Effects of a School-Based Education Intervention on BMI and Physical Activity

In 2011, the CDC reported that there are 12.5 million obese children and adolescents living in the United States (U.S.). The financial burden of childhood obesity in the U.S. is estimated to be 14 billion dollars. The objective of this evidence-based practice (EBP) project was to answer the question: In school-aged children, how does school-based, structured, family-oriented physical activity education affect body mass index (BMI) compared to usual education over an eight week time period? The Stetler Model of EBP and the health belief model were used to guide this project in a rural, Northwest Indiana elementary school. For eight weeks, fourth and fifth grade students received an additional 30 minutes of classroom education per week about the importance of physical activity and suggestions for increasing daily physical activity using the“Wellness, Academics, and You” (WAY) program as well as other evidence-based materials. Students also participated in brief exercises led by the project facilitator in the classroom each week. Pre- and post-intervention BMIs were measured and compared. BMI data were analyzed using paired t-tests. Although no statistically significant differences in BMI were found (p=0.936), 18.02% (n=20) students lost more than one pound over the eight-week intervention period and 8.12% (n=9) students lost four pounds or more. Future projects with similar objectives to this EBP project may benefit from a longer intervention period

Neuropsychologische Aspekte bei PatientInnen mit Morbus Parkinson

ABSTRACT Theoretischer Hintergrund Morbus Parkinson ist eine progressive, neurogenerative Erkrankung (Vale, 2008). Neben den charakteristischen motorischen Symptomen, spielen auch kognitive/exekutive Beeinträchtigungen eine wichtige Rolle. Sie sind ausschlaggebend für das PatientInnen-Management und für die Lebensqualität der Betroffenen (Schwarz & Storch, 2007). Ziel der Untersuchung Das Ziel der vorliegenden Arbeit ist eine Untersuchung von neuropsychologischen Aspekten der Parkinson-Krankheit. Im Speziellen werden Leistungen bezüglich exekutiver Funktionen im Zusammenhang der Erkrankung ermittelt und auf mögliche Assoziationen mit der affektiven und kognitiven Theory of Mind und dem Entscheidungsverhalten unter Risiko geprüft. Methode Insgesamt wurden 101 Personen mittels neuropsychologischer Tests und Fragebögen begutachtet. Davon waren 47 Personen Morbus Parkinson-PatientInnen und 54 Personen gehörten zur „gesunden“ Kontrollgruppe. Um ein besseres Verständnis über den Verlauf der Erkrankung und der damit einhergehenden kognitiven Beeinträchtigungen zu bekommen, wurden die PatientInnen in einem zweiten Durchgang entsprechend ihres Krankheitsstadiums in 2 Gruppen (frühes Stadium, fortgeschrittenes Stadium) geteilt und ebenfalls mit einer adäquaten Kontrollgruppe verglichen. Ergebnisse und Diskussion Parkinson-PatientInnen, vor allem in fortgeschrittenen Stadien der Erkrankung, schnitten im Vergleich zur Kontrollgruppe in den Aspekten semantisch-kategorielle Wortflüssigkeit, Regel-Erkennung und Regel-Einhaltung, sowie Planungsfähigkeit und Problemlösefähigkeit signifikant schlechter ab. Zudem wurden einige signifikante Assoziationen zwischen den Leistungen in exekutiven Funktionen und den Theory of Mind Kompetenzen als auch dem Entscheidungsverhalten unter Risiko ermittelt. Diese Ergebnisse stimmen großteils mit denen, der publizierten Fachliteratur überein und sollten zur Einleitung gezielten Interventionen für Morbus Parkinson-PatientInnen herangezogen werden

Adverse Drug Reaction Monitoring of Anticancer Drugs in Hematology Department

Background: Cancer is among the leading causes of mortality in India. Studies have reported antineoplastic agents as the common class of drugs causing Adverse Drug Reactions (ADRs). The present study aimed to conduct active surveillance of ADRs of anticancer drugs in the hematology department.Methods: A prospective observational study was conducted in 136 patients with cancer and the incidence and frequency of ADRs were assessed. The study was conducted in 6 months in a multispecialty hospital.Results: Among 136 cancer patients, All was more prevalent (39.70%); CLL, Non- Hodgkin’s Lymphoma were less prevalent (0.73%). ADRs were more prevalent in the Pediatrics department, i.e., 18.53% of ADRs were observed in patients aged <10 years. ADRs in male patients constituted 54.39%, whereas it was 45.60% in female patients. Cytarabine caused the highest number of ADRs (34.48%). The most prevalent ADR was anemia (25.60%).Conclusion: Multiple ADRs were detected in cancer patients. We found that hematological ADRs were more prevalent. Most of the ADRs were possible reactions according to Naranjo and the World Health Organization (WHO) scales

Beilinson-Bernstein Localization

Take a complex reductive group $G$ and its lie algebra $\mathfrak{g}$. Understanding the representations of $\mathfrak{g}$ is a major problem within mathematics. A key tool in this direction is try and realize any such representation as some type of generalized functions on a space. This would allow geometric tools to be applied in order to understand the representations of $\mathfrak{g}$. This is done so in a theorem of Beilinson and Bernstein where they show that any $\mathfrak{g}$ representation can be realized as the global sections of a twisted $D$-module over the flag variety $G/B$, where $B$ is a Borel subgroup of $G$. This paper will provide an exposition of some topics in the geometry of Lie algebras and groups necessary to prove part of this theorem.Mathematic

Efficacy of antioxidant supplementation on conventional and advanced sperm function tests in patients with idiopathic male infertility.

Antioxidants are used in the empirical treatment of infertile men. The aim of this study was to evaluate the effects of antioxidant therapy on conventional semen parameters and advanced sperm function tests in men seeking fertility treatment. A total of 148 infertile men of unknown etiology were divided into idiopathic (n = 119) and unexplained male infertility (UMI; n = 29). All participants were treated with the antioxidant supplement 'FH PRO for Men' for a period of three months. Compared with pretreatment results, there was a significant improvement in conventional semen parameters including sperm concentration, total and progressive motility and normal morphology, and seminal oxidation reduction potential (ORP), and sperm DNA fragmentation (SDF) in idiopathic infertile men. The changes were more prominent in idiopathic infertile men positive for ORP and SDF. UMI patients showed an improvement in progressive motility, ORP, and SDF after antioxidant treatment. Statistical analysis revealed that the efficacy of FH PRO for Men was significant in idiopathic male infertility compared with UMI. Treatment of idiopathic male infertility patients with the FH PRO for Men antioxidant regimen for three months resulted in a significant improvement in conventional semen parameters and sperm function. Therefore, FH PRO for Men offers promise for the medical treatment of idiopathic male infertility