Probability and sensitivity analysis of strain measurements in FRP

Monitoring is an important issue for FRP strengthening systems in order to control their health state. Strain gauges are often used for this aim, but the measures to be utilised can be affected by various factors. In this paper the influence of various factors is taken into account, such as the characteristics of resin coating, the type of glue and the gauge length. The theoretical approach developed in previous work performed on a deterministic basis is extended here to the probabilistic field. The objective is to make a sensitivity analysis of the basic variables which can cause errors in strain measurements. Additionally, the effect of the deviation of the direction of the gauges from the longitudinal direction of the FRP sheets is considered and the existing approach is extended to take this into account. Copyright © 2004 John Wiley & Sons, Ltd

Rassegna storica salernitana. N.s. A.17, n.1(2000)

La Società Salernitana di Storia Patria aderisce al progetto EleA e autorizza la pubblicazione del fascicoloN.s. A.17, n.1(2000): Di Muro, A., Le terre del medio e basso Sele in età longobarda: istituzioni, insediamenti ed economia (secc. VII-XI), P. 7 ; Galdi, A., Il calendario salernitano del 1434, P. 95 ; Tortora, A., Prime note sulla penetrazione dell'evangelismo nel Salernitano, P. 151 ; Basso, P., L'Istituto Casanova di Napoli, P. 173 ; Cerenza F., Francesco Cerenza (1795-1885), P. 231 ; Gallo, I., Antonio Marzullo, P. 245 ; Tesauro Olivieri, P., La donazione tra i fratelli Solimene, nipoti del pittore Francesco, P. 259 ; Petrone, C., Il pensiero di un democratico cristiano sull'azione antifascista, P. 269 ; Recensioni e schede bibliografiche, P. 287-354.Sul recto del frontespizio: fasc. 33 della Nuova Serie (Annata LX dalla fondazione

Characterization of three novel pathogenic SLC40A1 mutations and genotype/phenotype correlations in 7 Italian families with type 4 hereditary hemochromatosis

Mutations of SLC40A1 encoding ferroportin (Fpn), the unique cellular iron exporter, severely affect iron homeostasis causing type 4 hereditary hemochromatosis, an autosomal dominant iron overload condition with variable phenotypic manifestations. This disease can be classified as type 4A, better known as “ferroportin disease”, which is due to “loss of function” mutations that lead to decreased iron export from cells, or as type 4B hemochromatosis, which is caused by “gain of function” mutations, conferring partial or complete resistance to hepcidin-mediated Fpn degradation. In this work, we discuss clinical and molecular findings on a group of patients in whom a SLC40A1 single copy missense variant was identified. Three novel variants, p.D181N, p.G204R and p.R296Q were functionally characterized. Fpn D181N and R296Q mutants can be classified as full or partial loss of function, respectively. Replacement of G204 with arginine appears to cause a more complex defect with impact both on iron export function and hepcidin sensitivity. This finding confirms the difficulty of predicting the effect of a mutation on the molecular properties of Fpn in order to provide an exhaustive explanation to the wide variability of the phenotype in type 4 hereditary hemochromatosi

Characterization of three novel pathogenic SLC40A1 mutations and genotype/phenotype correlations in 7 Italian families with type 4 hereditary hemochromatosis

Mutations of SLC40A1 encoding ferroportin (Fpn), the unique cellular iron exporter, severely affect iron homeostasis causing type 4 hereditary hemochromatosis, an autosomal dominant iron overload condition with variable phenotypic manifestations. This disease can be classified as type 4A, better known as “ferroportin disease”, which is due to “loss of function” mutations that lead to decreased iron export from cells, or as type 4B hemochromatosis, which is caused by “gain of function” mutations, conferring partial or complete resistance to hepcidin-mediated Fpn degradation. In this work, we discuss clinical and molecular findings on a group of patients in whom a SLC40A1 single copy missense variant was identified. Three novel variants, p.D181N, p.G204R and p.R296Q were functionally characterized. Fpn D181N and R296Q mutants can be classified as full or partial loss of function, respectively. Replacement of G204 with arginine appears to cause a more complex defect with impact both on iron export function and hepcidin sensitivity. This finding confirms the difficulty of predicting the effect of a mutation on the molecular properties of Fpn in order to provide an exhaustive explanation to the wide variability of the phenotype in type 4 hereditary hemochromatosi

Morphodynamics of coastal areas represented in the new geomorphologic map of Italy: Draw the landforms of the past to outline the future

In the framework of the revision of Italian geomorphological legend (CARG Project) published in 1994 by the National Geological Service, the AIGeo-Working Group Coastal Morphodynamic (WGCM) dealt with the revision of the legend concerning the landforms of the coast. The aims of the work were the updating of the symbology on the basis of the post-1994 results in the geomorphological researches and creating a legend more vocated to the solution of the problems of applied geomorphology and more suitable to be managed in GIS environment. The WGCM started from the critical analysis of the classifications of coastal landforms proposed during the last century and it continued through a scientific discussion on the work that the members of the group performed by means of 12 case studies in which a correlation between landforms, processes and, dynamics was made. The geomorphological legend proposed by the WGCM has to be considered as a starting point and a work in progress. It remains, indeed, open so that new data can be added and updated as required. Besides, the WGCM tried to contribute to the morphodynamic classification of the coasts around the Mediterranean basin

Geomorphological map of the Italian coast: From a descriptive to a morphodynamic approach.

This study was conducted within the framework of the \u201cCoastal Morphodynamics\u201d Working Group (WG) of the Italian Association of physical Geography and Geomorphology (AIGeo), according to the Institute for the Protection and Environmental Research (ISPRA) for the updating of the legend for the \u201cGeomorphological Map of Italy\u201d. The WG deals with the legend for the coastal areas, focusingits work on marine, lagoon and aeolian landforms, processes and deposits. In particular, the legend aims to classify coastal landforms in order to contribute to hazard and risk assessment,for supportingland-use planning and management. The legend allows the mapping of each landform in function of its genesis as well as its evolution and present dynamics, providing information about morphological characteristics at small and large scales. The relict morphological features and the active ones are reported along with the quantitative parameters useful for the description of the present wave/climate conditions and morphodynamics. As a result of the activities and experiments carried out by the \u201cCoastal Morphodynamics\u201d AIGeo WG during the last years, some examples of coastal geomorphological mappings at different scales (1:5,000 and 1:25,000) have been developed and are presented in this paper. The maps focus both on littoral plains and rocky coast dynamics as well as on the interactions with anthropic modifications

Morphodynamics of coastal areas represented in the new geomorphologic map of Italy: Draw the landforms of the past to outline the future

In the framework of the revision of Italian geomorphological legend (CARG Project) published in 1994 by the National Geological Service, the AIGeo-Working Group Coastal Morphodynamic (WGCM) dealt with the revision of the legend concerning the landforms of the coast. The aims of the work were the updating of the symbology on the basis of the post-1994 results in the geomorphological researches and creating a legend more vocated to the solution of the problems of applied geomorphology and more suitable to be managed in GIS environment. The WGCM started from the critical analysis of the classifications of coastal landforms proposed during the last century and it continued through a scientific discussion on the work that the members of the group performed by means of 12 case studies in which a correlation between landforms, processes and, dynamics was made. The geomorphological legend proposed by the WGCM has to be considered as a starting point and a work in progress. It remains, indeed, open so that new data can be added and updated as required. Besides, the WGCM tried to contribute to the morphodynamic classification of the coasts around the Mediterranean basin

Morphodynamics of coastal areas represented in the new geomorphologic map of Italy: draw the landforms of the past to outline the future

In the framework of the revision of Italian geomorphological legend (CARG Project) published in 1994 by the National Geological Service, the AIGeo-Working Group Coastal Morphodynamic (WGCM) dealt with the revision of the legend concerning the landforms of the coast. The aims of the work were the updating of the symbology on the basis of the post-1994 results in the geomorphological researches and creating a legend more vocated to the solution of the problems of applied geomorphology and more suitable to be managed in GIS environment. The WGCM started from the critical analysis of the classifications of coastal landforms proposed during the last century and it continued through a scientific discussion on the work that the members of the group performed by means of 12 case studies in which a correlation between landforms, processes and, dynamics was made. The geomorphological legend proposed by the WGCM has to be considered as a starting point and a work in progress. It remains, indeed, open so that new data can be added and updated as required