8 research outputs found
Small bowel Crohn’s disease: MR enteroclysis and capsule endoscopy compared to balloon-assisted enteroscopy
New modalities are available to visualize the small bowel in patients with Crohn’s disease (CD). The aim of this study was to compare the diagnostic yield of magnetic resonance enteroclysis (MRE) and capsule endoscopy (CE) to balloon-assisted enteroscopy (BAE) in patients with suspected or established CD of the small bowel. Consecutive, consenting patients first underwent MRE followed by CE and BAE. Patients with high-grade stenosis at MRE did not undergo CE. Reference standard for small bowel CD activity was a combination of BAE and an expert panel consensus diagnosis. Analysis included 38 patients, 27 (71%) females, mean age 36 (20–74) years, with suspected (n = 20) or established (n = 18) small bowel CD: 16 (42%) were diagnosed with active CD, and 13 (34%) by MRE with suspected high-grade stenosis, who consequently did not undergo CE. The reference standard defined high-grade stenosis in 10 (26%) patients. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value of MRE and CE for small bowel CD activity were 73 and 57%, 90 and 89%, 88 and 67%, and 78 and 84%, respectively. CE was complicated by capsule retention in one patient. MRE has a higher sensitivity and PPV than CE in small bowel CD. The use of CE is considerably limited by the high prevalence of stenotic lesions in these patients
Histologic and Histomorphometric analysis of the bone response to machined sanblasted titanium implants: an experimental study in rabbit
The aim of this study was to make a comparative analysis between the bone response to machined and sandblasted implants. The sandblasting was done with 150-microns aluminum oxide particles. Under scanning electron microscopic examination, the machined implants presented typical machining grooves, while a very rough, highly irregular surface with depressions and indentations was present on the sandblasted implants. Light microscopy showed a different bone growth pattern on machined (implantopetal growth) and sandblasted (implantofugal growth) implants. No negative effects on the rate of bone growth were observed in spite of the presence of aluminum ions. The histomorphometric analysis showed that sandblasted implants presented, from the third week onwards, a significantly higher contact percentage (P < .0001). These values could point to higher osteoconductivity as a result of the higher surface roughness of sandblasted surfaces
Microbiological and biochemical effectiveness of an antiseptic gel on the bacterial contamination of the inner space of the dental implants: a 3 months human longitudinal study
surgical treatment of periodontal intrabony defects with calcium sulfate implant and barrier versus collagen barrier or open flap debridement alone:a 12 months randomized controlled clinica trial
547 CHOLANGIOCARCINOMA IN ITALY: A NATIONAL SURVEY ON DEMOGRAPHIC AND CLINICAL CHARACTERISTICS, DIAGNOSTIC MODALITIES AND TREATMENT
We report the results of a survey promoted in Italy by the AISF“Cholangiocarcinoma” (CCA) committee aimed to evaluate the demographic and clinical characteristics of IH(intra-hepatic)- and EH(extra-hepatic)-CCA. Members of AISF (Italian Association Liver Disease) and SIGE (Italian Society of Gastroenterology) were asked to fill out a questionnaire describing CCA patients recruited in the last 12 months. 218 consecutive incident CCA cases were analyzed. 47% were EH-CCA and 53% IH-CCA with an age higher for EH-CCA. A history of past smoking, cirrhosis, viral cirrhosis and positivity for viral hepatitis markers were more frequent in IH-CCA than EH-CCA. The clinical onset of the disease was earlier for IH-CCA than EH-CCA. An incidental asymptomatic presentation occurred
in 28% of IH-CCA vs 4% EH-CCA while 74% EH-CCA presented with jaundice vs 28% IH-CCA. Abdominal pain without other symptoms was more frequent in IH-CCA (19.8 vs 4%). Of the 116 IH-CCA cases,
91% presented as single intra-hepatic mass, while 50% EH-CCA was
peri-hilar. Diagnosis was time- and cost-consuming since 70% of all
CCA cases received at least 3 different imaging procedures. Tissue-
proven diagnosis was obtained in 80% of cases. As far as treatment
was concerned, 57% of IH-CCA and 42% of EH-CCA received opensurgery. However, surgery was considered curative in 50/116 IH-
CCA (43%) vs 17/102 (17%) EH-CCA. 18% of IH- vs 4% of EH-CCA
received no treatment. In conclusion, in Italy IH-CCA is managed as
frequently as EH-CCA. In comparison with EH-CCA, IH-CCA occurs
at younger age, is more frequently associated with smoking habits,
cirrhosis and/or hepatitis virus infection and with an incidental
asymptomatic presentation. In contrast, most EH-CCA are jaundiced
at the diagnosis. CCA diagnostic management is cost- and time-
consuming with a curative surgical treatment applicable in 43% IH-vs 17% EH-CCA
Vascular Anomalies Guidelines by the Italian Society for the study of Vascular Anomalies (SISAV)
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