10 research outputs found
AC-feasible Local Flexibility Market with Continuous Trading
This paper proposes a novel continuous Local Flexibility Market where active
power flexibility located in the distribution system can be traded. The market
design engages the Market Operator, the Distribution System Operator and Market
Participants with dispatchable assets. The proposed market operates in a single
distribution system and considers network constraints via AC network
sensitivities, calculated at an initial network operating point. Trading is
possible when AC network constraints are respected and when anticipated network
violations are alleviated or resolved. The implementation allows for partial
bid matching and is computationally light, therefore, suitable for continuous
trading applications. The proposed design is thoroughly described and is
demonstrated in a test distribution system. It is shown that active power
trading in the proposed market design can lead to resolution of line overloads.Comment: In proceedings of the 11th Bulk Power Systems Dynamics and Control
Symposium (IREP 2022), July 25-30, 2022, Banff, Canad
Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma
Recent transcriptomic-based analysis of diffuse large B cell lymphoma (DLBCL) has highlighted the clinical relevance of LN fibroblast and tumor-infiltrating lymphocyte (TIL) signatures within the tumor microenvironment (TME). However, the immunomodulatory role of fibroblasts in lymphoma remains unclear. Here, by studying human and mouse DLBCL-LNs, we identified the presence of an aberrantly remodeled fibroblastic reticular cell (FRC) network expressing elevated fibroblast-activated protein (FAP). RNA-Seq analyses revealed that exposure to DLBCL reprogrammed key immunoregulatory pathways in FRCs, including a switch from homeostatic to inflammatory chemokine expression and elevated antigen-presentation molecules. Functional assays showed that DLBCL-activated FRCs (DLBCL-FRCs) hindered optimal TIL and chimeric antigen receptor (CAR) T cell migration. Moreover, DLBCL-FRCs inhibited CD8+ TIL cytotoxicity in an antigen-specific manner. Notably, the interrogation of patient LNs with imaging mass cytometry identified distinct environments differing in their CD8+ TIL-FRC composition and spatial organization that associated with survival outcomes. We further demonstrated the potential to target inhibitory FRCs to rejuvenate interacting TILs. Cotreating organotypic cultures with FAP-targeted immunostimulatory drugs and a bispecific antibody (glofitamab) augmented antilymphoma TIL cytotoxicity. Our study reveals an immunosuppressive role of FRCs in DLBCL, with implications for immune evasion, disease pathogenesis, and optimizing immunotherapy for patients
Un manuscrit inconnu provenant de la bibliothèque de l'archonte phanariote Nikolaos Karatzas
REB 49 1991 France p. 255-261
G. K. Papazoglou, Un manuscrit inconnu provenant de la bibliothèque de l'archonte phanariote Nikolaos Karatzas. — Le manuscrit n° 3 de la bibliothèque de Harvard College, un Psautier du 12e siècle, provient du fonds réuni par l'archonte phanariote Nikolaos Karatzas, comme le manuscrit n° 1474 de la Bibliothèque Nationale de Grèce. Les deux manuscrits portent des notices dues à la même main.Papazoglou Georges K. Un manuscrit inconnu provenant de la bibliothèque de l'archonte phanariote Nikolaos Karatzas. In: Revue des études byzantines, tome 49, 1991. pp. 255-261
O Th. Phillipps και μια αγνωστη εκδοση καταλόγων ιδιωτικων βιβλιοθηκων της κωνσταντινούπολης
Papazoglou Georgios K. O Th. Phillipps και μια αγνωστη εκδοση καταλόγων ιδιωτικων βιβλιοθηκων της κωνσταντινούπολης. In: Scriptorium, Tome 39 n°2, 1985. pp. 292-293
Le Michel Cantacuzène du codex Mavrocordatianus et le possesseur homonyme du Psautier de Harvard
REB 46 1988 France p. 161-165
G. K. Papazoglou, Le Michel Cantacuzène du codex Mavrocordatianus et le possesseur homonyme du Psautier de Harvard. — L'auteur montre que le codex Mavrocordatianus conservé à la Knižnica Akadémie de Bratislava et le Psautier du 12e siècle donné en 1820 à la Bibliothèque de Harvard College ont appartenu à un seul et même Michel Cantacuzène, mort en 1578.Papazoglou Georges K. Le Michel Cantacuzène du codex Mavrocordatianus et le possesseur homonyme du Psautier de Harvard. In: Revue des études byzantines, tome 46, 1988. pp. 161-165
ƩΠAPAΓMATA des manuscrits de la bibliothèque du couvent Dionysiou du Mont-Athos
Papazoglou Georgios K. ƩΠAPAΓMATA des manuscrits de la bibliothèque du couvent Dionysiou du Mont-Athos. In: Scriptorium, Tome 44 n°1, 1990. pp. 98-103
Some Observation on the Relationship between Codex Vat. Pal. gr. 426 and the Manuscript of Ioannis Soutsos' Library
Papazoglou Georges K. Some Observation on the Relationship between Codex Vat. Pal. gr. 426 and the Manuscript of Ioannis Soutsos' Library. In: Scriptorium, Tome 41 n°2, 1987. pp. 271-273