53 research outputs found

    Genome sequences of two pseudorabies virus strains isolated in Greece

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    Pseudorabies virus (species Suid herpesvirus 1) belongs to the genus Varicellovirus, subfamily Alphaherpesvirinae, family Herpesviridae, and is the causative agent of an acute and frequently fatal disease that affects mainly pigs. Here, we report the genome sequences of two strains of this virus isolated in Greece in 2010

    Joseph-Pierre Éléonord Pétrequin (1809-1876), the majestic French surgeon who introduced the concept of surgical anatomy

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    Pétrequin was a French surgeon born in the town of Villeurbanne, near the city of Lyon. He lived in an era when surgery was evolving towards a more complex and modern specialty. His magnificent career was shared between surgical pathology and history of surgery. His two most significant works were “Traité d’anatomie médico-chirurgicale et topographique” (An Assay of Medical and Surgical Anatomy and Topography) and “La chirurgie d’Hippocrate” (The Surgery of Hippocrates). Having realized the need for surgery to be combined with anatomy, he was the scholar who introduced the concept of surgical anatomy. His innovations, travels and publications won him a series of nominations and a place among th greatest European surgeons and philosophers of all times

    multicenter cohort study

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    Publisher Copyright: © 2023 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.Objective: Monochorionic (MC) triplet pregnancies are extremely rare and information on these pregnancies and their complications is limited. We aimed to investigate the risk of early and late pregnancy complications, perinatal outcome and the timing and methods of fetal intervention in these pregnancies. Methods: This was a multicenter retrospective cohort study of MC triamniotic (TA) triplet pregnancies managed in 21 participating centers around the world from 2007 onwards. Data on maternal age, mode of conception, diagnosis of major fetal structural anomalies or aneuploidy, gestational age (GA) at diagnosis of anomalies, twin-to-twin transfusion syndrome (TTTS), twin anemia–polycythemia sequence (TAPS), twin reversed arterial perfusion (TRAP) sequence and or selective fetal growth restriction (sFGR) were retrieved from patient records. Data on antenatal interventions were collected, including data on selective fetal reduction (three to two or three to one), laser surgery and any other active fetal intervention (including amniodrainage). Data on perinatal outcome were collected, including numbers of live birth, intrauterine demise, neonatal death, perinatal death and termination of fetus or pregnancy (TOP). Neonatal data such as GA at birth, birth weight, admission to neonatal intensive care unit and neonatal morbidity were also collected. Perinatal outcomes were assessed according to whether the pregnancy was managed expectantly or underwent fetal intervention. Results: Of an initial cohort of 174 MCTA triplet pregnancies, 11 underwent early TOP, three had an early miscarriage, six were lost to follow-up and one was ongoing at the time of writing. Thus, the study cohort included 153 pregnancies, of which the majority (92.8%) were managed expectantly. The incidence of pregnancy affected by one or more fetal structural abnormality was 13.7% (21/153) and that of TRAP sequence was 5.2% (8/153). The most common antenatal complication related to chorionicity was TTTS, which affected just over one quarter (27.6%; 42/152, after removing a pregnancy with TOP < 24 weeks for fetal anomalies) of the pregnancies, followed by sFGR (16.4%; 25/152), while TAPS (spontaneous or post TTTS with or without laser treatment) occurred in only 4.6% (7/152) of pregnancies. No monochorionicity-related antenatal complication was recorded in 49.3% (75/152) of pregnancies. Survival was apparently associated largely with the development of these complications: there was at least one survivor beyond the neonatal period in 85.1% (57/67) of pregnancies without antenatal complications, in 100% (25/25) of those complicated by sFGR and in 47.6% (20/42) of those complicated by TTTS. The overall rate of preterm birth prior to 28 weeks was 14.5% (18/124) and that prior to 32 weeks' gestation was 49.2% (61/124). Conclusion: Monochorionicity-related complications, which can impact adversely perinatal outcome, occur in almost half of MCTA triplet pregnancies, creating a challenge with regard to counseling, surveillance and management.publishersversionpublishe

    Association between T2-related co-morbidities and effectiveness of biologics in severe asthma

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    Acknowledgments The authors thank Mr. Joash Tan (BSc, Hons), of the Observational and Pragmatic Research Institute (OPRI), and Ms Andrea Lim (BSc, Hons) of the Observational Pragmatic Research Institute (OPRI) for their editorial and formatting assistance that supported the development of this publication. Funding statement: This study was conducted by the Observational and Pragmatic Research Institute (OPRI) Pte Ltd and was partially funded by Optimum Patient Care Global and AstraZeneca Ltd. AstraZeneca UK LimitedPeer reviewe

    A Comparative Evaluation of Hydromorphological Assessment Methods Applied in Rivers of Greece

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    The ecological assessment of all surface water bodies in Europe according to the Water Framework Directive involves the monitoring of biological, physicochemical and hydromorphological quality elements. For the hydromorphological assessment in particular, there are numerous methods that have been developed and adopted by EU member countries. With this study, we compared three different methods (River Habitat Survey, Morphological Quality Index and River Hydromorphology Assessment Technique) applied in 122 river reaches that are part of the National Monitoring Network of Greece. The main objectives were (a) to identify whether different assessment systems provide similar classifications of hydromorphological status and (b) to distinguish strengths and weaknesses associated with the implementation of each method. Our results show that the River Hydromorphology Assessment Technique (RHAT) and the Morphological Quality Index (MQI) resulted in the same classification for 58% of the studied reaches, while 34% of the remaining cases differed by only one quality class. Correlations between the two indices per river type (ICT) showed that the two indices were strongly correlated for water courses located at low altitudes. Concerning the HMS index of the River Habitat Survey (RHS), which is an index that reflects the overall hydromorphological pressure, it showed larger differences with the other two indices, mainly because it classified more sites as &ldquo;Poor&rdquo; and &ldquo;Bad&rdquo; quality classes. Based on our results, we recommend that the two indices, RHAT and MQI, can be implemented complementary to the RHS for providing a rather easy and quick assessment of the overall hydromorphological status, at least until a national hydromorphological database is compiled that will allow for the proper adaptation of the Habitat Quality Assessment (HQA) index

    Dietary Patterns of Greek Adults and Their Associations with Serum Vitamin D Levels and Heel Quantitative Ultrasound Parameters for Bone Health

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    The aim of this study is to investigate the dietary patterns which indicate the nutritional habits of Greek adults and their effects on serum 25(OH)D levels and quantitative ultrasound (QUS) parameters for bone health. This study is part of OSTEOS, an observational cross-sectional study. In total, 741 adults from rural and urban areas throughout Greece were recruited. A validated food frequency questionnaire (FFQ) was used for assessment of the population&rsquo;s dietary habits. Serum 25(OH)D was measured by enzyme immunoassay; QUS parameters were assessed with an Achilles device. Principal component analysis (PCA) was carried out for dietary pattern determination, and univariate analysis of variance was used for the assessment of 25(OH)D, broadband ultrasound attenuation (BUA), speed of sound (SOS), and stiffness index (SI) determinants. Six dietary patterns explain 52.2% of the variability of Greek adults&rsquo; nutritional habits. The &lsquo;vegetables&ndash;fruit&rsquo; dietary pattern explains the biggest rate of variability. Determinants of serum 25(OH)D are body mass index (BMI), elderly status, summer sun exposure, organized physical activity, a &lsquo;healthy&rsquo; pattern in winter months, and adherence to a &lsquo;sweet&rsquo; pattern. Determinants of QUS parameters are age, BMI, sedentary time, organized physical activity participation, and adherence to a &lsquo;healthy&rsquo; pattern

    Pressures and Status of the Riparian Vegetation in Greek Rivers: Overview and Preliminary Assessment

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    Riparian zones play an important role in the ecological stability of rivers. In particular, the quality of the riparian vegetation is a significant component of the hydromorphological status. In Europe, the QBR index (Qualitat del Bosc de Ribera) and the River Habitat Survey (RHS) are commonly used for the qualitative assessment of the riparian vegetation. In this study, we estimated the QBR index and the Riparian Quality index, which is derived from the RHS method, for 123 river reaches of the National Monitoring Network of Greece. Our field work included the completion of RHS and QBR protocols, as well as the use of Unmanned Aerial Vehicles (UAVs). The aim of this study is to assess the riparian vegetation status and to identify linkages with the dominant land uses within the catchment. Correlation analysis was used to identify the relationships between hydromorphological alterations and the degradation of the riparian vegetation, as well as their connection to land uses in the catchment area. Our results highlighted severe modifications of the riparian vegetation for the majority of the studied reaches. We also showed a differentiation of the QBR with respect to changes in the altitude and the land uses in the catchment area. Overall QBR reflects the variation in the riparian vegetation quality better than RQI. Our findings constitute an assessment of the status of the riparian zones in Greek rivers and set the basis for further research for the development of new and effective tools for a rapid quality assessment of the riparian zones

    A Comparative Evaluation of Hydromorphological Assessment Methods Applied in Rivers of Greece

    No full text
    The ecological assessment of all surface water bodies in Europe according to the Water Framework Directive involves the monitoring of biological, physicochemical and hydromorphological quality elements. For the hydromorphological assessment in particular, there are numerous methods that have been developed and adopted by EU member countries. With this study, we compared three different methods (River Habitat Survey, Morphological Quality Index and River Hydromorphology Assessment Technique) applied in 122 river reaches that are part of the National Monitoring Network of Greece. The main objectives were (a) to identify whether different assessment systems provide similar classifications of hydromorphological status and (b) to distinguish strengths and weaknesses associated with the implementation of each method. Our results show that the River Hydromorphology Assessment Technique (RHAT) and the Morphological Quality Index (MQI) resulted in the same classification for 58% of the studied reaches, while 34% of the remaining cases differed by only one quality class. Correlations between the two indices per river type (ICT) showed that the two indices were strongly correlated for water courses located at low altitudes. Concerning the HMS index of the River Habitat Survey (RHS), which is an index that reflects the overall hydromorphological pressure, it showed larger differences with the other two indices, mainly because it classified more sites as “Poor” and “Bad” quality classes. Based on our results, we recommend that the two indices, RHAT and MQI, can be implemented complementary to the RHS for providing a rather easy and quick assessment of the overall hydromorphological status, at least until a national hydromorphological database is compiled that will allow for the proper adaptation of the Habitat Quality Assessment (HQA) index
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