9,523 research outputs found
A Hybrid Quantum Encoding Algorithm of Vector Quantization for Image Compression
Many classical encoding algorithms of Vector Quantization (VQ) of image
compression that can obtain global optimal solution have computational
complexity O(N). A pure quantum VQ encoding algorithm with probability of
success near 100% has been proposed, that performs operations 45sqrt(N) times
approximately. In this paper, a hybrid quantum VQ encoding algorithm between
classical method and quantum algorithm is presented. The number of its
operations is less than sqrt(N) for most images, and it is more efficient than
the pure quantum algorithm.
Key Words: Vector Quantization, Grover's Algorithm, Image Compression,
Quantum AlgorithmComment: Modify on June 21. 10pages, 3 figure
Normal families and fixed points of iterates
Let F be a family of holomorphic functions and let K be a constant less than
4. Suppose that for all f in F the second iterate of f does not have fixed
points for which the modulus of the multiplier is greater than K. We show that
then F is normal. This is deduced from a result about the multipliers of
iterated polynomials.Comment: 5 page
Phonon Density of States and Anharmonicity of UO2
Phonon density of states (PDOS) measurements have been performed on
polycrystalline UO2 at 295 and 1200 K using time-of-flight inelastic neutron
scattering to investigate the impact of anharmonicity on the vibrational
spectra and to benchmark ab initio PDOS simulations performed on this strongly
correlated Mott-insulator. Time-of-flight PDOS measurements include anharmonic
linewidth broadening inherently and the factor of ~ 7 enhancement of the oxygen
spectrum relative to the uranium component by the neutron weighting increases
sensitivity to the oxygen-dominated optical phonon modes. The first-principles
simulations of quasi-harmonic PDOS spectra were neutron-weighted and
anharmonicity was introduced in an approximate way by convolution with
wavevector-weighted averages over our previously measured phonon linewidths for
UO2 that are provided in numerical form. Comparisons between the PDOS
measurements and the simulations show reasonable agreement overall, but they
also reveal important areas of disagreement for both high and low temperatures.
The discrepancies stem largely from an ~ 10 meV compression in the overall
bandwidth (energy range) of the oxygen-dominated optical phonons in the
simulations. A similar linewidth-convoluted comparison performed with the PDOS
spectrum of Dolling et al. obtained by shell-model fitting to their historical
phonon dispersion measurements shows excellent agreement with the
time-of-flight PDOS measurements reported here. In contrast, we show by
comparisons of spectra in linewidth-convoluted form that recent
first-principles simulations for UO2 fail to account for the PDOS spectrum
determined from the measurements of Dolling et al. These results demonstrate
PDOS measurements to be stringent tests for ab initio simulations of phonon
physics in UO2 and they indicate further the need for advances in theory to
address lattice dynamics of UO2.Comment: Text slightly modified, results unchange
Crystallization of the FAD-independent acetolactate synthase of Klebsiella pneumoniae
Leucine and valine are formed in a common pathway from pyruvate in which the first intermediate is 2-acetolactate. In some bacteria, this compound also has a catabolic fate as the starting point for the butanediol fermentation. The enzyme (EC 4.1.3.18) that forms 2-acetolactate is known as either acetohydroxyacid synthase (AHAS) or acetolactate synthase (ALS), with the latter name preferred for the catabolic enzyme. A significant difference between AHAS and ALS is that the former requires FAD for catalytic activity, although the reason for this requirement is not well understood. Both enzymes require the cofactor thiamine diphosphate. Here, the crystallization and preliminary X-ray diffraction analysis of the Klebsiella pneumoniae ALS is reported. Data to 2.6 Angstrom resolution have been collected at 100 K using a rotating-anode generator and an R-AXIS IV++ detector. Crystals have unit-cell parameters a = 137.4, b = 143.9, c = 134.4 Angstrom, alpha = 90, beta = 108.4, gamma = 90degrees and belong to space group C2. Preliminary analysis indicates that there are four monomers located in each asymmetric unit
Crystallization of Arabidopsis thaliana acetohydroxyacid synthase in complex with the sulfonylurea herbicide chlorimuron ethyl
Acetohydroxyacid synthase (AHAS; EC 2.2.1.6) catalyses the formation of 2-acetolactate and 2-aceto-2-hydroxybutyrate as the first step in the biosynthesis of the branched-chain amino acids valine, leucine and isoleucine. The enzyme is inhibited by a wide range of substituted sulfonylureas and imidazolinones and many of these compounds are used as commercial herbicides. Here, the crystallization and preliminary X-ray diffraction analysis of the catalytic subunit of Arabidopsis thaliana AHAS in complex with the sulfonylurea herbicide chlorimuron ethyl are reported. This is the first report of the structure of any plant protein in complex with a commercial herbicide. Crystals diffract to 3.0 Angstrom resolution, have unit-cell parameters a = b = 179.92, c = 185.82 Angstrom and belong to space group P6(4)22. Preliminary analysis indicates that there is one monomer in the asymmetric unit and that these are arranged as pairs of dimers in the crystal. The dimers form a very open hexagonal lattice, with a high solvent content of 81%
Novel water-assisting low firing MoO3 microwave dielectric ceramics
MoO3 ceramics can not be well densified via conventional solid state method and a low relative density (ρ) was obtained (˜64.5% at 680 °C) with a permittivity (εr) ˜ 7.58, a quality factor (Qf) ˜ 35,000 GHz and a temperature coefficient of resonant frequency (TCF) ˜ − 39 ppm/°C. However, cold sintering at 150 °C using 4 wt. % H2O at 150 MPa enhanced densification and give a relative ρ ˜76.8% and εr ˜ 8.31 but with a Qf of only ˜ 900 GHz. The addition of (NH4)6Mo7O24·4H2O further improved densification to give a relative ρ ˜ 83.7% after annealing at 700 °C, resulting in a εr ˜ 9.91 with a Qf ˜ 11,800 GHz. We conclude therefore that oxides that are difficult to be sintered via a conventional solid state route may benefit from cold sintering but despite the higher density, lower Qf cannot be avoided due to the impurities and grain boundary phases that are introduced
Probe substrate and enzyme source-dependent inhibition of UDP-glucuronosyltransferase (UGT) 1A9 by wogonin
Background: Drug-metabolizing enzymes (DMEs) inhibition based drug-drug interaction and herb-drug interaction severely challenge the R&D process of drugs or herbal ingredients.Objective: To evaluate the inhibition potential of wogonin (an important flavonoid isolated from the root of Scutellaria baicalensis) towards one of the most important phase II DMEs, UDP-glucuronosyltransferase (UGT) 1A9.Methods: Both recombinant UGT1A9-catalyzed 4-methylumbelliferone (4-MU) glucuronidation reaction and human liver microsomes (HLMs)-catalyzed propofol glucuronidation reaction were used as two different probe reactions.Results: Wogonin noncompetitively inhibited recombinant UGT1A9-catalyzed 4-MU glucuronidation, and exerted competitive inhibition towards HLMs-catalyzed propofol glucuronidation. The inhibition kinetic parameters (Ki) were calculated to be 3.2 ìM and 52.0ìM, respectively.Conclusion: Necessary monitoring was needed when wogonin was co-administered with the clinical drugs mainly undergoing UGT1A9-mediated glucuronidation elimination. Additionally, probe reactions-dependent inhibition of wogonin towards the activity of UGT1A9 should be paid attention when translating these in vitro data into in vivo situation.Keywords: wogonin, drug-drug interaction (DDI), UDP-glucuronosyltransferases (UGTs
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