Power productivity enhancement using performance analysis of biomass gasifier at energy park, RGTU Bhopal (MP, India)

 Abstract: The concept paper represents possible opportunities for strategic investment in remote area development and further due attention is paid to determine its feasibility.  We examined the status and performance of biomass gasification unit for electricity generation fuelled by woody biomass installed at Energy Centre, Rajiv Gandhi Technological University Bhopal, (India).  The main objective of the research project is to utilize the resources of existing biomass feedstock and make performance analysis under purpose of fulfilling the electrical demand of Energy Centre Rajiv Gandhi Technological University Bhopal (India) and rural users in powering of their home lighting, by means of renewable energy.  The results of the work will be useful for the future engineering development of biomass gasification unit power generation technologies.Keywords: biomass, gasification, co-generation, pyrolysis, combustion, India

Influence of coolant temperature on the performance of a four stroke spark ignition engine employing a dual circuit cooling system

Diesel engines have attracted attention because of their higher thermal efficiency and lower carbon dioxide emissions than gasoline engines.  On the other hand, oxides of nitrogen (NOx) and particulate matter (PM) in the exhaust from diesel engines are difficult to be reduced simultaneously because a decrease in one is likely to result in an increase in the other.  In this paper, an attempt has been made to compare the effect of the heat lost to the coolant in the cylinder block, and in the cylinder head with a conventional cooling circuit with corresponding effects in an engine with a dual cooling circuit.  A dual cooling circuit employs separate cooling circuits for the cylinder block, and for the cylinder head.  A single cylinder, four-stroke, water cooled, naturally aspirated spark ignition engine test rig was developed for the purpose.  The influences of the cylinder block and cylinder head temperatures on brake specific fuel consumption (bsfc) and on exhaust emissions were measured.  The results show that raising the temperature of the coolant in the engine block can produce significant improvements in bsfc with a corresponding reduction in the hydrocarbon (HC) emissions.  Similarly, lowering the coolant temperature in the cylinder head can increase the knock limit of the engine with a corresponding reduction in the levels of NOx in the exhaust emissions.   The objective of this investigation was to access the magnitude of the likely benefits of the dual circuit cooling system.Keywords: dual circuit cooling system, spark ignition engine, heat transfer, engine cooling Citation: Rehman A., R. M. Sarviya, S. Dixit, and R. K. Pandey.  Influence of coolant temperature on the performance of a four stroke spark ignition engine employing a dual circuit cooling system.  Agric Eng Int: CIGR Journal, 2010, 12(1): 84-90.&nbsp

Spectrum of uterine lesions presenting as abnormal uterine bleeding in a rural north Indian population: a study from tertiary care center

Background: Abnormal uterine bleeding (AUB) is now a day’s one of the commonest complains of female patients attending gynaecological OPD and clinics. The problem is not limited to a particular age group and frequently affects reproductive age group as well as peri and postmenopausal females. Endometrial biopsy or curettage is a well-known safe and effective diagnostic procedure in evaluation of abnormal uterine bleeding and ruling out medical causes.Methods: The study was undertaken to ascertain cause of AUB in all patients presenting at gynecology OPD with complain of abnormal uterine bleeding during the period of January 2013 to January 2014.  Relevant clinical data was collected in all cases and endometrial biopsy or hystrectomy specimens were taken for histopathological evaluation.Results: Maximum  number  of  AUB cases (34%) were seen in the age  group of  41-50 years of  age and  predominant  histopathological pattern observed was  proliferative endometrium seen in 18% cases. Leimyoma is another important leading cause followed by bleeding in secretory phase and others. Menorhhagia was the most common clinical presentation. Benign conditions and pregnancy related causes occur mostly in the reproductive age group while premalignant and malignant changes occur in premenopausal and postmenopausal age group.Conclusions: A thorough clinical history, etilogical factors, ultrasound findings along with clinical presentation are important along with histopathological examination which plays a key role in early and prompt diagnosis of  abnormal uterine bleeding.

Hypoglycemic activity of aqueous extract of Urtica parviflora roxb. in normoglycemic rats

In the present study aqueous and ethanolic extract of leaves of Urtica parviflora were evaluated for hypoglycemic effect in normal rats using both 18 hr fasted rat model and oral glucose tolerance test. The aqueous extract of leaves showed a good hypoglycemic response in both the models, while ethanolic extract exhibited very week but insignificant effect, only in 18 hr fasted rat model. The aqueous extract was further tested for effect on intestinal glucose absorption. The amount of glucose absorbed in a segment of jejunum in situ was 13±0.75 mg in presence of aqueous extract vs. vs. 9.05±0.68 mg in control rats during 2 h (P<0.05). Phytochemical screening of aqueous extract revealed the presence of alkaloids, reducing sugars, polysaccharides, tannins, saponins, glycosides and flavonoids. The results indicate that aqueous extract possess significant hypoglycemic activity which may be attributed to, in part by reduction of intestinal glucose absorption by the abovementioned chemical constituents.Keywords: Hypoglycemic activity, Urtica parviflora, Oral glucose tolerance tes

A REVIEW ON CONSTITUENTS, PHARMACOLOGICAL ACTIVITIES AND MEDICINAL USES OF GLYCYRRHIZA GLABRA

Plants have been one of the important sources of medicines for human being and animals since the ancient time. At present scenario there is an increasing demand for herbal medicines, health products and pharmaceuticals products. Herbal medicines have attained popularity at global level to replace the synthetic chemicals as they have shown less adverse reactions. Glycyrrhiza glabra Linn is a commonly used herb for different diseases. Present review article deals with chemical constituents present in various parts of Glycyrrhiza glabra and pharmacological activities. Present article aim to comply all the updated information on its phytochemical and pharmacological activities, which were performed by widely different methods.  Glycyrrhiza glabra Linn possesses antibacterial, antioxidant, antimalarial, antispasmodic, anti-inflammatory and anti-hyper glycemic properties. Various other effects like antiulcer, antiviral, antifungal have also been discussed. This article may be useful for many researchers in discovering potential therapeutic effects and developing new formulations.                       Peer Review History: Received 3 April 2017;   Revised 9 May; Accepted 12 May, Available online 15 May 2017 Academic Editor: Ahmad Najib, Universitas Muslim Indonesia,  Indonesia, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:        Reviewer's Comments: Average Peer review marks at initial stage: 3.5/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. Cecilia Nwadiuto Amadi, University of Port Harcourt Port Harcourt Rivers State, Nigeria, [email protected] Dr. Mohamed Said Fathy Al-Refaey, University of Sadat City, Menofia, Egypt, [email protected] Similar Articles: PHYTOCHEMICAL SCREENING AND IN-VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY POTENTIAL EVALUATIONS OF METHANOLIC EXTRACTS OF COCOS NUCIFERA (L.) LEAVES MURRAYA KOENIGI-A BOON IN DIFFERENT PATHOLOGICAL CONDITIONS Article is cited by: Noor NM, Nazri NZ, Mohamad-Salam NA, et al. The potential of androgenic alopecia management from plant derivatives. Food Research 2020; 4 (Suppl. 2) : 1 – 13 (Pubmed)

KIDNEY STONES FORMATION AND USE OF MEDICINAL PLANTS AS ANTIUROLITHIATIC AGENTS

There is an old and famous fact “the garden is the poor man’s apothecary” and treatment of each and every disease is hidden in nature. Medicinal plants are highly esteemed all over the world as a rich source of therapeutic agents for the prevention and treatment of various diseases. Since ages, herbs are being used for treating different ailments in different parts of world by different communities. A kidney stone, also known as a renal calculus is a solid concretion or crystal aggregation formed in the kidneys from dietary minerals in the urine. The problem of urinary stones or calculi is a very ancient one these stones are found in all parts of the urinary tract, the kidney, and the urinary bladder and may vary considerably in size. Urolithiasis is a complex process that occurs from series of several physicochemical event including super-saturation, nucleation, growth, aggregation and retention within the kidneys. Present article deals with reason, types of kidney stones, risk factors associated, diagnosis and treatment methods including many medicinal plants as herbal option for treatment of urinary stones. Peer Review History: Received 19 August 2017;   Revised 27 August; Accepted 9 September, Available online 15 September 2017 Academic Editor: Ahmad Najib, Universitas Muslim Indonesia,  Indonesia, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:        Reviewer's Comments: Average Peer review marks at initial stage: 5.0/10 Average Peer review marks at publication stage: 7.5/10 Reviewer(s) detail: Dr. R. Karthikeyan, Vignan pharmacy college, Guntur, A.P., India, [email protected] Dr. Alfonso Alexander Aguileral, University of Veracruz,  Mexico, [email protected]

TABLET GRANULATION: CURRENT SCENARIO AND RECENT ADVANCES

Granulation is a size enlargement process, in fine or coarse particles converted into physically stronger and larger agglomerates having good flow property, better compression characteristics and uniformity, prevent segregation of the blend components, improve content uniformity, and eliminate excessive amounts of fine particles. Size of granules has a size range of 0.2 to 4.0 mm, depending on their subsequent use. Size of the granules depends on the quantity and feeding rate of granulating liquid. The selection of process to prepare granules requires thorough knowledge of physicochemical properties of the drug, excipients, required flow and release properties, to name a few. At current scenario available technologies includes, spray drying, roller compaction, high shear mixing, and fluid bed granulation etc. The objective of present work is to focus on the commonly used and novel granulation technologies like such as pneumatic dry granulation, steam granulation, moisture-activated dry granulation, thermal adhesion granulation, freeze granulation, and foamed binder or foam granulation. Peer Review History: Received 13 September 2017;   Revised 25 October; Accepted 30 October, Available online 15 November 2017 Academic Editor: Dr. Sally A. El-Zahaby, Pharos University in Alexandria, Egypt, [email protected] Received file:        Reviewer's Comments: Average Peer review marks at initial stage: 3.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Dr. Francis Adou Yapo, Felix Houphouet Boigny, University of Abidjan, Ivory Coast, [email protected] Dr. Hebatalla Ibrahim Ahmed Abdel Hameed, Al-Azhar University, Faculty of Pharmacy (Girls), Nasr City, Cairo, Egypt, [email protected] Similar Articles: IN VITRO-IN VIVO BIO-EQUIVALENCE CORRELATION STUDY OF ATENOLOL, AND ITS BRANDS OF IMMEDIATE RELEASE TABLET UNDER BIO-WAIVER CONDITION

Estimation and comparison of thrombocyte count by peripheral blood smear method and automated method in women with pregnancy

Background: Thrombocyte is important and very essential component of blood and have significant role in maintenance of hemostasis. Thrombocyte count is an important investigation done in various acquired and congenital coagulable states which include conditions like pregnancy. Thrombocyte count is routinely done by automated hematology analyzer method. The automated hematology analyzer counters are not usually available at all centres especially in peripheral and rural side though thrombocytes can also be assessed from the peripheral blood smears, which can be easily and precisely done at any set up. Aim and objective of this study was to compare the thrombocyte estimation by peripheral blood smear method and automated hematology analyzer in pregnant women.Methods: Thrombocyte estimation was done from samples taken from 120 normal pregnant women between December 2018 to March 2019, where samples were Ethylene Diamine Tetra Acetic acid (EDTA) anticoagulated. Thrombocyte was counted manually using PBS (Leishman stain) and hematology analyzer (Sysmex XN1000 series). Thrombocyte counts were expressed in Mean and standard Deviation. Statistical analysis was done by student’s t test using MS excel and SPSS version 17.Results: Thrombocyte count by PBS have mean value of 2.04 lacs/mm3 with standard deviation of 0.56 lacs/mm3 and by automated method have mean value of 1.89 lacs/mm3 and standard deviation of 0.71 lacs/mm3 with p value 0.010. Thus, there was no statistically significant difference found between two methods.Conclusions: Estimation of thrombocyte count on the basis of manual thrombocyte count is a reliable technique and can be used to validate automated thrombocyte counts. It can also be used in under resourced laboratories, where there are no automated counters of good precision available. In fact, all the tests showing abnormal thrombocyte counts must be reported only after cross examining on PBS

SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL IMIDAZOLE BASED COMPOUNDS

Objective: Some new imidazole derivatives (3i-xii) were synthesized as per design synthetic protocol scheme. The structures of newly prepared compounds were confirmed by modern analytical technique and elemental analysis. Methods: All the synthetic compounds were screened for their antimicrobial activity against bacterial results showed good to remarkable activity. The MIC (minimum inhibitory concentration) values were determined by comparison to ciprofloxacin (anti-bacterial) and fluconazole (anti-fungal) as standard drug. Among them, compound 3iv and 3x exhibited notable antimicrobial activity. These compounds may be used as new template for the searching of potential antimicrobial agents. Results: The purity of the compound was verified with the help of TLC (B: A, 9:1). % age of yield was found 83% and melting point noted 151-1520C. Compounds (3ii, 3viii and 3ix) were shown moderate activity against E. coli, S. aureus, M. luteus and K. pneumonia, whereas compounds (3iii, 3vii, 3xi and 3xii) showed mild activity against few bacterial strainsμg/ml.  The compounds of electron releasing imidazole derivatives (3ii, 3iv, 3viii, 3ix, 3x and xi) presented comparatively better anti-fungal activity than the compounds of electron withdrawing imidazole derivatives (3iii, 3vii and 3xii). Conclusion: The biological activity result revealed that all the newly synthetic compounds 3i-xii [4-(biphenyl-4-yl)-2-(substituted phenyl)-1H-imidazole] exhibited better antibacterial activity as compared to antifungal activity in compare to reference drug.        Peer Review History: Received 7 February 2017;   Revised 11 March; Accepted 13 March, Available online 15 March 2017 Academic Editor: Dr. Asia Selman Abdullah, Al-Razi university, Department of Pharmacy, Yemen, [email protected] UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file:        Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 8.5/10 Reviewer(s) detail: Dr. Emmanuel O. Olorunsola, Department of Pharmaceutics & Pharmaceutical Technology, University of Uyo, Nigeria, [email protected] Dr. Xinwei Li, Jilin University, China, [email protected] This article has been cited by: Recent developments in orally disintegrating mini tablets Sachin Sarashetti, Vikas Jain, Gowda D V, Pooja Mallya, Satish Babu. International journal of research in pharmaceutical sciences 2020, 11(3), 3606-3612. Pubme

Synthesis of new Imidazole Derivatives as effective Antimicrobial Agents

In the present work, some new imidazole derivatives (3i-xii) were synthesized as per design synthetic protocol scheme. The structures of newly prepared compounds were confirmed by modern analytical technique (IR, 1H-NMR, Mass spectral data) and elemental analysis, results found in full agreement with their assigned structures. All the synthetic compounds were screened for their antimicrobial activity against bacterial strains viz. Escherichia coli (E. coli, MTCC 2961), Staphylococcus aureus (S. aureus, MTCC 3160), Bacillus subtilis (B. subtilis, MTCC 121), Klebsiella pneumoniae (K. pneumoniae, MTCC 3040) and Micrococcus luteus (M. luteus, MTCC 7527)) and fungal strains viz. Candida albicans (C. albicans, MTCC 227), Aspergillus niger (A. niger, MTCC 277) and Aspergillus flavus (A. flavus, MTCC 418) ; results showed good to remarkable activity. The MIC (minimum inhibitory concentration) values were determined by comparison to ciprofloxacin (anti-bacterial) and fluconazole (anti-fungal) as standard drug. Among them, compound 3iv and 3x exhibited notable antimicrobial activity. These compounds may be used as new template for the searching of potential antimicrobial agents