A Study of the Conformers of the (Nonafluorobutanesulfonyl)imide Ion by Means of Infrared Spectroscopy and Density Functional Theory (DFT) Calculations

Pyrrolidinium-based ionic liquids with anions of the per(fluoroalkylsulfonyl)imide family are particularly interesting for their use as electrolytes in lithium batteries. These ions have several geometric isomers and the presence of different ion conformers and their distribution affects the ILs (Ionic liquids) physical and chemical properties. In the present work, we report the temperature dependence of the infrared spectra of the N-butyl-N-methyl-pyrrolidinium(trifluoromethanesulfonyl) (nonafluorobutanesulfonyl)imide (PYR14-IM14) ionic liquid; DFT (Density Functional Theory) calculations performed with different models provides indications about the IM14 conformers and their vibrational spectra. Moreover the temperature dependence of the intensity of the lines identified as markers of different conformers provide indications about the conformers’ distribution and the difference of their enthalpy in the liquid phase

Virtual and rapid prototyping of an underactuated space end effector

A fast and reliable verification of an initial concept is an important need in the field of mechatronics. Usually, the steps for a successful design require multiple iterations involving a sequence of design phases-the initial one and several improvements-and the tests of the resulting prototypes, in a trial and error scheme. Now a day’s software and hardware tools allow for a faster approach, in which the iterations between design and prototyping are by far reduced, even to just one in favorable situation. This work presents the design, manufacturing and testing of a robotic end effector for space applications, realized through virtual prototyping, followed by rapid prototyping realization. The first process allows realizing a mathematical model of the robotic system that, once all the simulations confirm the effectiveness of the design, can be directly used for the rapid prototyping by means of 3D printing. The workflow and the results of the process are described in detail in this paper, showing the qualitative and quantitative evaluation of the performance of both the virtual end effector and the actual physical robotic hand

Hélène Carles, Trésor galloroman des origines (TGO). Les trajectoires étymologiques et géolinguistiques du lexique galloroman en contexte latin (ca 800-1120)

Dans cet ouvrage imposant, introduit par une élégante Prefazione par Pietro Beltrami (p. XIII-XV), Hélène Carles propose une étude très fine et approfondie des lexèmes vernaculaires qu’elle a dégagés grâce au dépouillement des quelque 5 000 chartes en latin composant la collection Chartes originales antérieures à 1121 conservées en France, éditée et mise en ligne en 2008 par l’Atelier de recherche sur les textes médiévaux (Artem). Le butin ainsi amassé s’élève, après l’indispensable tri, à 51..

«Des livres verrez cent, A vostre choiz, du grant jusqu’au mineur». À propos de la bibliothèque de Pierre et Jean Sala

L’objectif de cette contribution est à la fois ambitieux – peut-être même trop ambitieux – et modeste. En effet, mon propos est d’observer un phénomène de vaste portée, en le regardant, pour ainsi dire, par le «trou de la serrure». Le phénomène de vaste portée, c’est la formation de la culture lyonnaise entre la fin du xve siècle et le début du xvie siècle. Le «trou de la serrure», c’est celui qui donne sur la bibliothèque de la famille Sala, et plus précisément sur les bibliothèques des deux..

THE PATIENT IN THE OPERATING ROOM: CONSIDERATION AT SEVEN YEARS FROM WORLD HEALTH ORGANIZATION GUIDELINES PUBLICATION.

Modern surgery is burdened by a huge amount of patient to be treated and an increasingly complex number of procedures which request planned action and shared behaviours, aimed to prevent perioperative accidents and favour good surgical outcomes. Surgical and anaesthetic safety has improved significantly in last few decades. However, the operating room environment continues to have significant safety risks for patients as well as the health care providers who work there. Adverse events may result from problems in practice, products, procedures or systems. The worldwide incidence of surgical site infection, one of the most important and frequent post-operative complication, ranges from 3% to 16%, with a mortality rate ranging from 0.4% to 0.8%; in these studies, about 50% of cases were considered preventable (1-9). Patients safety improvements demand a complex system-wide effort, involving a wide range of actions in performance improvement, environmental safety and risk management, including infection control, safe use of medicines, equipment safety, safe clinical practice and safe environment of care. Just as public health interventions and educational projects have dramatically improved maternal and neonatal survival, analogous efforts might improve surgical safety and quality of care (10). According to these objectives, the World Health Organization (WHO) has published and diffused the international “Guidelines for Safe Surgery” (11). The guidelines have the clear proposal to 61ameliorate the safety of surgical interventions; they define and promote recommendation and safety standards suitable for the different Countries and operative settings, suggesting a new deal in managing pre-operative, intra-operative and post-operative processes. On the base of these recommendations, the WHO has also developed a checklist for the safety in the operating room, in order to prevent avoidable adverse events, thus minimizing unnecessary loss of life and serious complications. The results raised from a multicentre study carried out in eight different Countries, demonstrating the effectiveness of the WHO checklist in terms of better patient safety, reduction of deaths and post-operative complications (12). The objectives of this international effort are resumable as follow: 1. the patient must be correctly positioned on the surgical bed and prepared; 2. the surgery team must operate on the correct patient at the correct site; 3. blood loss and risk for surgical site infection must be minimized; 4. inadvertent retention of instruments and sponges in surgical site must be prevented; 5. during surgery, anaesthesiologists must prevent harm from the administration of anaesthetics, while protecting the patient from pain; 6. anaesthesiologists must manage patient’s airways and respiratory function, in order to avoid life-threatening complications; 7. the team should consider patient’s allergies or intolerances in order to prevent an allergic or adverse drug reaction; 8. at the end of intervention, the surgical team must secure and accurately identify all surgical specimens, while the anaesthesiologists will guarantee a correct patient awakening; 9. all the members of the team will effectively communicate and exchange critical information for the safe conduct of the operation; 10. post-operative thromboembolism must be prevented adopting the right measures; 11. each member of the team is responsible for his own clinical documentation; 12. hospitals and public health systems will establish routine surveillance of surgical capacity, volume and results. On March 2013, the American Agency for Health Research and Quality (AHRQ) published the Making Health Care Safer II report, which confirmed the effectiveness of WHO checklist and considered it as one of the 10 strongest recommended practices health care organizations should immediately apply to improve patient safety (13). After the first launch of the WHO checklist, the American Veteran Health Administration observed a constant reduction of patient mortality (0.5/1000 surgeries/4 months); in Holland, compliance to the new guidelines raised from 12% of the first 4 months to the 60%, observed at the end of the second year after publication. This means that «The checklist only works if you use it» (14). The checklist does not reduces itself patient complications, but only the application of all the provided items could help to do so. The checklist should be understood not merely as a list of items to be checked off, but as an instrument for the improvement of communication, teamwork, and safety culture in the operating room, and it should be accordingly implemented. To reach the expected results it needs time, the time to let surgical team to learn and involve (gradually) all the interested units of a determined hospital or the hospitals of a specific geographic area. Agreeing with Bosk and colleagues (15), using an electronic recording format within the standard mandatory strategy facilitates apparent compliance and the use of the safety checklist as a tick box exercise. It seems that the main trick to improving safety is a strategy leading to positive attitudes on the part of the health professionals involved, involving a far more complex adaptive process than merely mandating the use of a checklist