Ayurvedic management of a patient with Hypoxia and Co-Morbidities by Home Care through Telehealth in 2nd wave of COVID-19 - Case Report

Ayurvedic herbal combinations like Kasaya, Churna and Vati are very useful even in the moderate to severe patients with oxygen support. It was reported that Ayurveda medication can prevent further progression of inflammatory phase (cytokine storm) and prothrombic phase (Organ failure) of Covid- 19 infection. Rasa Rasayana are thought to be more potent and quicker in action as compared to Ayurvedic herbal combination in Jvara Chikitsa (Fever) and are potent Immuno boosters also. A 42 years male consulted an Ayurvedic Physician with breathing difficulties and redness of eyes and face. His SPO2 was 85%and HRCT of thorax’s severity score was 14/25 with Diabetes and Hypertension as pre-existing co-morbidities. The patient had received Ayush-64, Siddha Makardwaja, Swasa Kasa Chintamani Rasa for the first three days of treatment along with oxygen therapy after that Dasamoola Haritaki was added. The patient showed clinical improvement within a day of administration of Ayurvedic medicines and felt good. His cough and breathing difficulties have substantially reduced and his SPO2 became stable between 94 and 96% in two days. This case report highlights the clinical success story as a result of administration of Ayurvedic Rasa-Rasayana and herbal combination in early Inflammatory phase of COVID-19 infection without the use of synthetic steroid and reducing the oxygen requirement needed for home care set up through telehealth service. It may sensitize the reader for early detection and management of similar or identical cases

Pre Renal Assessment For A Successful Kidney Transplant

Introduction:Living donor kidney transplantation is the treatment of choice for patients with end stage kidney disease, which prevents chronic dialysis and its long term side effects. In addition to the detailed clinical history and thorough laboratory testing, anatomical assessment of kidneys, pre donation kidney volume and its function before transplantation are important factors to assess post transplant outcome. Materials and methods: Patients undergoing first renal transplant and those between age group of 18 to 60 years were included in the study. Donor kidney volume was measured ultrasonographically, from which donated kidney volume was calculated to evaluate GFR of the donated kidney from the total GFR of the donor. Estimation of recipient graft function was done using four variable abbreviated MDRD equation at 3, 6, 9 and 12 months post transplant. Results :Correlation of the donor age and donor kidney volume with recipients eGFR was done and the results were tabulated. Statistical analysis was done and correlations were seen with Pearson’s correlation coefficient. Statistical significance was defined as p value 0.05. Conclusion: Living donor kidney transplantation remains one of the vitally important treatment option for the end stage renal disease patients. Estimation of donor kidney volume, eGFR and donor age all together play an important role in post transplant graft survival and also better renal outcomes and functioning

POTALA KATUROHINYADI KWATHA IN KAPHAJA YAKRIT DALLUDARA (NON-ALCOHOLIC FATTY LIVER DISEASE): A CASE STUDY

Non- alcoholic fatty liver disease (NAFLD) is also otherwise termed as Hepatic steatosis and Kaphaja yakrit dalludara in Ayurveda. 34 years male patient, highly educated from a high socio-economic group of Non vegetarian diet habit came to hospital with complain of anorexia, indigestion and distention for three months. The clinical findings revealed that he is slightly obese, hyperglycaemia and dyslipidimia along elevated liver enzymes with fatty liver in USG and Fibro scan. The case was treated with Patolakaturohinyadi Kwatham (PKK) in the dose was 30ml Kasaya with equal quantity of luke warm water twice daily in empty stomach preferable morning and evening for six months. This study proved that PKK can significantly reduced blood sugar, serum Lipids and liver enzymes within three months along with reduction weight and BMI, but change in liver architecture required six months in this therapy. The BARD score and NAFLD score changed to normal after six months of therapy. The patient was kept in observation for further one year without medication and advised to practice yoga, exercise and low carbohydrate and fat diet to study the recurrence of disease. The liver architecture as well as biochemical profile of liver is maintained after one year also. PKK may correct the metabolic dysfunction by increase Agni, digest Ama which helped in the correction of hyperglycaemia and dyslipidaemia. PKK is safe in for six months of use in recommended dose (30ml BID) as there was no adverse sign and symptom observed and no change in biochemical and Haematological profile of Patients.PKK is safe and effective in this case of Kaphaja Yakrit dalludara (NAFLD). It can study further in large population to generated evidence for its efficacy and efficacy in larger group

Role of Krimi (Pathogen) in Aupasarkika Yakrit Vikara (Infective Liver diseases) - A Narrative Review

Infective liver diseases are more than 18% of total Chronic Liver Diseases and been ranked as the fifth most common cause of death worldwide. Krimi can create systemic infection like - Jvara, Vibarnata (skin rash), Shula (Pain), Bhaktadwesa (anorexia), Krimija Pandu (Anaemia) etc. to organ specific disorders like - Krimi Danta, Krimi Karna, Asadhya Pratisyaya, Krimi Granthi, Krimija Hrudroga, Krimija Shira Roga But Krimijayakrit Vikara/Roga is not found in classical literature. A considerable number of Infectious liver disease patients came to various Ayurveda Hospital and expert Ayurveda physicians either feed up with conventional treatment or cannot bear the expenses of conventional therapy. Therefore, it is an attempt to establish the role of Krimi in Aupasarkika Yakrit Vikara through reviewing Ayurveda and modern literature with some experience-based inputs. Virus, bacteria, protozoa can be Adrisya Krimi (not visible in necked eye), Anu (minute) and Suksma and Nematodes and fungus are Drisya (Visible) Krimis. Purisaja and Raktaja Krimi can produce Krimija Yakrit Roga as near to Liver and through gut - liver axis and rich circulation of liver. Jvara (Fever), Shula (abdominal pain), Mandagni (low digestive power), Pita Netrata (Jaundice) are cardinal symptom of Krimija Yakrit Roga. In three dosas, Kapha Dosa is more aggravated in Krimija Yakrit Roga. Rakta Vaha Srotas and Purisha Vaha are mostly affected Srotas in Krimija Yakrit Roga. Sahaja Krimi or Avaikarik Krimi are said to be gut microbiota which are more than 100 trillion microorganisms in the gut show high metabolic activity and are continuously helping with the host immune system through gut-liver axis. Krimija Yakrit Roga can be a type of Yakrit Roga which clinically manifested as Yakritdalludara (Hepato megaly) and Yakrit Kshyaya (Cirrhosis of Liver). Successful diagnosis of type of Krimi can be possible though careful history and appropriate microbial and radiological studies for proper treatment of liver diseases

Uncertainties and Dynamic Connectedness Among Sectors: A Case of the USA, India, France, Germany and Russia

This study examines the connectedness among the sectoral indices for the USA, India, France, Germany and Russia stock markets pre and post-COVID-19. We use the Diebold and Yilmaz spillover index to examine the study\u27s objectives. This study finds that volatility spillover is higher during COVID-19 than before COVID-19. In addition, the volatility transmission across the sectors demonstrated mixed results regarding net volatility receivers and transmitters. However, the degree of transmission is higher for the net volatility receivers than for the net volatility transmitters. This study will help policymakers draft related policies to immunise their economy and market from spillover contagions of international markets during varying pandemic scenarios. This study would also help potential investors, including foreign institutional investors, diversify their portfolios based on the sectors with net volatility transmitters and receivers

Rourkela steel plant automation:A case study

n order to improve product quality, reduce cost, increase customer satisfaction and to sustain the global competition, automation in the existing infrastructure of the steel industry is essential. After liberalization started in the steel sector in India, a large number of steel plants have come up with most advanced technology. In this paper automation process in Integrated material management system (IMMS), Electronic Procurement system (EPS), Product Planning and Control System (PPCS) are discussed and possibility of implementation of ERP and GPS based transportation system is discussed for automation

A Comprehensive Review on AISI 4340 Hardened Steel: Emphasis on Industry Implemented Machining Settings, Implications, and Statistical Analysis

Turning of hardened AISI 4340 steel is regarded as one of the demanding challenges in machining sectors where precision tolerances are essential for automobile parts. The AISI 4340 steel is broadly utilized in forged steel automotive crankshafts systems, hydraulic forged and additional machine tool purposes because of their improved characteristics.  Moreover, one of the keys confronts in the machining of hard 4340 steel is the comparatively deprived machining behavior that reduces the functionality of the material and further leads to component  rejection at the final inspection stage. In addition, accelerated tool wear necessitates for repeated changing of cutting tool that results in higher machining and tooling costs. This comprehensive review aimed to present in-depth features on the development of machining performances using various cutting tools. This review focus is to provide a broad perceptive of the role of controllable variables during machining of hardened steel. This review analysis examines the response variables and its advantages on chip morphology and heat generation. The comprehensive overview of machining settings, key machinability indicators and statistical analysis for AISI 4340 steel has been presented. This overview will provide academic, industrial and scientific communities with benefits and shortcomings through improved conceptual understanding towards further research and development

Pathya & Apathya (Wholesome & Unwholesome diet and regimen) in Yakrit Kshaya (Liver Cirrhosis) : A Narrative Review

Yakrit Kshaya (Liver Cirrhosis) is associated with vitiated Agni (digestive power), production of Ama (Undigested food) and Anuloma and Pratilomakshyaya (forward and backward depletion of Dhatu). Approximate 20% compensated cirrhosis patients and 65-95% decompensated cirrhosis patient have either Anuloma Dhatu Kshaya (forward depletion) or Pratilomana Dhatu Kshaya (backward depletion) or both types of malnutrition. Pathya (wholesome diet and regimen) is defined as the Ahara (Diet) and Vihara (regimen) that give proper nutrition to body and mind, clear the micro channels of Body (Pantha/Marga/Srotas), and provide happiness; that opposite is Apathya(unwholesome diet and regimen). A Pathya and Apathya chart for Yakrit Kshaya (Liver Cirrhosis) is prepared and presented. Chinta (anxiety), Shoka (depression), Krotha (anger), Duhkha (sorrow), Dukkha Shaiya (uncomforted bed) and Ratrijagarana (insomnia) can contribute for the indigestion even if a small quantity of Pathyaahara (wholesome diet). Normal diet with Goghruta (ghee) prepared from curd (Emulsified fat), Mamsa Rasa, milk can balance the protein. The Yakrit Kshaya patients should eat 6-8 times in small quantity (snax, mini meal ) as their Agni is low to very low. Mid night meal is also advisable for reduce protein breakdown. Restriction of water, sour and salty foods, fast foods are very crucial for the treatment outcome as it create Ama. More research on Pathya (Ayurveda diet) in Yakritkshaya (Liver cirrhosis) is encouraged

Ayurvedic treatment outcome for Chronic Liver diseases

Currently available medical therapies for liver disorders have more systemic toxicity, cost effective and liver transplantation was advised to many cases. So many patients want to take ayurveda medication as last choice or as a choice due to poverty. We have documented more than 200 cases and found 40% cases are Non Alcoholic Fatty liver diseases followed by Cirrhosis of liver. There are more than three hundred herbo-mineral preparations in Ayurveda system of medicine for the treatment of jaundice and chronic liver diseases. More than 50% people of our country relay on Ayurveda and herbal medicine for liver diseases. Ayurveda medicine could represent a promising tool to postpone the need of liver transplantations, increase the QoL of patients with cirrhosis, and reduce overall treatment costs of Chronic liver diseases. Ayurveda also delivered sodhana ( Purificatory treatment) by means of Panchakarma treatment. Rasayana therapy is very helpful in CLD. Diet has a integral role in Outcome of a CLD patient. Evidences are coming for remission of hepatao-cellular carcinoma and reversal of fibrosis of liver with high life expectancy. So public participation as well as awareness for Ayurveda treatment in Chronic liver diseases are required. Proper training and modern skill development should be mandatory for of Ayurveda Physicians treating liver diseases . More evidences in terms of Ayurveda outcome studies are the need of the hour to create a hope for CLD Patients

Structural, Dielectric and Electrical Characteristic of Bi0.5Pb0.5[Fe0.1La0.4(Zr0.25Ti0.25)]O3

The polycrystalline compound Bi0.5Pb0.5 [Fe0.1La0.4 (Zr0.25Ti0.25)]O3 was synthesized by substituting Pb, La, Zr and Ti ions on perovskite structured bismuth ferrite (BFO) with the help of mixed oxide solid state reaction method. The present work is to observe the effect of off-valence and iso-valence substitution on the dielectric and electric properties of bismuth ferrite (BFO). The room temperature XRD pattern of the calcinated powders of the sample reveals that the crystal structure is tetragonal with space group P4mm, while BFO has rhombohedral structure with space group R3c. The SEM of the sintered pellet of the compound indicates that the small grains are uniformly distributed over the surface. Complex impedance spectroscopy (CIS) was adopted to analyze the dielectric, impedance and conductivity behavior of the compound. The results show that the dielectric loss in the material is significantly less than that of BFO and the dielectric and ferroelectric behavior of the sample get enhanced. The complex impedance plots show the existence of non-Debye type of relaxation phenomena, which is caused by resistive and capacitive effect of the bulk and grain boundaries. The Arrhenius plot for the compound indicates that the material possesses NTCR behavior. The frequency response of ac conductivity obeys Jonschers law and UDR (universal dielectric response).[Key words: off-valence, iso-valence, CIS, non-Debye type relaxation, NTCR, UDR