this paper, we develop a general chase-based repairing framework, referred to as Llunatic, in which repairs can be obtained for a large class of constraints and by using different strategies to select preferred values. The framework is based on an elegant formalization in terms of labeled instances and partially ordered preference labels. In this context, we revisit concepts such as upgrades, repairs and the chase. In Llunatic, various repairing strategies can be slotted in, without the need for changing the underlying implementation. Furthermore, Llunatic is the first data repairing system which is DBMS-based. We report experimental results that confirm its good scalability and show that various instantiations of the framework result in repairs of good quality

Synchronous Phase Shift at LHC

The electron cloud in vacuum pipes of accelerators of positively charged particle beams causes a beam energy loss which could be estimated from the synchronous phase. Measurements done with beams of 75 ns, 50 ns, and 25 ns bunch spacing in the LHC for some fills in 2010 and 2011 show that the average energy loss depends on the total beam intensity in the ring. Later measurements during the scrubbing run with 50 ns beams show the reduction of the electron cloud due to scrubbing. Finally, measurements of the individual bunch phase give us information about the electron cloud build-up inside the batch and from batch to batch.Comment: Presented at ECLOUD'12: Joint INFN-CERN-EuCARD-AccNet Workshop on Electron-Cloud Effects, La Biodola, Isola d'Elba, Italy, 5-9 June 201

Characteristics of the patients referred to a Hypertension Unit between 1989 and 2003

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Longitudinal Emittance Blow-Up in the LHC

The LHC relies on Landau damping for longitudinal stability. To avoid decreasing the stability margin at high energy, the longitudinal emittance must be continuously increased during the acceleration ramp. Longitudinal blow-up provides the required emittance growth. The method was implemented through the summer of 2010. We inject band-limited RF phase-noise in the main accelerating cavities during the whole ramp of about 11 minutes. Synchrotron frequencies change along the energy ramp, but the digitally created noise tracks the frequency change. The position of the noise-band, relative to the nominal synchrotron frequency, and the bandwidth of the spectrum are set by pre-defined constants, making the diffusion stop at the edges of the demanded distribution. The noise amplitude is controlled by feedback using the measurement of the average bunch length. This algorithm reproducibly achieves the programmed bunch length of about 1.2 ns (4 ) at flat top with low bunch-to-bunch scatter and provides a stable beam for physics coast

A modified vimentin histological score helps recognize pulmonary sarcomatoid carcinoma in small biopsy samples

Background: As pulmonary sarcomatoid carcinomas (PSCs) are life-threatening tumors, an improvement in their recognition in small-sized tumor samples is clinically warranted. Materials and Methods: Preoperative biopsy samples and paired surgical specimens from 20 pleomorphic carcinomas, two pulmonary blastomas and one carcinosarcoma (training set) were studied for vimentin immunohistochemistry. A modified vimentin histologic score (M-VHS) was devised by multiplying three independently assessed parameters, i.e. the percentage of positive cells (from 0 to 5+, by quintiles), the intensity of immunostaining (low=1 vs. strong=2) and the distribution pattern within the cytoplasm (partial=1 vs. diffuse=2), so ranging from 0 to 20. Forty-eight consecutive and independent cases of non-small cell lung carcinoma (NSCLC), including two additional cases of PSC, were used as control groups (validation set). Results: No differences in M-VHS were found between biopsies and surgical specimens of PSC, thus confirming the occurrence of stable epithelial mesenchymal transition (EMT) and hence the specific diagnosis of PSC. All types of PSC shared the same M-VHS. The M-VHS of 46 conventional NSCLC was by far lower (p<0.0001), whereas two additional cases of PSC showed the same results as the training set. Poorly differentiated NSCLC with marked pleomorphism but not stable EMT did not exhibit significantly increased M-VHS values. Conclusion: M-VHS helped in morphological analysis to render more definite diagnoses on small biopsies of PSC