3 research outputs found
Aivokasvainten hoito ja moniammatillinen neuro-onkologiaryhmä
Kallonsisäisissä kasvaimissa haasteet kuvantamisessa, molekyylipatologiassa ja hoidonvasteen arvioinnissa ovat suurempia kuin monissa yleisemmissä syövissä. Hiljattainpäivitetty molekyylimuutoksiin perustuva WHO:n keskushermoston kasvainten luokitteluon oleellinen sekä hoidon valinnassa että haittavaikutusten riskin arviossa. Neuro-onkologiaryhmässäneurokirurgi, syöpälääkäri, neurologi, neuroradiologi ja -patologi täydentävät toistensaerityisosaamista. Monialainen hoidon suunnittelu parantaa ja yhdenmukaistaa laatuaja mahdollisesti ennustetta, vaikka näyttö aikuisten glioomassa on vasta alustavaa.Ryhmän ohjeistama seuranta helpottaa ymmärtämään hoitojen vaikutusta potilaan toimintakyvynsäilyttämiseen. Samalla ryhmä saa palautetta hoidon tehosta ja viiveet vähenevät,kun koordinoidaan diagnostiikka ja hoidon toteutus kansainvälisiä ja kansallisia suosituksianoudattaen. Palaute on keskeistä neuro-onkologisen hoidon vaikuttavuuden ja laadunkehittämiselle.</p
Controlled register-based study of road traffic accidents in 12,651 Finnish cancer patients during 2013-2019
Background: Little controlled evidence exists on road traffic accident (RTA) risk among patients diagnosed with cancer, while clinicians are often requested to comment their ability to drive. The aim of this study was to evaluate RTA risk in a population-based cohort of cancer patients living in Southwest Finland.Patients: All adult patients diagnosed with cancer in 2013-2019 were included. Acute appendectomy/cholecystectomy and actinic keratosis patients without cancer were selected from the same region as the control cohort. Participants were cross-referenced to a national driving licence database, yielding 12,651 cancer and 6334 control patients with a valid licence. Due to marked differences in their clinical presentation, the cancer cohort was divided into nine cancers of interest (breast, prostate, colorectal, lung, melanoma, head & neck, primary brain tumours, gynaecological and haematological malignancies). The nationwide law-regulated motor liability insurance registry was searched for all RTAs leading to injury with claims paid to not- or at-fault participants. At-fault drivers were verified based on sex and birth year.Results: During a median follow-up of 34 months, 167 persons were at-fault drivers in RTAs leading to injury. Among the nine cancers of interest, RTA risk did not differ from the control cohort. Among cancer patients, multivariable regression suggested male sex and opioid use, but not advanced cancer stage or given systemic therapy, as the most influential risk factors for RTA.Conclusions: Cancer diagnosis itself was not associated with increased RTA risk, but other associated symptoms, medications, comorbidities or specific cancer subgroups may.</p