48 research outputs found
Tourism income and economic growth in Greece: Empirical evidence from their cyclical components
This paper examines the relationship between the cyclical
components of Greek GDP and international tourism income for
Greece for the period 1976–2004. Using spectral analysis the authors
find that cyclical fluctuations of GDP have a length of about nine
years and that international tourism income has a cycle of about
seven years. The volatility of tourism income is more than eight
times the volatility of the Greek GDP cycle. VAR analysis shows that
the cyclical component of tourism income is significantly influencing
the cyclical component of GDP in Greece. The findings support the
tourism-led economic growth hypothesis and are of particular
interest and importance to policy makers, financial analysts and
investors dealing with the Greek tourism industry
Ensuring meiotic DNA break formation in the mouse pseudoautosomal region
In mice, the pseudoautosomal region of the sex chromosomes undergoes a dynamic structural rearrangement to promote a high rate of DNA double-strand breaks and to ensure X-Y recombination. Sex chromosomes in males of most eutherian mammals share only a small homologous segment, the pseudoautosomal region (PAR), in which the formation of double-strand breaks (DSBs), pairing and crossing over must occur for correct meiotic segregation(1,2). How cells ensure that recombination occurs in the PAR is unknown. Here we present a dynamic ultrastructure of the PAR and identify controlling cis- and trans-acting factors that make the PAR the hottest segment for DSB formation in the male mouse genome. Before break formation, multiple DSB-promoting factors hyperaccumulate in the PAR, its chromosome axes elongate and the sister chromatids separate. These processes are linked to heterochromatic mo-2 minisatellite arrays, and require MEI4 and ANKRD31 proteins but not the axis components REC8 or HORMAD1. We propose that the repetitive DNA sequence of the PAR confers unique chromatin and higher-order structures that are crucial for recombination. Chromosome synapsis triggers collapse of the elongated PAR structure and, notably, oocytes can be reprogrammed to exhibit spermatocyte-like levels of DSBs in the PAR simply by delaying or preventing synapsis. Thus, the sexually dimorphic behaviour of the PAR is in part a result of kinetic differences between the sexes in a race between the maturation of the PAR structure, formation of DSBs and completion of pairing and synapsis. Our findings establish a mechanistic paradigm for the recombination of sex chromosomes during meiosis.Peer reviewe
Experimental and theoretical studies of corrosion-induced mechanical properties degradation of aircraft 2024 aluminum alloy
The effect of Stone-Wales defect on the tensile behavior and fracture of single-walled carbon nanotubes
Thermal Green's functions in plane anisotropic bimaterials
Green's functions solutions are presented for the plane problems of a thermal source and a thermal dislocation near the interface between two anisotropic, perfectly bonded semi-infinite bodies with different thermo-mechanical properties. The analysis utilizes the complex potential approach for both beat conduction and thermoelastic problems, and the solutions are built on those of the homogeneous case obtained in the current work